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The Ubiquitous Aldehyde Reductase (AKR1A1) Oxidizes Proximate Carcinogen trans-Dihydrodiols to o-Quinones: Potential Role in Polycyclic Aromatic Hydrocarbon Activation

Biochemistry (Easton), 2001-09, Vol.40 (36), p.10901-10910

2001

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Clinical and serological associations with anti‐RNA polymerase antibodies in systemic sclerosis

Clinical and experimental immunology, 1999-08, Vol.117 (2), p.395-402

1999

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Metabolism of Benzo[a]pyrene in Human Bronchoalveolar H358 Cells Using Liquid Chromatography–Mass Spectrometry

Chemical research in toxicology, 2007-09, Vol.20 (9), p.1331-1341

2007

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New Synthetic Approaches to Polycyclic Aromatic Hydrocarbons and Their Carcinogenic Oxidized Metabolites: Derivatives of Benzo[s]picene, Benzo[r st]pentaphene, and Dibenzo[b,d ef]chrysene

Journal of organic chemistry, 2000-06, Vol.65 (13), p.3952-3960

2000

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Marine Humic and Fulvic Acids: Their Effects on Remote Sensing of Ocean Chlorophyll

Limnology and oceanography, 1989-01, Vol.34 (1), p.68-81

1989

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Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells

The Journal of biological chemistry, 2002-07, Vol.277 (27), p.24799-24808

2002

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The modulation of the expression of IL-6 and its receptor in human osteoblasts In vitro

Endocrinology (Philadelphia), 1991-09, Vol.129 (3), p.1513-1520

1991

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A blinded, placebo-controlled study of the efficacy of borage seed oil and fish oil in the management of canine atopy

Veterinary record, 1999-04, Vol.144 (15), p.405-407

Harvey, R. G.

1999

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Influence of hydrophobic mismatch on the catalytic activity of Escherichia coli GlpG rhomboid protease

Protein science, 2015-04, Vol.24 (4), p.464-473

2015

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Reactivity of benzo[a]pyrene-7,8-dione with DNA. Evidence for the formation of deoxyguanosine adducts

Carcinogenesis (New York), 1993-03, Vol.14 (3), p.475-482

1993

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Tumorigenicity in newborn mice of fjord region and other sterically hindered diol epoxides of benzo[g]chrysene, dibenzo[a, l]pyrene (dibenzo[def, p]chrysene), 4H-cyclopenta[def]chrysene and fluoranthene

Carcinogenesis (New York), 1995-11, Vol.16 (11), p.2813-2817

1995

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First Examples of Stable Arenium Ions from Large Methylene-Bridged Polycyclic Aromatic Hydrocarbons (PAHs). Directive Effects and Charge Delocalization Mode

Journal of organic chemistry, 2001-06, Vol.66 (11), p.3977-3983

2001

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Formation of 8-Oxo-7,8-dihydro-2‘-deoxyguanosine (8-Oxo-dGuo) by PAH o-Quinones: Involvement of Reactive Oxygen Species and Copper(II)/Copper(I) Redox Cycling

Chemical research in toxicology, 2005-06, Vol.18 (6), p.1026-1037

2005

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Synthesis of Benzo[s]picene and its Putative Carcinogenic trans-3,4-Dihydrodiol and Fjord Region anti-Diol Epoxide Metabolites

Journal of organic chemistry, 1998-09, Vol.63 (18), p.6405-6408

1998

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Spectroscopic identification of ortho-quinones as the products of polycyclic aromatic trans-dihydrodiol oxidation catalyzed by dihydrodiol dehydrogenase. A potential route of proximate carcinogen metabolism

The Journal of biological chemistry, 1988-02, Vol.263 (4), p.1814-1820

1988

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Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: Intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair

Biochemistry (Easton), 1993-11, Vol.32 (46), p.12488-12497

1993

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Regio- and stereospecificity of homogeneous 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase for trans-dihydrodiol metabolites of polycyclic aromatic hydrocarbons

The Journal of biological chemistry, 1986-05, Vol.261 (14), p.6184-6191

1986

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Spectroscopic characteristics and site I/site II classification of cis and trans benzo[a]pyrene diolepoxide enantiomer-guanosine adducts in oligonucleotides and polynucleotides

Carcinogenesis (New York), 1991-11, Vol.12 (11), p.2099-2108

1991

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Mutagenicity of benzo[ a]pyrene–deoxyadenosine adducts in a sequence context derived from the p53 gene

Mutation research, 2000-02, Vol.465 (1), p.39-44

2000

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Photoreduction of manganese oxides in seawater and its geochemical and biological implications

