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ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases

The Journal of biological chemistry, 2009-07, Vol.284 (31), p.20447-20451

2009

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KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury

American journal of physiology. Renal physiology, 2021-08, Vol.321 (2), p.F135-F148

2021

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Epithelial Sodium Channels Are Activated by Furin-dependent Proteolysis

The Journal of biological chemistry, 2004-04, Vol.279 (18), p.18111-18114

2004

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Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition

American journal of physiology. Renal physiology, 2006-06, Vol.290 (6), p.F1488-F1496

2006

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Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury

Antioxidants, 2022-09, Vol.11 (9), p.1810

2022

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Muc1 is protective during kidney ischemia-reperfusion injury

American journal of physiology. Renal physiology, 2015-06, Vol.308 (12), p.F1452-F1462

2015

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Distinct Pools of Epithelial Sodium Channels Are Expressed at the Plasma Membrane

The Journal of biological chemistry, 2004-11, Vol.279 (47), p.48491-48494

2004

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Sialylation of N-linked glycans mediates apical delivery of endolyn in MDCK cells via a galectin-9-dependent mechanism

Molecular biology of the cell, 2012-09, Vol.23 (18), p.3636-3646

2012

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Mice lacking γENaC palmitoylation sites maintain benzamil-sensitive Na+ transport despite reduced channel activity

JCI insight, 2023-11, Vol.8 (21)

2023

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Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel

American Journal of Physiology - Renal Physiology, 2010-10, Vol.299 (4), p.F854-F861

2010

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Role of N- and O-glycans in polarized biosynthetic sorting

American Journal of Physiology: Cell Physiology, 2006-01, Vol.290 (1), p.C1-C10

2006

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Trial of Amiloride in Type 2 Diabetes with Proteinuria

Kidney international reports, 2017-09, Vol.2 (5), p.893-904

2017

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Functional Role of Extracellular Loop Cysteine Residues of the Epithelial Na+ Channel in Na+ Self-inhibition

The Journal of biological chemistry, 2007-07, Vol.282 (28), p.20180-20190

2007

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Role of Epithelial Sodium Channels and Their Regulators in Hypertension

The Journal of biological chemistry, 2010-10, Vol.285 (40), p.30363-30369

2010

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ENaC regulation by proteases and shear stress

Current molecular pharmacology, 2013-03, Vol.6 (1), p.28

2013

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Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells

American journal of physiology. Renal physiology, 2011-09, Vol.301 (3), p.F622-F633

2011

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RNA-seq analysis of glycosylation related gene expression in STZ-induced diabetic rat kidney inner medulla

Frontiers in physiology, 2015-10, Vol.6, p.274-274

2015

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Multiple Biosynthetic Trafficking Routes for Apically Secreted Proteins in MDCK Cells

Traffic (Copenhagen, Denmark), 2012-03, Vol.13 (3), p.433-442

2012

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MUC1 membrane trafficking: protocols for assessing biosynthetic delivery, endocytosis, recycling, and release through exosomes

Methods in molecular biology (Clifton, N.J.), 2012-01, Vol.842, p.123

2012

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Influence of glycoprotein MUC1 on trafficking of the Ca2+-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis

The Journal of biological chemistry, 2023-03, Vol.299 (3), p.102925-102925, Article 102925

2023

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Proteolytic Processing of the Epithelial Sodium Channel γ Subunit Has a Dominant Role in Channel Activation

The Journal of biological chemistry, 2008-09, Vol.283 (37), p.25290-25295

2008

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Recycling of MUC1 Is Dependent on Its Palmitoylation

The Journal of biological chemistry, 2006-04, Vol.281 (17), p.12112-12122

2006

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Plasmin Activates Epithelial Na+ Channels by Cleaving the γ Subunit

The Journal of biological chemistry, 2008-12, Vol.283 (52), p.36586-36591

2008

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Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation state

Molecular biology of the cell, 2000-03, Vol.11 (3), p.819-831

2000

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The Role of MUC1 in Lactation‐Associated Bone Mineral Conservation

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases

KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury

Epithelial Sodium Channels Are Activated by Furin-dependent Proteolysis

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition

Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury

Muc1 is protective during kidney ischemia-reperfusion injury

Distinct Pools of Epithelial Sodium Channels Are Expressed at the Plasma Membrane

Sialylation of N-linked glycans mediates apical delivery of endolyn in MDCK cells via a galectin-9-dependent mechanism

Mice lacking γENaC palmitoylation sites maintain benzamil-sensitive Na+ transport despite reduced channel activity

Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel

Role of N- and O-glycans in polarized biosynthetic sorting

Trial of Amiloride in Type 2 Diabetes with Proteinuria

Functional Role of Extracellular Loop Cysteine Residues of the Epithelial Na+ Channel in Na+ Self-inhibition

Role of Epithelial Sodium Channels and Their Regulators in Hypertension

ENaC regulation by proteases and shear stress

Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells

RNA-seq analysis of glycosylation related gene expression in STZ-induced diabetic rat kidney inner medulla

Multiple Biosynthetic Trafficking Routes for Apically Secreted Proteins in MDCK Cells

MUC1 membrane trafficking: protocols for assessing biosynthetic delivery, endocytosis, recycling, and release through exosomes

Influence of glycoprotein MUC1 on trafficking of the Ca2+-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis

Proteolytic Processing of the Epithelial Sodium Channel γ Subunit Has a Dominant Role in Channel Activation

Recycling of MUC1 Is Dependent on Its Palmitoylation

Plasmin Activates Epithelial Na+ Channels by Cleaving the γ Subunit

Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation state

The Role of MUC1 in Lactation‐Associated Bone Mineral Conservation

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