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Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (43), p.17644-17648

2011

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Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

Cell, 2011-04, Vol.145 (2), p.212-223

2011

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Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (23), p.6010-6015

2017

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Periplasmic binding proteins: a versatile superfamily for protein engineering

Current opinion in structural biology, 2004-08, Vol.14 (4), p.495-504

2004

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Multifactorial Determinants of Protein Expression in Prokaryotic Open Reading Frames

Journal of molecular biology, 2010-10, Vol.402 (5), p.905-918

2010

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Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching

Communications chemistry, 2023-08, Vol.6 (1), p.168-168, Article 168

2023

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Programmable ligand detection system in plants through a synthetic signal transduction pathway

PloS one, 2011-01, Vol.6 (1), p.e16292

2011

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Structural Reorganization and Preorganization in Enzyme Active Sites: Comparisons of Experimental and Theoretically Ideal Active Site Geometries in the Multistep Serine Esterase Reaction Cycle

Journal of the American Chemical Society, 2008-11, Vol.130 (46), p.15361-15373

2008

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Thermally controlled intein splicing of engineered DNA polymerases provides a robust and generalizable solution for accurate and sensitive molecular diagnostics

Nucleic acids research, 2023-06, Vol.51 (11), p.5883

2023

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Discovery of Thermostable, Fluorescently Responsive Glucose Biosensors by Structure-Assisted Function Extrapolation

Biochemistry (Easton), 2022-02, Vol.61 (4), p.276-293

2022

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Construction of a fluorescent biosensor family

Protein science, 2002-11, Vol.11 (11), p.2655-2675

2002

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Conversion of a Maltose Receptor into a Zinc Biosensor by Computational Design

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (9), p.4955-4960

2001

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Describing Complex Structure-Function Relationships in Biomolecules at Equilibrium

Journal of molecular biology, 2020-03, Vol.432 (7), p.1926-1951

2020

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Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold

The Journal of biological chemistry, 2009-11, Vol.284 (48), p.33217-33223

2009

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Harnessing Environmental Ca2+ for Extracellular Protein Thermostabilization

Biochemistry (Easton), 2020-10, Vol.59 (39), p.3725-3740

2020

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Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (11), p.4908-4913

2010

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Harnessing Environmental Ca 2+ for Extracellular Protein Thermostabilization

Biochemistry (Easton), 2020-10, Vol.59 (39), p.3725-3740

2020

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Thermodynamic Analysis of Ligand-Induced Changes in Protein Thermal Unfolding Applied to High-Throughput Determination of Ligand Affinities with Extrinsic Fluorescent Dyes

Biochemistry (Easton), 2010-12, Vol.49 (51), p.10831-10841

2010

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Identification of cognate ligands for the Escherichia coli phnD protein product and engineering of a reagentless fluorescent biosensor for phosphonates

Protein science, 2006-07, Vol.15 (7), p.1745-1751

2006

Volltextzugriff (PDF)

Computational Design of Receptors for an Organophosphate Surrogate of the Nerve Agent Soman

Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (21), p.7907-7912

2004

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Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase

Journal of medicinal chemistry, 2022-10, Vol.65 (20), p.13753-13770

2022

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Visualization of synaptic inhibition with an optogenetic sensor developed by cell-free protein engineering automation

The Journal of neuroscience, 2013-10, Vol.33 (41), p.16297-16309

2013

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Quantitation of protein–protein interactions by thermal stability shift analysis

Protein science, 2011-08, Vol.20 (8), p.1439-1450

2011

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Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides

The Journal of biological chemistry, 2012-08, Vol.287 (34), p.28215-28226

2012

Volltextzugriff (PDF)

Structure‐based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose‐binding protein

Protein science, 2007-10, Vol.16 (10), p.2240-2250

2007

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Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

Periplasmic binding proteins: a versatile superfamily for protein engineering

Multifactorial Determinants of Protein Expression in Prokaryotic Open Reading Frames

Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching

Programmable ligand detection system in plants through a synthetic signal transduction pathway

Structural Reorganization and Preorganization in Enzyme Active Sites: Comparisons of Experimental and Theoretically Ideal Active Site Geometries in the Multistep Serine Esterase Reaction Cycle

Thermally controlled intein splicing of engineered DNA polymerases provides a robust and generalizable solution for accurate and sensitive molecular diagnostics

Discovery of Thermostable, Fluorescently Responsive Glucose Biosensors by Structure-Assisted Function Extrapolation

Construction of a fluorescent biosensor family

Conversion of a Maltose Receptor into a Zinc Biosensor by Computational Design

Describing Complex Structure-Function Relationships in Biomolecules at Equilibrium

Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold

Harnessing Environmental Ca2+ for Extracellular Protein Thermostabilization

Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity

Harnessing Environmental Ca 2+ for Extracellular Protein Thermostabilization

Thermodynamic Analysis of Ligand-Induced Changes in Protein Thermal Unfolding Applied to High-Throughput Determination of Ligand Affinities with Extrinsic Fluorescent Dyes

Identification of cognate ligands for the Escherichia coli phnD protein product and engineering of a reagentless fluorescent biosensor for phosphonates

Computational Design of Receptors for an Organophosphate Surrogate of the Nerve Agent Soman

Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase

Visualization of synaptic inhibition with an optogenetic sensor developed by cell-free protein engineering automation

Quantitation of protein–protein interactions by thermal stability shift analysis

Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides

Structure‐based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose‐binding protein

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