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Recent Advances in Prostate Cancer Treatment and Drug Discovery

International journal of molecular sciences, 2018-05, Vol.19 (5), p.1359

2018

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From Omics to Multi-Omics Approaches for In-Depth Analysis of the Molecular Mechanisms of Prostate Cancer

International journal of molecular sciences, 2022-06, Vol.23 (11), p.6281

2022

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Targeting DNA Damage Response in Prostate and Breast Cancer

International journal of molecular sciences, 2020-11, Vol.21 (21), p.8273

2020

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Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4

Nature medicine, 2018-10, Vol.24 (10), p.1599-1610

2018

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Exploiting Epigenetic Alterations in Prostate Cancer

International journal of molecular sciences, 2017-05, Vol.18 (5), p.1017

2017

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Preclinical Anticipation of On- and Off-Target Resistance Mechanisms to Anti-Cancer Drugs: A Systematic Review

International journal of molecular sciences, 2024-01, Vol.25 (2), p.705

2024

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Addressing the Reciprocal Crosstalk between the AR and the PI3K/AKT/mTOR Signaling Pathways for Prostate Cancer Treatment

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2289

2023

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Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF

Journal of medicinal chemistry, 2016-02, Vol.59 (4), p.1642-1647

2016

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Darolutamide antagonizes androgen signaling by blocking enhancer and super‐enhancer activation

Molecular oncology, 2020-09, Vol.14 (9), p.2022-2039

2020

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Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents

Cell death & disease, 2016-09, Vol.7 (9), p.e2365-e2365

2016

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Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs

Expert opinion on therapeutic targets, 2016-07, Vol.20 (7), p.783-799

2016

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Enhanced Antitumor Efficacy of Radium-223 and Enzalutamide in the Intratibial LNCaP Prostate Cancer Model

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2189

2023

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Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma

British journal of haematology, 2017-09, Vol.178 (6), p.936-948

2017

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Comparative Proteomic and Transcriptomic Analysis of the Impact of Androgen Stimulation and Darolutamide Inhibition

Cancers, 2022-12, Vol.15 (1), p.2

2022

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The fate of the duplicated androgen receptor in fishes: a late neofunctionalization event?

BMC evolutionary biology, 2008-12, Vol.8, p.336

2008

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Characterization of the Menin-MLL Interaction as Therapeutic Cancer Target

Cancers, 2020-01, Vol.12 (1), p.201

2020

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Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis

Molecular oncology, 2024-03, Vol.18 (3), p.726-742

2024

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The potent AMPK inhibitor BAY-3827 shows strong efficacy in androgen-dependent prostate cancer models

Cellular oncology (Dordrecht), 2021-06, Vol.44 (3), p.581-594

2021

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Recent developments in antiandrogens and selective androgen receptor modulators

Molecular and cellular endocrinology, 2012-04, Vol.352 (1-2), p.79-91

2012

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The ubiquitin-specific protease USP10 modulates androgen receptor function

Molecular and cellular endocrinology, 2005-12, Vol.245 (1), p.138-146

2005

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BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients

Oncotarget, 2016-02, Vol.7 (5), p.6015-6028

2016

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Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models

International journal of cancer, 2019-09, Vol.145 (5), p.1382-1394

2019

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histone demethylase JARID1A regulates progesterone receptor expression

The FEBS journal, 2011-05, Vol.278 (9), p.1458-1469

2011

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Stimulation of N-Terminal Truncated Isoform of Androgen Receptor Stabilizes Human Ether-á-go-go-Related Gene-Encoded Potassium Channel Protein via Activation of Extracellular Signal Regulated Kinase 1/2

Endocrinology (Philadelphia), 2008-10, Vol.149 (10), p.5061-5069

2008

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New Androgen Response Elements in the Murine Pem Promoter Mediate Selective Transactivation

Molecular endocrinology (Baltimore, Md.), 2001-10, Vol.15 (10), p.1803-1816

2001

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Recent Advances in Prostate Cancer Treatment and Drug Discovery

From Omics to Multi-Omics Approaches for In-Depth Analysis of the Molecular Mechanisms of Prostate Cancer

Targeting DNA Damage Response in Prostate and Breast Cancer

Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4

Exploiting Epigenetic Alterations in Prostate Cancer

Preclinical Anticipation of On- and Off-Target Resistance Mechanisms to Anti-Cancer Drugs: A Systematic Review

Addressing the Reciprocal Crosstalk between the AR and the PI3K/AKT/mTOR Signaling Pathways for Prostate Cancer Treatment

Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF

Darolutamide antagonizes androgen signaling by blocking enhancer and super‐enhancer activation

Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents

Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs

Enhanced Antitumor Efficacy of Radium-223 and Enzalutamide in the Intratibial LNCaP Prostate Cancer Model

Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma

Comparative Proteomic and Transcriptomic Analysis of the Impact of Androgen Stimulation and Darolutamide Inhibition

The fate of the duplicated androgen receptor in fishes: a late neofunctionalization event?

Characterization of the Menin-MLL Interaction as Therapeutic Cancer Target

Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis

The potent AMPK inhibitor BAY-3827 shows strong efficacy in androgen-dependent prostate cancer models

Recent developments in antiandrogens and selective androgen receptor modulators

The ubiquitin-specific protease USP10 modulates androgen receptor function

BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients

Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models

histone demethylase JARID1A regulates progesterone receptor expression

Stimulation of N-Terminal Truncated Isoform of Androgen Receptor Stabilizes Human Ether-á-go-go-Related Gene-Encoded Potassium Channel Protein via Activation of Extracellular Signal Regulated Kinase 1/2

New Androgen Response Elements in the Murine Pem Promoter Mediate Selective Transactivation

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