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Clinical Pharmacokinetics and Pharmacodynamics of Bosutinib

Clinical pharmacokinetics, 2016-10, Vol.55 (10), p.1191-1204

2016

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Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug-Drug and Drug-Disease Interactions

Drug metabolism and disposition, 2017-04, Vol.45 (4), p.390-398

2017

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Effect of bosutinib on the absorption of dabigatran etexilate mesylate, a P-glycoprotein substrate, in healthy subjects

European journal of clinical pharmacology, 2017-01, Vol.73 (1), p.57-63

2017

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Absolute Bioavailability of Bosutinib in Healthy Subjects From an Open‐Label, Randomized, 2‐Period Crossover Study

Clinical pharmacology in drug development, 2018-05, Vol.7 (4), p.373-381

2018

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Effect of aprepitant, a moderate CYP3A4 inhibitor, on bosutinib exposure in healthy subjects

European journal of clinical pharmacology, 2017, Vol.73 (1), p.49-56

2017

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Population Pharmacokinetic and Pharmacodynamic Analysis of Bosutinib

DRUG METABOLISM AND PHARMACOKINETICS, 2014, Vol.29 (6), p.441-448

2014

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Phase I Study of Bosutinib, a Src/Abl Tyrosine Kinase Inhibitor, Administered to Patients with Advanced Solid Tumors

Clinical cancer research, 2012-02, Vol.18 (4), p.1092-1100

2012

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Pharmacokinetic–pharmacodynamic relationship of bosutinib in patients with chronic phase chronic myeloid leukemia

Cancer chemotherapy and pharmacology, 2013, Vol.71 (1), p.209-218

2013

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Safety profile and pharmacokinetic analyses of the anti-CTLA4 antibody tremelimumab administered as a one hour infusion

Journal of translational medicine, 2012-11, Vol.10 (1), p.236-236, Article 236

2012

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Phase II, Randomized, Double-Blind, Placebo-Controlled Studies of Ruprintrivir Nasal Spray 2-Percent Suspension for Prevention and Treatment of Experimentally Induced Rhinovirus Colds in Healthy Volunteers

Antimicrobial Agents and Chemotherapy, 2003-12, Vol.47 (12), p.3907-3916

2003

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Pharmacokinetics of Nelfinavir in Subjects With Hepatic Impairment

Journal of clinical pharmacology, 2006-11, Vol.46 (11), p.1241-1249

2006

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Pharmacokinetic Interactions between Nelfinavir and 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Atorvastatin and Simvastatin

Antimicrobial Agents and Chemotherapy, 2001-12, Vol.45 (12), p.3445-3450

2001

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Pharmacokinetics of Bupropion and its Metabolites in Cigarette Smokers versus Nonsmokers

Journal of clinical pharmacology, 1997-08, Vol.37 (8), p.737-743

1997

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Pharmacokinetics and Safety of an Antirhinoviral Agent, Ruprintrivir, in Healthy Volunteers

Antimicrobial Agents and Chemotherapy, 2002-02, Vol.46 (2), p.392-397

2002

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Pharmacokinetic interaction of nelfinavir and methadone in intravenous drug users

Biopharmaceutics & drug disposition, 2006-03, Vol.27 (2), p.61-68

2006

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The Application of Accelerator Mass Spectrometry to Absolute Bioavailability Studies in Humans: Simultaneous Administration of an Intravenous Microdose of 14C-Nelfinavir Mesylate Solution and Oral Nelfinavir to Healthy Volunteers

Journal of clinical pharmacology, 2005-10, Vol.45 (10), p.1198-1205

2005

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Clinical Evaluation of the Nelfinavir-Rifabutin Interaction in Patients with Tuberculosis and Human Immunodeficiency Virus Infection

Pharmacotherapy, 2007-06, Vol.27 (6), p.793-800

2007

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RETRACTED: Population Pharmacokinetic and Pharmacodynamic Analysis of Bosutinib

Drug metabolism and pharmacokinetics, 2014, Vol.29 (6), p.441-448

2014

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Pharmacokinetics and Tolerability of Bosutinib in Asian Versus Non-Asian Patients with Philadelphia Chromosome–Positive Leukemia

