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How We Think about Targeting RNA with Small Molecules

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.8880-8900

2020

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SP-0321: The British Institute of Radiology

Radiotherapy and oncology, 2016-04, Vol.119, p.S147-S148

Hafeez, S

2016

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The energy dissipation of a test-charge particle within a dense, degenerate electron- positron-ion plasma

Physica scripta, 2024-06, Vol.99 (6), p.65606

2024

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Targeted Degradation of the Oncogenic MicroRNA 17-92 Cluster by Structure-Targeting Ligands

Journal of the American Chemical Society, 2020-04, Vol.142 (15), p.6970-6982

2020

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Assessment of safety and quality aspects of boiling treatment of quail eggs

Letters in applied microbiology, 2022-08, Vol.75 (2), p.410-421

2022

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Adaptive Radiotherapy Enabled by MRI Guidance

Clinical oncology (Royal College of Radiologists (Great Britain)), 2018-11, Vol.30 (11), p.711-719

2018

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Image-guided Adaptive Radiotherapy for Bladder Cancer

Clinical oncology (Royal College of Radiologists (Great Britain)), 2021-06, Vol.33 (6), p.350-368

2021

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Targeting the SARS-CoV‑2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders

ACS central science, 2020-10, Vol.6 (10), p.1713-1721

2020

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Programming inactive RNA-binding small molecules into bioactive degraders

Nature (London), 2023-06, Vol.618 (7963), p.169-179

2023

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Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAs

Cell chemical biology, 2018-09, Vol.25 (9), p.1086-1094.e7

2018

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A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype

Cell chemical biology, 2022-02, Vol.29 (2), p.300-311.e10

2022

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Markers of optimal medical therapy are associated with improved limb outcomes after elective revascularization for intermittent claudication

Journal of vascular surgery, 2024-08

2024

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Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions

Nature chemistry, 2020-10, Vol.12 (10), p.952-961

2020

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Selective Small Molecule Recognition of RNA Base Pairs

ACS combinatorial science, 2018-08, Vol.20 (8), p.482-491

2018

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Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera

Proceedings of the National Academy of Sciences - PNAS, 2024-01, Vol.121 (2), p.e2306682120

2024

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A map of the SARS-CoV-2 RNA structurome

NAR genomics and bioinformatics, 2021-06, Vol.3 (2)

2021

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Diagnosis of Transthyretin Amyloid Cardiomyopathy

Cardiology and therapy, 2020-06, Vol.9 (1), p.85-95

2020

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Hydrogels that listen to cells: a review of cell-responsive strategies in biomaterial design for tissue regeneration

Materials horizons, 2017-01, Vol.4 (6), p.12-14

2017

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Correlation of Clinician- and Patient-Reported Outcomes in the BC2001 Trial

Clinical oncology (Royal College of Radiologists (Great Britain)), 2023-05, Vol.35 (5), p.331-338

2023

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Differences in Quality of Life and Toxicity for Male and Female Patients following Chemo(radiotherapy) for Bladder Cancer

Clinical oncology (Royal College of Radiologists (Great Britain)), 2023-05, Vol.35 (5), p.e336-e343

2023

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Failing to Close the Gap Between Evidence and Clinical Practice in Radical Bladder Cancer Radiotherapy

Clinical oncology (Royal College of Radiologists (Great Britain)), 2021-01, Vol.33 (1), p.46-49

2021

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Antibiotic resistance pattern and pathological features of avian pathogenic Escherichia coli O78:K80 in chickens

Brazilian journal of biology, 2024, Vol.84, p.e257179-10

2024

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Unravelling the Phytochemical Composition and Antioxidant Potential of Different Parts of Rumex vesicarius L.: A RP-HPLC-MS-MS/MS, Chemometrics, and Molecular Docking-Based Comparative Study

Plants (Basel), 2024-07, Vol.13 (13), p.1815

2024

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Use of diffusion weighted-MRI (DW-MRI) as a prognostic biomarker of survival and time to cystectomy in muscle invasive bladder cancer (MIBC) following organ conserving treatment

European journal of cancer (1990), 2017-02, Vol.72, p.S192-S192

2017

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Systematically Studying the Effect of Small Molecules Interacting with RNA in Cellular and Preclinical Models

ACS chemical biology, 2021-07, Vol.16 (7), p.1111-1127

2021

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How We Think about Targeting RNA with Small Molecules

SP-0321: The British Institute of Radiology

The energy dissipation of a test-charge particle within a dense, degenerate electron- positron-ion plasma

Targeted Degradation of the Oncogenic MicroRNA 17-92 Cluster by Structure-Targeting Ligands

Assessment of safety and quality aspects of boiling treatment of quail eggs

Adaptive Radiotherapy Enabled by MRI Guidance

Image-guided Adaptive Radiotherapy for Bladder Cancer

Targeting the SARS-CoV‑2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders

Programming inactive RNA-binding small molecules into bioactive degraders

Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAs

A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype

Markers of optimal medical therapy are associated with improved limb outcomes after elective revascularization for intermittent claudication

Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions

Selective Small Molecule Recognition of RNA Base Pairs

Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera

A map of the SARS-CoV-2 RNA structurome

Diagnosis of Transthyretin Amyloid Cardiomyopathy

Hydrogels that listen to cells: a review of cell-responsive strategies in biomaterial design for tissue regeneration

Correlation of Clinician- and Patient-Reported Outcomes in the BC2001 Trial

Differences in Quality of Life and Toxicity for Male and Female Patients following Chemo(radiotherapy) for Bladder Cancer

Failing to Close the Gap Between Evidence and Clinical Practice in Radical Bladder Cancer Radiotherapy

Antibiotic resistance pattern and pathological features of avian pathogenic Escherichia coli O78:K80 in chickens

Unravelling the Phytochemical Composition and Antioxidant Potential of Different Parts of Rumex vesicarius L.: A RP-HPLC-MS-MS/MS, Chemometrics, and Molecular Docking-Based Comparative Study

Use of diffusion weighted-MRI (DW-MRI) as a prognostic biomarker of survival and time to cystectomy in muscle invasive bladder cancer (MIBC) following organ conserving treatment

Systematically Studying the Effect of Small Molecules Interacting with RNA in Cellular and Preclinical Models

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