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The Effects of Propranolol on Acute Hypertension of Anesthetized Dogs and on the Carotid Sinus Reflex Responses of Anesthetized and Awake Dogs

Circulation research, 1977-08, Vol.41 (2), p.179-186

1977

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CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression

Nature biotechnology, 2008-05, Vol.26 (5), p.549-551

2008

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Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung

Gene therapy, 2011-10, Vol.18 (10), p.996-1005

2011

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A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial

American journal of respiratory and critical care medicine, 2015-12, Vol.192 (11), p.1389-1392

2015

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Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene Therapy

American journal of respiratory and critical care medicine, 2012-11, Vol.186 (9), p.846-856

2012

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Sendai virus-mediated CFTR gene transfer to the airway epithelium

Gene therapy, 2007-10, Vol.14 (19), p.1371-1379

2007

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The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins

Gene therapy, 2018-08, Vol.25 (5), p.345-358

2018

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Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung

Gene therapy, 2014-01, Vol.21 (1), p.89-95

2014

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Genetic medicines for CF: Hype versus reality

Pediatric pulmonology, 2016-10, Vol.51 (S44), p.S5-S17

2016

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A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis

Thorax, 2013-11, Vol.68 (11), p.1075-1077

2013

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Correction of a chronic pulmonary disease through lentiviral vector-mediated protein expression

Molecular therapy. Methods & clinical development, 2022-06, Vol.25, p.382-391

2022

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Gene therapy progress and prospects: cystic fibrosis

Gene therapy, 2006-07, Vol.13 (14), p.1061-1067

2006

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Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer

Biomaterials, 2011-04, Vol.32 (10), p.2614-2624

2011

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Enhanced Lung Gene Expression After Aerosol Delivery of Concentrated pDNA/PEI Complexes

Molecular therapy, 2008-07, Vol.16 (7), p.1283-1290

2008

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Identification and Functional Characterization of Cytoplasmic Determinants of Plasmid DNA Nuclear Import

The Journal of biological chemistry, 2009-09, Vol.284 (39), p.26978-26987

2009

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Keratinocyte growth factor therapy in murine oleic acid-induced acute lung injury

American journal of physiology. Lung cellular and molecular physiology, 2005-06, Vol.288 (6), p.L1179-L1192

2005

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Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

Respiratory research, 2006-02, Vol.7 (1), p.26-26, Article 26

2006

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597: Protocol development for mouse toxicology studies using lentiviral gene therapy

Journal of cystic fibrosis, 2021-11, Vol.20, p.S284

2021

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The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways

Biomaterials, 2010-03, Vol.31 (9), p.2665-2672

2010

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P046 Lenticlair™-ON: An extension trial examining long-term safety and efficacy outcomes associated with an inhaled F/HN-pseudotyped lentiviral vector for CF gene therapy in people with cystic fibrosis

Journal of cystic fibrosis, 2024-06, Vol.23, p.S80-S80

2024

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P045 Lenticlair™ 1: A phase 1/2 trial evaluating the safety, tolerability and efficacy of an inhaled F/HN-pseudotyped lentiviral vector for CF gene therapy in people with CF ineligible for CFTR modulators

Journal of cystic fibrosis, 2024-06, Vol.23, p.S80-S80

2024

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The Effects of Propranolol on Acute Hypertension of Anesthetized Dogs and on the Carotid Sinus Reflex Responses of Anesthetized and Awake Dogs

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression

Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung

Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial

Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene Therapy

Sendai virus-mediated CFTR gene transfer to the airway epithelium

The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins

Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung

Genetic medicines for CF: Hype versus reality

A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis

Correction of a chronic pulmonary disease through lentiviral vector-mediated protein expression

Gene therapy progress and prospects: cystic fibrosis

The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep

Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer

Enhanced Lung Gene Expression After Aerosol Delivery of Concentrated pDNA/PEI Complexes

Identification and Functional Characterization of Cytoplasmic Determinants of Plasmid DNA Nuclear Import

Keratinocyte growth factor therapy in murine oleic acid-induced acute lung injury

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

597: Protocol development for mouse toxicology studies using lentiviral gene therapy

Pharmacological and pre-clinical safety profile of rSIV.F/HN, a hybrid lentiviral vector for cystic fibrosis gene therapy

The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways

P046 Lenticlair™-ON: An extension trial examining long-term safety and efficacy outcomes associated with an inhaled F/HN-pseudotyped lentiviral vector for CF gene therapy in people with cystic fibrosis

P045 Lenticlair™ 1: A phase 1/2 trial evaluating the safety, tolerability and efficacy of an inhaled F/HN-pseudotyped lentiviral vector for CF gene therapy in people with CF ineligible for CFTR modulators

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