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Elevated cerebrospinal fluid quinolinic acid levels are associated with region-specific cerebral volume loss in HIV infection

Brain (London, England : 1878), 2001-05, Vol.124 (5), p.1033-1042

2001

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Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages

Journal of neuroimmunology, 2001-07, Vol.117 (1), p.97-107

2001

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A mechanism for increased quinolinic acid formation following acute systemic immune stimulation

The Journal of biological chemistry, 1993-07, Vol.268 (21), p.15496-15503

1993

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Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse

Neuroscience, 1992-11, Vol.51 (1), p.25-39

1992

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QUINOLINIC ACID AND KYNURENINE PATHWAY METABOLISM IN INFLAMMATORY AND NON-INFLAMMATORY NEUROLOGICAL DISEASE

Brain (London, England : 1878), 1992-10, Vol.115 (5), p.1249-1273

1992

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A mechanism of quinolinic acid formation by brain in inflammatory neurological disease : attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate

Brain (London, England : 1878), 1993-12, Vol.116 (6), p.1425-1450

1993

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Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid

Biochemical journal, 1992-05, Vol.283 (3), p.633-635

1992

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Prediction of Clinical Drug Efficacy by Classification of Drug-Induced Genomic Expression Profiles in vitro

Proceedings of the National Academy of Sciences - PNAS, 2003-08, Vol.100 (16), p.9608-9613

2003

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Effects of methylprednisolone and 4-chloro-3-hydroxyanthranilic acid in experimental spinal cord injury in the guinea pig appear to be mediated by different and potentially complementary mechanisms

Spinal cord, 2014-09, Vol.52 (9), p.662-666

2014

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Quinolinic acid in cerebrospinal fluid and serum in HIV-1 Infection: Relationship to clinical and neurological status

Annals of neurology, 1991-02, Vol.29 (2), p.202-209

1991

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Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains

The Journal of clinical investigation, 1993-06, Vol.91 (6), p.2769-2775

1993

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Mechanism of Delayed Increases in Kynurenine Pathway Metabolism in Damaged Brain Regions Following Transient Cerebral Ischemia

Journal of neurochemistry, 1993-01, Vol.60 (1), p.180-192

1993

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Quantification of Local De Novo Synthesis Versus Blood Contributions to Quinolinic Acid Concentrations in Brain and Systemic Tissues

Journal of neurochemistry, 1997-01, Vol.68 (1), p.280-288

1997

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Prospective study of neurological responses to treatment with macrophage-targeted glucocerebrosidase in patients with type 3 Gaucher's disease

Annals of neurology, 1997-10, Vol.42 (4), p.613-621

1997

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Quinolinic acid accumulation and functional deficits following experimental spinal cord injury

Brain (London, England : 1878), 1995-06, Vol.118 (3), p.735-752

1995

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4-chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-γ-stimulated monocytes (THP-1 cells)

Biochemical journal, 1993-04, Vol.291 (1), p.11-14

1993

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Scleroderma, Fasciitis, and Eosinophilia Associated with the Ingestion of Tryptophan

The New England journal of medicine, 1990-03, Vol.322 (13), p.874-881

1990

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Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the l‐kynurenine and quinolinic acid pools in brain

Journal of neurochemistry, 2002-07, Vol.82 (2), p.258-268

2002

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Species Heterogeneity Between Gerbils and Rats: Quinolinate Production by Microglia and Astrocytes and Accumulations in Response to Ischemic Brain Injury and Systemic Immune Activation

Journal of neurochemistry, 1997-10, Vol.69 (4), p.1519-1529

1997

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Quinolinic Acid In Vivo Synthesis Rates, Extracellular Concentrations, and Intercompartmental Distributions in Normal and Immune‐Activated Brain as Determined by Multiple‐Isotope Microdialysis

Journal of neurochemistry, 1998-01, Vol.70 (1), p.281-291

1998

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Quinolinic acid is increased in CSF and associated with mortality after traumatic brain injury in humans

Journal of cerebral blood flow and metabolism, 1998-06, Vol.18 (6), p.610-615

1998

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Quinolinic acid in the cerebrospinal fluid of children after traumatic brain injury

Critical care medicine, 1999-03, Vol.27 (3), p.493-497

1999

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Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency

American journal of physiology. Renal physiology, 2000-09, Vol.279 (3), p.F565-F572

2000

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Metabolism and neuropathologic significance of quinolinic acid and kynurenic acid

Biochemical Society transactions, 1993-02, Vol.21 (1), p.83-89

Heyes, M P

1993

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Kynurenine Pathway Enzymes in Brain: Responses to Ischemic Brain Injury Versus Systemic Immune Activation

Journal of neurochemistry, 1993-12, Vol.61 (6), p.2061-2070

1993

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Elevated cerebrospinal fluid quinolinic acid levels are associated with region-specific cerebral volume loss in HIV infection

Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages

A mechanism for increased quinolinic acid formation following acute systemic immune stimulation

Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse

QUINOLINIC ACID AND KYNURENINE PATHWAY METABOLISM IN INFLAMMATORY AND NON-INFLAMMATORY NEUROLOGICAL DISEASE

A mechanism of quinolinic acid formation by brain in inflammatory neurological disease : attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate

Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid

Prediction of Clinical Drug Efficacy by Classification of Drug-Induced Genomic Expression Profiles in vitro

Effects of methylprednisolone and 4-chloro-3-hydroxyanthranilic acid in experimental spinal cord injury in the guinea pig appear to be mediated by different and potentially complementary mechanisms

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 Infection: Relationship to clinical and neurological status

Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains

Mechanism of Delayed Increases in Kynurenine Pathway Metabolism in Damaged Brain Regions Following Transient Cerebral Ischemia

Quantification of Local De Novo Synthesis Versus Blood Contributions to Quinolinic Acid Concentrations in Brain and Systemic Tissues

Prospective study of neurological responses to treatment with macrophage-targeted glucocerebrosidase in patients with type 3 Gaucher's disease

Quinolinic acid accumulation and functional deficits following experimental spinal cord injury

4-chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-γ-stimulated monocytes (THP-1 cells)

Scleroderma, Fasciitis, and Eosinophilia Associated with the Ingestion of Tryptophan

Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the l‐kynurenine and quinolinic acid pools in brain

Species Heterogeneity Between Gerbils and Rats: Quinolinate Production by Microglia and Astrocytes and Accumulations in Response to Ischemic Brain Injury and Systemic Immune Activation

Quinolinic Acid In Vivo Synthesis Rates, Extracellular Concentrations, and Intercompartmental Distributions in Normal and Immune‐Activated Brain as Determined by Multiple‐Isotope Microdialysis

Quinolinic acid is increased in CSF and associated with mortality after traumatic brain injury in humans

Quinolinic acid in the cerebrospinal fluid of children after traumatic brain injury

Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency

Metabolism and neuropathologic significance of quinolinic acid and kynurenic acid

Kynurenine Pathway Enzymes in Brain: Responses to Ischemic Brain Injury Versus Systemic Immune Activation

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