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Validation and Stabilization of a Prophage Lysin of Clostridium perfringens by Using Yeast Surface Display and Coevolutionary Models

Applied and environmental microbiology, 2019-05, Vol.85 (10)

2019

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Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (18), p.e2219885120-e2219885120

2023

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Affibody-Indocyanine Green Based Contrast Agent for Photoacoustic and Fluorescence Molecular Imaging of B7–H3 Expression in Breast Cancer

Bioconjugate chemistry, 2019-06, Vol.30 (6), p.1677-1689

2019

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Fine Epitope Mapping of the CD19 Extracellular Domain Promotes Design

Biochemistry (Easton), 2019-12, Vol.58 (48), p.4869-4881

2019

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High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin Domains

PloS one, 2015-09, Vol.10 (9), p.e0138956

2015

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Picomolar Affinity Fibronectin Domains Engineered Utilizing Loop Length Diversity, Recursive Mutagenesis, and Loop Shuffling

Journal of molecular biology, 2008-09, Vol.381 (5), p.1238-1252

2008

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Anti-CD19 CAR T cells potently redirected to kill solid tumor cells

PloS one, 2021-03, Vol.16 (3), p.e0247701-e0247701

2021

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Geometry and expression enhance enrichment of functional yeast-displayed ligands via cell panning

Biotechnology and bioengineering, 2016-11, Vol.113 (11), p.2328-2341

2016

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Stability and CDR Composition Biases Enrich Binder Functionality Landscapes

Journal of molecular biology, 2010-08, Vol.401 (1), p.84-96

2010

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Sequence-activity mapping via depletion reveals striking mutational tolerance and elucidates functional motifs in Tur1a antimicrobial peptide

Protein engineering, design and selection, 2024-01, Vol.37

2024

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Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers

Skeletal muscle, 2023-05, Vol.13 (1), p.9-9, Article 9

2023

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Determinants of Developability and Evolvability of Synthetic Miniproteins as Ligand Scaffolds

Journal of molecular biology, 2023-12, Vol.435 (24), p.168339-168339, Article 168339

2023

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Molecular homing and retention of muscle membrane stabilizing copolymers by non-invasive optical imaging in vivo

Molecular therapy. Methods & clinical development, 2023-03, Vol.28, p.162-176

2023

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Protein Engineering and High‐Throughput Screening by Yeast Surface Display: Survey of Current Methods

Small science, 2023-12, Vol.3 (12), p.n/a

2023

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Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury

JACC. Basic to translational science, 2019-04, Vol.4 (2), p.275-287

2019

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Improved mutant function prediction via PACT: Protein Analysis and Classifier Toolkit

Bioinformatics (Oxford, England), 2019-08, Vol.35 (16), p.2707-2712

2019

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Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density

Journal of the American Chemical Society, 2019-01, Vol.141 (1), p.251-261

2019

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Mining and Statistical Modeling of Natural and Variant Class IIa Bacteriocins Elucidate Activity and Selectivity Profiles across Species

Applied and environmental microbiology, 2020-10, Vol.86 (22)

2020

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Protein engineering via sequence-performance mapping

Cell systems, 2023-08, Vol.14 (8), p.656-666

2023

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Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization

Protein engineering, design and selection, 2024-01, Vol.37

2024

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Affibody-mediated controlled release of fibroblast growth factor 2

Journal of controlled release, 2022-10, Vol.350, p.815-828

2022

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Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds

Molecular cancer therapeutics, 2017-07, Vol.16 (7), p.1324-1334

2017

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Effect of Bottlebrush Poloxamer Architecture on Binding to Liposomes

Biomacromolecules, 2023-01, Vol.24 (1), p.449-461

2023

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Engineered protein-small molecule conjugates empower selective enzyme inhibition

Cell chemical biology, 2022-02, Vol.29 (2), p.328-338.e4

2022

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Photoacoustic lifetime contrast between methylene blue monomers and self-quenched dimers as a model for dual-labeled activatable probes

Journal of biomedical optics, 2013-05, Vol.18 (5), p.056004-056004

2013

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Validation and Stabilization of a Prophage Lysin of Clostridium perfringens by Using Yeast Surface Display and Coevolutionary Models

Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts

Affibody-Indocyanine Green Based Contrast Agent for Photoacoustic and Fluorescence Molecular Imaging of B7–H3 Expression in Breast Cancer

Fine Epitope Mapping of the CD19 Extracellular Domain Promotes Design

High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin Domains

Picomolar Affinity Fibronectin Domains Engineered Utilizing Loop Length Diversity, Recursive Mutagenesis, and Loop Shuffling

Anti-CD19 CAR T cells potently redirected to kill solid tumor cells

Geometry and expression enhance enrichment of functional yeast-displayed ligands via cell panning

Stability and CDR Composition Biases Enrich Binder Functionality Landscapes

Sequence-activity mapping via depletion reveals striking mutational tolerance and elucidates functional motifs in Tur1a antimicrobial peptide

Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers

Determinants of Developability and Evolvability of Synthetic Miniproteins as Ligand Scaffolds

Molecular homing and retention of muscle membrane stabilizing copolymers by non-invasive optical imaging in vivo

Protein Engineering and High‐Throughput Screening by Yeast Surface Display: Survey of Current Methods

Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury

Improved mutant function prediction via PACT: Protein Analysis and Classifier Toolkit

Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density

Mining and Statistical Modeling of Natural and Variant Class IIa Bacteriocins Elucidate Activity and Selectivity Profiles across Species

Protein engineering via sequence-performance mapping

Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization

Affibody-mediated controlled release of fibroblast growth factor 2

Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds

Effect of Bottlebrush Poloxamer Architecture on Binding to Liposomes

Engineered protein-small molecule conjugates empower selective enzyme inhibition

Photoacoustic lifetime contrast between methylene blue monomers and self-quenched dimers as a model for dual-labeled activatable probes

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