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Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57 Bl6 mice

Molecular psychiatry, 2008-05, Vol.13 (5), p.498-506

2008

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Expression of D-serine and glycine transporters in the prefrontal cortex and cerebellum in schizophrenia

Schizophrenia research, 2008-07, Vol.102 (1), p.283-294

2008

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CNS Target Identification and Validation: Avoiding the Valley of Death or Naive Optimism?

Annual review of pharmacology and toxicology, 2017-01, Vol.57 (1), p.171-187

2017

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Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests ‘anxiolytic’ effects are mediated by different mechanisms

Psychopharmacologia, 2009-06, Vol.204 (3), p.499-509

2009

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Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption

Journal of psychopharmacology (Oxford), 2009-07, Vol.23 (5), p.475-486

2009

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Behavioral and biochemical characterization of a mutant mouse strain lacking d-amino acid oxidase activity and its implications for schizophrenia

Molecular and cellular neuroscience, 2006-08, Vol.32 (4), p.324-334

2006

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The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor

Neuropharmacology, 2003-06, Vol.44 (8), p.1031-1037

2003

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Current and Novel Approaches to the Drug Treatment of Schizophrenia

Journal of medicinal chemistry, 2001-02, Vol.44 (4), p.477-501

2001

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Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers

Journal of psychopharmacology (Oxford), 2009-07, Vol.23 (5), p.487-494

2009

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Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats

Psychopharmacologia, 2008-05, Vol.197 (4), p.591-600

2008

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Modulation of [ 3H]MK-801 binding to NMDA receptors in vivo and in vitro

European journal of pharmacology, 2000-06, Vol.397 (2), p.263-270

2000

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Determination of guinea-pig cortical γ-secretase activity ex vivo following the systemic administration of a γ-secretase inhibitor

Neuropharmacology, 2005-06, Vol.48 (7), p.1002-1011

2005

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Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression

Neuropharmacology, 2005-03, Vol.48 (4), p.492-502

2005

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Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT2C receptor responsivity

Neuropharmacology, 2003-03, Vol.44 (4), p.439-448

2003

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The glycine/NMDA receptor antagonist, R‐(+)‐HA‐966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK‐801) in rodents

British journal of pharmacology, 1993-04, Vol.108 (4), p.1156-1163

1993

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Hippocampal 5-HT synthesis and release in vivo is decreased by infusion of 8-OHDPAT into the nucleus raphe dorsalis

Neuroscience letters, 1989-05, Vol.100 (1), p.276-280

1989

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Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57/BI6 mice

Molecular psychiatry, 2008-05, Vol.13 (5), p.498-506

2008

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Enantiomers of HA-966 (3-Amino-1-Hydroxypyrrolid-2-One) Exhibit Distinct Central Nervous System Effects: (+)-HA-966 is a Selective Glycine/N- Methyl-D-Aspartate Receptor Antagonist, But (-)-HA-966 is a Potent γ-Butyrolactone-Like Sedative

Proceedings of the National Academy of Sciences - PNAS, 1990-01, Vol.87 (1), p.347-351

1990

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Increased density of glutamate/ N-methyl- d-aspartate receptors in putamen from schizophrenic patients

Neuroscience letters, 1998-01, Vol.241 (2), p.143-146

1998

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Neurochemical and behavioural evidence for mediation of the hyperphagic action of 8-OH-DPAT by 5-HT cell body autoreceptors

European journal of pharmacology, 1986-10, Vol.129 (3), p.347-352

1986

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Low doses of the putative serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicit feeding in the rat

Psychopharmacologia, 1985-01, Vol.86 (1-2), p.197-204

1985

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Deficits of NMDA receptors and glutamate uptake sites in the frontal cortex in AIDS

Neuroreport, 1999-11, Vol.10 (17), p.3513-3515

1999

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Competitive and Glycine/NMDA Receptor Antagonists Attenuate Withdrawal-induced Behaviours and Increased Hippocampal Acetylcholine Efflux in Morphine-dependent Rats

Neuropharmacology, 1997-02, Vol.36 (2), p.241-250

1997

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R‐(+)‐HA‐966, a glycine/NMDA receptor antagonist, selectively blocks the activation of the mesolimbic dopamine system by amphetamine

British journal of pharmacology, 1991-08, Vol.103 (4), p.2037-2044

1991

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Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57 Bl6 mice

Expression of D-serine and glycine transporters in the prefrontal cortex and cerebellum in schizophrenia

CNS Target Identification and Validation: Avoiding the Valley of Death or Naive Optimism?

Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests ‘anxiolytic’ effects are mediated by different mechanisms

Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption

Behavioral and biochemical characterization of a mutant mouse strain lacking d-amino acid oxidase activity and its implications for schizophrenia

The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor

Current and Novel Approaches to the Drug Treatment of Schizophrenia

Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers

The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents

Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats

Modulation of [ 3H]MK-801 binding to NMDA receptors in vivo and in vitro

Determination of guinea-pig cortical γ-secretase activity ex vivo following the systemic administration of a γ-secretase inhibitor

Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression

Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT2C receptor responsivity

The glycine/NMDA receptor antagonist, R‐(+)‐HA‐966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK‐801) in rodents

Hippocampal 5-HT synthesis and release in vivo is decreased by infusion of 8-OHDPAT into the nucleus raphe dorsalis

Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57/BI6 mice

Enantiomers of HA-966 (3-Amino-1-Hydroxypyrrolid-2-One) Exhibit Distinct Central Nervous System Effects: (+)-HA-966 is a Selective Glycine/N- Methyl-D-Aspartate Receptor Antagonist, But (-)-HA-966 is a Potent γ-Butyrolactone-Like Sedative

Increased density of glutamate/ N-methyl- d-aspartate receptors in putamen from schizophrenic patients

Neurochemical and behavioural evidence for mediation of the hyperphagic action of 8-OH-DPAT by 5-HT cell body autoreceptors

Low doses of the putative serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicit feeding in the rat

Deficits of NMDA receptors and glutamate uptake sites in the frontal cortex in AIDS

Competitive and Glycine/NMDA Receptor Antagonists Attenuate Withdrawal-induced Behaviours and Increased Hippocampal Acetylcholine Efflux in Morphine-dependent Rats

R‐(+)‐HA‐966, a glycine/NMDA receptor antagonist, selectively blocks the activation of the mesolimbic dopamine system by amphetamine

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