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Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)

Antimicrobial Agents and Chemotherapy, 2009-12, Vol.53 (12), p.5265-5274

2009

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Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin

Antimicrobial Agents and Chemotherapy, 2009-12, Vol.53 (12), p.5275-5278

2009

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Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7‑(Benzimidazol-1-yl)-2,4-diaminoquinazolines

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.651-668

2014

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Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics

Nature communications, 2020-05, Vol.11 (1), p.2330-2330, Article 2330

2020

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Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations

Antimicrobial Agents and Chemotherapy, 2010-12, Vol.54 (12), p.5337-5343

2010

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Structures of the N-Terminal Modules Imply Large Domain Motions during Catalysis by Methionine Synthase

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (11), p.3729-3736

2004

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Identification of Bacteria-Selective Threonyl-tRNA Synthetase Substrate Inhibitors by Structure-Based Design

Journal of medicinal chemistry, 2013-02, Vol.56 (4), p.1748-1760

2013

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Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy

NPJ breast cancer, 2022-11, Vol.8 (1), p.126-126, Article 126

2022

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Coexistence patterns of two larval helminth parasites associated with their intermediate host, the mole crab Emerita analoga Stimpson, 1857 (Decapoda: Anomura: Hippidae)

Journal of crustacean biology, 2018-05, Vol.38 (3), p.278-284

2018

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Elevated Linezolid Resistance in Clinical cfr-Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3

Antimicrobial Agents and Chemotherapy, 2010-12, Vol.54 (12), p.5352-5355

2010

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Author Correction: Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy

NPJ breast cancer, 2022-12, Vol.8 (1), p.133-133, Article 133

2022

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Crystal Structure of the Quorum-Sensing Protein LuxS Reveals a Catalytic Metal Site

Proceedings of the National Academy of Sciences - PNAS, 2001-09, Vol.98 (20), p.11169-11174

2001

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Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:l-Alanine Ligase (MurC) from Haemophilus influenzae

Journal of Bacteriology, 2003-07, Vol.185 (14), p.4152-4162

2003

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Comparison of the Essential Cellular Functions of the Two murA Genes of Bacillus anthracis

Antimicrobial Agents and Chemotherapy, 2008-06, Vol.52 (6), p.2009-2013

2008

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Evaluation of the metS and murB Loci for Antibiotic Discovery Using Targeted Antisense RNA Expression Analysis in Bacillus anthracis

Antimicrobial Agents and Chemotherapy, 2007-05, Vol.51 (5), p.1708-1718

2007

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Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5171-5176

2011

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Conformational Flexibility in Crystal Structures of Human 11β-Hydroxysteroid Dehydrogenase Type I Provide Insights into Glucocorticoid Interconversion and Enzyme Regulation

The Journal of biological chemistry, 2005-02, Vol.280 (6), p.4639-4648

2005

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A fully integrated protein crystallization platform for small-molecule drug discovery

Journal of structural biology, 2003-04, Vol.142 (1), p.207-217

2003

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Identification of novel inhibitors of methionyl-tRNA synthetase (MetRS) by virtual screening

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.3932-3937

2008

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Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation

The Journal of biological chemistry, 2005-02, Vol.280 (6), p.4639

2005

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Conformational Flexibility in Crystal Structures of Human 11Î²-Hydroxysteroid Dehydrogenase Type I Provide Insights into Glucocorticoid Interconversion and Enzyme Regulation

The Journal of biological chemistry, 2005-02, Vol.280 (6), p.4639

2005

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The structure of LuxS, a bacterial protein implicated in intercellular signaling

Hilgers, Mark Theodore

2001

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High salt reduces the activation of IL-4- and IL-13-stimulated macrophages

The Journal of clinical investigation, 2015-11, Vol.125 (11), p.4223-4238

2015

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The Combined Loss of Triose Phosphate and Xylulose 5-Phosphate/Phosphate Translocators Leads to Severe Growth Retardation and Impaired Photosynthesis in Arabidopsis thaliana tpt/xpt Double Mutants

Frontiers in plant science, 2018-10, Vol.9, p.1331-1331

2018

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Effects of Smoking Cessation on Presynaptic Dopamine Function of Addicted Male Smokers

Biological psychiatry (1969), 2016-08, Vol.80 (3), p.198-206

2016

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Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)

Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin

Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7‑(Benzimidazol-1-yl)-2,4-diaminoquinazolines

Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics

Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations

Structures of the N-Terminal Modules Imply Large Domain Motions during Catalysis by Methionine Synthase

Identification of Bacteria-Selective Threonyl-tRNA Synthetase Substrate Inhibitors by Structure-Based Design

Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy

Coexistence patterns of two larval helminth parasites associated with their intermediate host, the mole crab Emerita analoga Stimpson, 1857 (Decapoda: Anomura: Hippidae)

Elevated Linezolid Resistance in Clinical cfr-Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3

Author Correction: Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacy

Crystal Structure of the Quorum-Sensing Protein LuxS Reveals a Catalytic Metal Site

Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:l-Alanine Ligase (MurC) from Haemophilus influenzae

Comparison of the Essential Cellular Functions of the Two murA Genes of Bacillus anthracis

Evaluation of the metS and murB Loci for Antibiotic Discovery Using Targeted Antisense RNA Expression Analysis in Bacillus anthracis

Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines

Conformational Flexibility in Crystal Structures of Human 11β-Hydroxysteroid Dehydrogenase Type I Provide Insights into Glucocorticoid Interconversion and Enzyme Regulation

A fully integrated protein crystallization platform for small-molecule drug discovery

Identification of novel inhibitors of methionyl-tRNA synthetase (MetRS) by virtual screening

Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation

Conformational Flexibility in Crystal Structures of Human 11Î²-Hydroxysteroid Dehydrogenase Type I Provide Insights into Glucocorticoid Interconversion and Enzyme Regulation

The structure of LuxS, a bacterial protein implicated in intercellular signaling

High salt reduces the activation of IL-4- and IL-13-stimulated macrophages

The Combined Loss of Triose Phosphate and Xylulose 5-Phosphate/Phosphate Translocators Leads to Severe Growth Retardation and Impaired Photosynthesis in Arabidopsis thaliana tpt/xpt Double Mutants

Effects of Smoking Cessation on Presynaptic Dopamine Function of Addicted Male Smokers

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