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1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5 H-pyrimido[4,5- d]azepines as TRPV1 antagonists with improved properties

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (23), p.7142-7146

2010

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1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (23), p.7142-7146

2010

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1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry letters, 2014-03, Vol.24 (5), p.1280-1284

2014

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2‐Pyridinylpiperazine Carboxamide Class and Related TRPV1 Antagonists

Vanilloid Receptor TRPV1 in Drug Discovery, 2010, p.311-324

2010

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Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene

Journal of organic chemistry, 2000-12, Vol.65 (24), p.8379-8380

2000

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ChemInform Abstract: Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene

ChemInform, 2001-04, Vol.32 (16), p.no-no

2001

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ChemInform Abstract: Synthesis of (-)-Dysiherbaine

ChemInform, 2000-06, Vol.31 (25), p.no-no

2000

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ChemInform Abstract: Synthesis of the Hydroazulene Ring System of Guanacastepene

ChemInform, 2001-06, Vol.32 (25), p.no-no

2001

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Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures 1

Journal of the American Chemical Society, 2001-10, Vol.123 (43), p.10475-10488

2001

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Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures1

Journal of the American Chemical Society, 2001-10, Vol.123 (43), p.10475-10488

2001

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Discovery and synthesis of 6,7,8,9-tetrahydro-5 H-pyrimido-[4,5- d]azepines as novel TRPV1 antagonists

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (23), p.7137-7141

2010

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Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (23), p.7137-7141

2010

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Discovery of a novel series of selective HCN1 blockers

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5197-5201

2011

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Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis

ACS medicinal chemistry letters, 2018-03, Vol.9 (3), p.210-214

2018

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Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections

Journal of medicinal chemistry, 2022-08, Vol.65 (16), p.11388-11403

2022

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Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis

Antimicrobial agents and chemotherapy, 2021-06, Vol.65 (7), p.e0025321-e0025321

2021

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Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing

JAMA dermatology (Chicago, Ill.), 2023-05, Vol.159 (5), p.545

2023

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EDG-002, A NOVEL TARGETED SARCOMERE REGULATOR PRESERVES INTRINSIC MYOSIN-MOTOR FUNCTION, BLUNTS HYPERCONTRACTILITY AND ELIMINATES LVOT OBSTRUCTION IN CATS WITH HYPERTROPHIC CARDIOMYOPATHY: IN VITRO AND IN VIVO EVIDENCE

Journal of the American College of Cardiology, 2023-03, Vol.81 (8), p.349-349

2023

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Evidence for dispensability of protein kinase R in host control of tuberculosis

European journal of immunology, 2018-04, Vol.48 (4), p.612-620

2018

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Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization

International journal for parasitology -- drugs and drug resistance, 2022-08, Vol.19, p.89-97

2022

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Formal Synthesis of (±)-Guanacastepene A

Journal of organic chemistry, 2003-02, Vol.68 (3), p.1030-1042

2003

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Formal Synthesis of (.+-.)-Guanacastepene A

ChemInform, 2003-06, Vol.34 (23), p.no-no

2003

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Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure–mutagenicity relationships for arylamine metabolites

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7357-7362

2012

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Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structureamutagenicity relationships for arylamine metabolites

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7357-7362

2012

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Identification and characterization of a novel class of interleukin-1 post-translational processing inhibitors

The Journal of pharmacology and experimental therapeutics, 2001-10, Vol.299 (1), p.187

2001

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1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5 H-pyrimido[4,5- d]azepines as TRPV1 antagonists with improved properties

1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

2‐Pyridinylpiperazine Carboxamide Class and Related TRPV1 Antagonists

Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene

ChemInform Abstract: Alcohol Inversion Using Cesium Carboxylates and DMAP in Toluene

ChemInform Abstract: Synthesis of (-)-Dysiherbaine

ChemInform Abstract: Synthesis of the Hydroazulene Ring System of Guanacastepene

Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures 1

Complexation-Induced Unfolding of Heterocyclic Ureas. Simple Foldamers Equilibrate with Multiply Hydrogen-Bonded Sheetlike Structures1

Discovery and synthesis of 6,7,8,9-tetrahydro-5 H-pyrimido-[4,5- d]azepines as novel TRPV1 antagonists

Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists

Discovery of a novel series of selective HCN1 blockers

Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis

Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections

Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis

Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing

EDG-002, A NOVEL TARGETED SARCOMERE REGULATOR PRESERVES INTRINSIC MYOSIN-MOTOR FUNCTION, BLUNTS HYPERCONTRACTILITY AND ELIMINATES LVOT OBSTRUCTION IN CATS WITH HYPERTROPHIC CARDIOMYOPATHY: IN VITRO AND IN VIVO EVIDENCE

Evidence for dispensability of protein kinase R in host control of tuberculosis

Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization

Formal Synthesis of (±)-Guanacastepene A

Formal Synthesis of (.+-.)-Guanacastepene A

Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure–mutagenicity relationships for arylamine metabolites

Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structureamutagenicity relationships for arylamine metabolites

Identification and characterization of a novel class of interleukin-1 post-translational processing inhibitors

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