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Mechanism of antagonist ligand binding to REV-ERBα

Scientific reports, 2024-04, Vol.14 (1), p.8401-8401, Article 8401

2024

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Recent Advances in the Medicinal Chemistry of Liver X Receptors

Journal of medicinal chemistry, 2018-12, Vol.61 (24), p.10935-10956

2018

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Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

Nature communications, 2022-11, Vol.13 (1), p.7131-7131, Article 7131

2022

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Pharmacophore modeling for biological targets with high flexibility: LXRβ case study

Medicine in drug discovery, 2022-09, Vol.15, p.100135, Article 100135

2022

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Design, Synthesis and Antitumor Activity of Novel Dispiro[oxindole-cyclohexanone]- pyrrolidines

Current pharmaceutical design, 2022, Vol.28 (3), p.198-207

2022

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Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor

Nature communications, 2023-12, Vol.14 (1), p.8064-8064, Article 8064

2023

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Recent Advances in the Medicinal Chemistry of Liver X Receptors: Miniperspective

Journal of medicinal chemistry, 2018-12, Vol.61 (24), p.10935-10956

2018

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Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening

Biomedicines, 2022-02, Vol.10 (2), p.365

2022

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A sulfoximine-based inhibitor of human asparagine synthetase kills l-asparaginase-resistant leukemia cells

Bioorganic & medicinal chemistry, 2012-10, Vol.20 (19), p.5915-5927

2012

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Catalyst-and organic solvent-free synthesis, structural, and theoretical studies of 1-arylidenamino-2,4-disubstituted-2-imidazoline-5-ones

Results in Chemistry, 2020-01, Vol.2, p.100042, Article 100042

2020

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Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor

Journal of medicinal chemistry, 2021-12, Vol.64 (24), p.17545-17571

2021

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Catalyst- and organic solvent-free synthesis of thioacids in water

Tetrahedron letters, 2019-07, Vol.60 (30), p.2018-2021

2019

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Assigning pathogenicity for TAB2 variants using a novel scalable functional assay and expanding TAB2 disease spectrum

Human molecular genetics, 2023-03, Vol.32 (6), p.959-970

2023

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Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice

The Journal of biological chemistry, 2022-02, Vol.298 (2), p.101554-101554, Article 101554

2022

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The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids

Cell chemical biology, 2020-10, Vol.27 (10), p.1272-1284.e4

2020

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Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

ACS chemical biology, 2023-04, Vol.18 (4), p.756-771

2023

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The larvicidal activity of natural inspired piperine-based dienehydrazides against Culex pipiens

Bioorganic chemistry, 2020-01, Vol.94, p.103464, Article 103464

2020

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Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold

Bioorganic & medicinal chemistry letters, 2019-02, Vol.29 (3), p.449-453

2019

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Synthesis and structure activity relationship of the first class of LXR inverse agonists

Bioorganic chemistry, 2022-02, Vol.119, p.105540-105540, Article 105540

2022

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Identification of 4-isopropyl-thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation

RSC advances, 2018-01, Vol.8 (52), p.29967-29975

2018

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Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRβ/γ selective agonist to ERRα/β/γ pan agonists

Bioorganic chemistry, 2020-09, Vol.102, p.104079-104079, Article 104079

2020

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Synthesis and DFT studies of an antitumor active spiro-oxindole

New journal of chemistry, 2015-01, Vol.39 (10), p.8017-8027

2015

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Potent antiplasmodial alkaloids from the rhizobacterium Pantoea agglomerans as hemozoin modulators

Bioorganic chemistry, 2021-10, Vol.115, p.105215, Article 105215

2021

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Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold

Bioorganic chemistry, 2020-07, Vol.100, p.103878, Article 103878

2020

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Mechanism of antagonist ligand binding to REV-ERBα

Recent Advances in the Medicinal Chemistry of Liver X Receptors

Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

Pharmacophore modeling for biological targets with high flexibility: LXRβ case study

Design, Synthesis and Antitumor Activity of Novel Dispiro[oxindole-cyclohexanone]- pyrrolidines

Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor

International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023

Recent Advances in the Medicinal Chemistry of Liver X Receptors: Miniperspective

Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening

A sulfoximine-based inhibitor of human asparagine synthetase kills l-asparaginase-resistant leukemia cells

Catalyst-and organic solvent-free synthesis, structural, and theoretical studies of 1-arylidenamino-2,4-disubstituted-2-imidazoline-5-ones

Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor

Catalyst- and organic solvent-free synthesis of thioacids in water

Assigning pathogenicity for TAB2 variants using a novel scalable functional assay and expanding TAB2 disease spectrum

Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice

The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids

Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

The larvicidal activity of natural inspired piperine-based dienehydrazides against Culex pipiens

Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold

Synthesis and structure activity relationship of the first class of LXR inverse agonists

Identification of 4-isopropyl-thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation

Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRβ/γ selective agonist to ERRα/β/γ pan agonists

Synthesis and DFT studies of an antitumor active spiro-oxindole

Potent antiplasmodial alkaloids from the rhizobacterium Pantoea agglomerans as hemozoin modulators

Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold

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