Blood, 2012-11, Vol.120 (21), p.4440-4440

2012

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Lack of Effect of Cimetidine on the Pharmacokinetics of Sustained-Release Bupropion

Journal of clinical pharmacology, 1999-11, Vol.39 (11), p.1184-1188

1999

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Pharmacokinetics of Amiloride after Inhalation and Oral Administration in Adolescents and Adults with Cystic Fibrosis

Pharmacotherapy, 1997-03, Vol.17 (2), p.263-270

1997

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Pharmacodynamic Analysis of Bosutinib in Patients with Chronic Myelogenous Leukemia

Blood, 2011-11, Vol.118 (21), p.3778-3778

2011

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Abstract A195: A population pharmacokinetic (PPK) model of bosutinib (BOS)

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.A195-A195

2011

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Mechanism of intestinal absorption of ranitidine and ondansetron : transport across caco-2 cell monolayers

Pharmaceutical research, 1993-12, Vol.10 (12), p.1722-1725

1993

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Erratum to: Pharmacokinetic–pharmacodynamic relationship of bosutinib in patients with chronic-phase chronic myeloid leukemia

Cancer chemotherapy and pharmacology, 2013-04, Vol.71 (4), p.1105-1106

2013

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Clinical Pharmacokinetics and Pharmacodynamics of Bosutinib

Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug-Drug and Drug-Disease Interactions

Effect of bosutinib on the absorption of dabigatran etexilate mesylate, a P-glycoprotein substrate, in healthy subjects

Absolute Bioavailability of Bosutinib in Healthy Subjects From an Open‐Label, Randomized, 2‐Period Crossover Study

Effect of aprepitant, a moderate CYP3A4 inhibitor, on bosutinib exposure in healthy subjects

Population Pharmacokinetic and Pharmacodynamic Analysis of Bosutinib

Phase I Study of Bosutinib, a Src/Abl Tyrosine Kinase Inhibitor, Administered to Patients with Advanced Solid Tumors

Pharmacokinetic–pharmacodynamic relationship of bosutinib in patients with chronic phase chronic myeloid leukemia

Safety profile and pharmacokinetic analyses of the anti-CTLA4 antibody tremelimumab administered as a one hour infusion

Phase II, Randomized, Double-Blind, Placebo-Controlled Studies of Ruprintrivir Nasal Spray 2-Percent Suspension for Prevention and Treatment of Experimentally Induced Rhinovirus Colds in Healthy Volunteers

Pharmacokinetics of Nelfinavir in Subjects With Hepatic Impairment

Pharmacokinetic Interactions between Nelfinavir and 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Atorvastatin and Simvastatin

Pharmacokinetics of Bupropion and its Metabolites in Cigarette Smokers versus Nonsmokers

Pharmacokinetics and Safety of an Antirhinoviral Agent, Ruprintrivir, in Healthy Volunteers

Pharmacokinetic interaction of nelfinavir and methadone in intravenous drug users

The Application of Accelerator Mass Spectrometry to Absolute Bioavailability Studies in Humans: Simultaneous Administration of an Intravenous Microdose of 14C-Nelfinavir Mesylate Solution and Oral Nelfinavir to Healthy Volunteers

Clinical Evaluation of the Nelfinavir-Rifabutin Interaction in Patients with Tuberculosis and Human Immunodeficiency Virus Infection

RETRACTED: Population Pharmacokinetic and Pharmacodynamic Analysis of Bosutinib

Pharmacokinetics and Tolerability of Bosutinib in Asian Versus Non-Asian Patients with Philadelphia Chromosome–Positive Leukemia

Lack of Effect of Cimetidine on the Pharmacokinetics of Sustained-Release Bupropion

Pharmacokinetics of Amiloride after Inhalation and Oral Administration in Adolescents and Adults with Cystic Fibrosis

Pharmacodynamic Analysis of Bosutinib in Patients with Chronic Myelogenous Leukemia

Abstract A195: A population pharmacokinetic (PPK) model of bosutinib (BOS)

Mechanism of intestinal absorption of ranitidine and ondansetron : transport across caco-2 cell monolayers

Erratum to: Pharmacokinetic–pharmacodynamic relationship of bosutinib in patients with chronic-phase chronic myeloid leukemia

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