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Constraining Cyclic Peptides To Mimic Protein Structure Motifs

Angewandte Chemie (International ed.), 2014-11, Vol.53 (48), p.13020-13041

International ed. in English, 2014

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Connecting Hydrophobic Surfaces in Cyclic Peptides Increases Membrane Permeability

Angewandte Chemie International Edition, 2021-04, Vol.60 (15), p.8385-8390

International ed. in English, 2021

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Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable

Angewandte Chemie (International ed.), 2014-11, Vol.53 (45), p.12059-12063

International ed. in English, 2014

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Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides

Chembiochem : a European journal of chemical biology, 2015-11, Vol.16 (16), p.2289-2293

2015

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Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (26), p.11686-11691

2010

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Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities

Chemical communications (Cambridge, England), 2019, Vol.55 (89), p.13362-13365

2019

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Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages

Journal of innate immunity, 2023-01, Vol.15 (1), p.468-484

2023

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Inhibition of Dynamin Mediated Endocytosis by the DynolesSynthesis and Functional Activity of a Family of Indoles

Journal of medicinal chemistry, 2009-06, Vol.52 (12), p.3762-3773

2009

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Truncated and helix-constrained peptides with high affinity and specificity for the cFos coiled-coil of AP-1

PloS one, 2013-03, Vol.8 (3), p.e59415-e59415

2013

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Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis

Microbiology spectrum, 2023-08, Vol.11 (4), p.e0046523-e0046523

2023

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Crystal Structures of Protein-Bound Cyclic Peptides

Chemical reviews, 2019-09, Vol.119 (17), p.9861-9914

2019

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Iminochromene Inhibitors of Dynamins I and II GTPase Activity and Endocytosis

Journal of medicinal chemistry, 2010-05, Vol.53 (10), p.4094-4102

2010

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Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice

Journal of medicinal chemistry, 2010-12, Vol.53 (23), p.8400-8408

2010

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Norcantharidin Analogues: Synthesis, Anticancer Activity and Protein Phosphatase 1 and 2A Inhibition

ChemMedChem, 2008-12, Vol.3 (12), p.1878-1892

2008

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Comparative α-Helicity of Cyclic Pentapeptides in Water

Angewandte Chemie (International ed.), 2014-07, Vol.53 (27), p.6965-6969

2014

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A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells

Cancer research (Chicago, Ill.), 2013-08, Vol.73 (16), p.5169-5182

2013

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28 GHz Taylor feed network for sidelobe level reduction in 5G phased array antennas

Microwave and optical technology letters, 2019-01, Vol.61 (1), p.37-43

2019

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Helical structure in cyclic peptides: effect of N -methyl amides versus esters

Chemical communications (Cambridge, England), 2022-11, Vol.58 (89), p.12475-12478

2022

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Cascaded Fresnel Lens Antenna for Scan Loss Mitigation in Millimeter-Wave Access Points

IEEE transactions on antennas and propagation, 2020-10, Vol.68 (10), p.6879-6892

2020

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Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles

Journal of medicinal chemistry, 2022-09, Vol.65 (17), p.11759-11775

2022

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Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells

Journal of cell communication and signaling, 2023-12, Vol.17 (4), p.1293-1307

2023

Volltextzugriff (PDF)

A Novel Long‐Range n to π Interaction Secures the Smallest known α‐Helix in Water

Angewandte Chemie International Edition, 2019-12, Vol.58 (52), p.18873-18877

International ed. in English, 2019

Volltextzugriff (PDF)

Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm

Developmental cell, 2024-03, Vol.59 (6), p.705-722.e8

2024

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Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability

Organic & biomolecular chemistry, 2018, Vol.16 (3), p.367-371

2018

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Structure-Activity Relationships of Wollamide Cyclic Hexapeptides with Activity against Drug-Resistant and Intracellular Mycobacterium tuberculosis

Antimicrobial agents and chemotherapy, 2019-03, Vol.63 (3)

2019

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Constraining Cyclic Peptides To Mimic Protein Structure Motifs

Connecting Hydrophobic Surfaces in Cyclic Peptides Increases Membrane Permeability

Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable

Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities

Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages

Inhibition of Dynamin Mediated Endocytosis by the DynolesSynthesis and Functional Activity of a Family of Indoles

Truncated and helix-constrained peptides with high affinity and specificity for the cFos coiled-coil of AP-1

Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis

Crystal Structures of Protein-Bound Cyclic Peptides

Iminochromene Inhibitors of Dynamins I and II GTPase Activity and Endocytosis

Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice

Norcantharidin Analogues: Synthesis, Anticancer Activity and Protein Phosphatase 1 and 2A Inhibition

Comparative α-Helicity of Cyclic Pentapeptides in Water

A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells

28 GHz Taylor feed network for sidelobe level reduction in 5G phased array antennas

Helical structure in cyclic peptides: effect of N -methyl amides versus esters

Cascaded Fresnel Lens Antenna for Scan Loss Mitigation in Millimeter-Wave Access Points

Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles

Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells

A Novel Long‐Range n to π Interaction Secures the Smallest known α‐Helix in Water

Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm

Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability

Structure-Activity Relationships of Wollamide Cyclic Hexapeptides with Activity against Drug-Resistant and Intracellular Mycobacterium tuberculosis

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