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Bone metastasis: Interaction between cancer cells and bone microenvironment

Journal of oral biosciences, 2019-06, Vol.61 (2), p.95-98

Hiraga, Toru

2019

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Hypoxic Microenvironment and Metastatic Bone Disease

International journal of molecular sciences, 2018-11, Vol.19 (11), p.3523

Hiraga, Toru

2018

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Targeted Agents in Preclinical and Early Clinical Development for the Treatment of Cancer Bone Metastases

Expert opinion on investigational drugs, 2016-03, Vol.25 (3), p.319-334

Hiraga, Toru

2016

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Cancer Stem-like Cell Marker CD44 Promotes Bone Metastases by Enhancing Tumorigenicity, Cell Motility, and Hyaluronan Production

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (13), p.4112-4122

2013

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Establishment and characterization of a C57BL/6 mouse model of bone metastasis of breast cancer

Journal of bone and mineral metabolism, 2019-03, Vol.37 (2), p.235-242

2019

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Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases

Molecular cancer research, 2021-12, Vol.19 (12), p.2110-2119

2021

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Crosstalk between cancer cells and bone microenvironment in bone metastasis

Biochemical and biophysical research communications, 2005-03, Vol.328 (3), p.679-687

2005

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Decreased sensory nerve excitation and bone pain associated with mouse Lewis lung cancer in TRPV1-deficient mice

Journal of bone and mineral metabolism, 2018-05, Vol.36 (3), p.274-285

2018

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Immunotherapy targeting PD‑1/PD‑L1: A potential approach for the treatment of cancer bone metastases (Review)

International journal of oncology, 2024-04, Vol.64 (4)

Hiraga, Toru

2024

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Zoledronic acid delays wound healing of the tooth extraction socket, inhibits oral epithelial cell migration, and promotes proliferation and adhesion to hydroxyapatite of oral bacteria, without causing osteonecrosis of the jaw, in mice

Journal of bone and mineral metabolism, 2010-03, Vol.28 (2), p.165-175

2010

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Bone‐targeting phospholipid polymers to solubilize the lipophilic anticancer drug

Journal of biomedical materials research. Part A, 2020-10, Vol.108 (10), p.2090-2099

2020

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Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer

Cancer research (Chicago, Ill.), 2007-05, Vol.67 (9), p.4157-4163

2007

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Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor‐Marked Stromal Population from Adipogenic to Osteoblastic Lineage

Journal of bone and mineral research, 2019-10, Vol.34 (10), p.1952-1963

2019

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Expression and localization of CRAMP in rat tooth germ and during reparative dentin formation

Clinical oral investigations, 2018-09, Vol.22 (7), p.2559-2566

2018

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Imatinib mesylate suppresses bone metastases of breast cancer by inhibiting osteoclasts through the blockade of c‐Fms signals

International journal of cancer, 2009-01, Vol.124 (1), p.215-222

2009

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Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy

Scientific reports, 2017-07, Vol.7 (1), p.4928-11, Article 4928

2017

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Comparable roles of CD44v8-10 and CD44s in the development of bone metastases in a mouse model

Oncology letters, 2016-10, Vol.12 (4), p.2962-2969

2016

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Altered immunolocalization of FGF23 in murine femora metastasized with human breast carcinoma MDA-MB-231 cells

Journal of bone and mineral metabolism, 2021-09, Vol.39 (5), p.810-823

2021

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Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases

Cancer research (Chicago, Ill.), 2012-08, Vol.72 (16), p.4238-4249

2012

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Acid activation of Trpv1 leads to an up-regulation of calcitonin gene-related peptide expression in dorsal root ganglion neurons via the CaMK-CREB cascade: a potential mechanism of inflammatory pain

Molecular biology of the cell, 2010-08, Vol.21 (15), p.2568-2577

2010

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Differentiation by NK cells is a prerequisite for effective targeting of cancer stem cells/poorly differentiated tumors by chemopreventive and chemotherapeutic drugs

Journal of Cancer, 2017-01, Vol.8 (4), p.537-554

2017

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Zoledronic Acid Inhibits Visceral Metastases in the 4T1/luc Mouse Breast Cancer Model

Clinical cancer research, 2004-07, Vol.10 (13), p.4559-4567

2004

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Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

The Journal of clinical investigation, 2004-08, Vol.114 (4), p.475-484

2004

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Acidic microenvironment created by osteoclasts causes bone pain associated with tumor colonization

Journal of bone and mineral metabolism, 2007-03, Vol.25 (2), p.99-104

2007

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Bone metastasis: Interaction between cancer cells and bone microenvironment

Hypoxic Microenvironment and Metastatic Bone Disease

Targeted Agents in Preclinical and Early Clinical Development for the Treatment of Cancer Bone Metastases

Cancer Stem-like Cell Marker CD44 Promotes Bone Metastases by Enhancing Tumorigenicity, Cell Motility, and Hyaluronan Production

Establishment and characterization of a C57BL/6 mouse model of bone metastasis of breast cancer

Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases

Crosstalk between cancer cells and bone microenvironment in bone metastasis

Decreased sensory nerve excitation and bone pain associated with mouse Lewis lung cancer in TRPV1-deficient mice

Immunotherapy targeting PD‑1/PD‑L1: A potential approach for the treatment of cancer bone metastases (Review)

Zoledronic acid delays wound healing of the tooth extraction socket, inhibits oral epithelial cell migration, and promotes proliferation and adhesion to hydroxyapatite of oral bacteria, without causing osteonecrosis of the jaw, in mice

Bone‐targeting phospholipid polymers to solubilize the lipophilic anticancer drug

Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer

Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor‐Marked Stromal Population from Adipogenic to Osteoblastic Lineage

Expression and localization of CRAMP in rat tooth germ and during reparative dentin formation

Imatinib mesylate suppresses bone metastases of breast cancer by inhibiting osteoclasts through the blockade of c‐Fms signals

Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy

Comparable roles of CD44v8-10 and CD44s in the development of bone metastases in a mouse model

Altered immunolocalization of FGF23 in murine femora metastasized with human breast carcinoma MDA-MB-231 cells

Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases

Acid activation of Trpv1 leads to an up-regulation of calcitonin gene-related peptide expression in dorsal root ganglion neurons via the CaMK-CREB cascade: a potential mechanism of inflammatory pain

Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial

Differentiation by NK cells is a prerequisite for effective targeting of cancer stem cells/poorly differentiated tumors by chemopreventive and chemotherapeutic drugs

Zoledronic Acid Inhibits Visceral Metastases in the 4T1/luc Mouse Breast Cancer Model

Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

Acidic microenvironment created by osteoclasts causes bone pain associated with tumor colonization

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