Nature (London), 1983, Vol.301 (5897), p.234-236

1983

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Expression and Characterization of Four Recombinant Human Dihydrodiol Dehydrogenase Isoforms: Oxidation of trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene to the Activated o-Quinone Metabolite Benzo[a]pyrene-7,8-dione

Biochemistry (Easton), 1998-05, Vol.37 (19), p.6781-6790

1998

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Anti‐RNA polymerase antibodies in systemic sclerosis (SSc): association with anti‐topoisomerase I antibodies and identification of autoreactive subunits of RNA polymerase II

Clinical and experimental immunology, 1996-09, Vol.105 (3), p.468-474

1996

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Metabolic activation of benzo[g]chrysene in the human mammary carcinoma cell line MCF-7

Cancer research (Chicago, Ill.), 1997-02, Vol.57 (3), p.415-419

1997

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Generation of Reactive Oxygen Species during the Enzymatic Oxidation of Polycyclic Aromatic Hydrocarbon trans-Dihydrodiols Catalyzed by Dihydrodiol Dehydrogenase

Chemical research in toxicology, 1996-01, Vol.9 (1), p.84-92

1996

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Cytotoxicity of polycyclic aromatic hydrocarbon o-quinones in rat and human hepatoma cells

Chemical research in toxicology, 1993-05, Vol.6 (3), p.252-260

1993

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The Ubiquitous Aldehyde Reductase (AKR1A1) Oxidizes Proximate Carcinogen trans-Dihydrodiols to o-Quinones: Potential Role in Polycyclic Aromatic Hydrocarbon Activation

Clinical and serological associations with anti‐RNA polymerase antibodies in systemic sclerosis

Metabolism of Benzo[a]pyrene in Human Bronchoalveolar H358 Cells Using Liquid Chromatography–Mass Spectrometry

New Synthetic Approaches to Polycyclic Aromatic Hydrocarbons and Their Carcinogenic Oxidized Metabolites: Derivatives of Benzo[s]picene, Benzo[r st]pentaphene, and Dibenzo[b,d ef]chrysene

Marine Humic and Fulvic Acids: Their Effects on Remote Sensing of Ocean Chlorophyll

Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells

The modulation of the expression of IL-6 and its receptor in human osteoblasts In vitro

A blinded, placebo-controlled study of the efficacy of borage seed oil and fish oil in the management of canine atopy

Influence of hydrophobic mismatch on the catalytic activity of Escherichia coli GlpG rhomboid protease

Reactivity of benzo[a]pyrene-7,8-dione with DNA. Evidence for the formation of deoxyguanosine adducts

Tumorigenicity in newborn mice of fjord region and other sterically hindered diol epoxides of benzo[g]chrysene, dibenzo[a, l]pyrene (dibenzo[def, p]chrysene), 4H-cyclopenta[def]chrysene and fluoranthene

First Examples of Stable Arenium Ions from Large Methylene-Bridged Polycyclic Aromatic Hydrocarbons (PAHs). Directive Effects and Charge Delocalization Mode

Formation of 8-Oxo-7,8-dihydro-2‘-deoxyguanosine (8-Oxo-dGuo) by PAH o-Quinones: Involvement of Reactive Oxygen Species and Copper(II)/Copper(I) Redox Cycling

Synthesis of Benzo[s]picene and its Putative Carcinogenic trans-3,4-Dihydrodiol and Fjord Region anti-Diol Epoxide Metabolites

Spectroscopic identification of ortho-quinones as the products of polycyclic aromatic trans-dihydrodiol oxidation catalyzed by dihydrodiol dehydrogenase. A potential route of proximate carcinogen metabolism

Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: Intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair

Regio- and stereospecificity of homogeneous 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase for trans-dihydrodiol metabolites of polycyclic aromatic hydrocarbons

Spectroscopic characteristics and site I/site II classification of cis and trans benzo[a]pyrene diolepoxide enantiomer-guanosine adducts in oligonucleotides and polynucleotides

Mutagenicity of benzo[ a]pyrene–deoxyadenosine adducts in a sequence context derived from the p53 gene

Photoreduction of manganese oxides in seawater and its geochemical and biological implications

Expression and Characterization of Four Recombinant Human Dihydrodiol Dehydrogenase Isoforms: Oxidation of trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene to the Activated o-Quinone Metabolite Benzo[a]pyrene-7,8-dione

Anti‐RNA polymerase antibodies in systemic sclerosis (SSc): association with anti‐topoisomerase I antibodies and identification of autoreactive subunits of RNA polymerase II

Metabolic activation of benzo[g]chrysene in the human mammary carcinoma cell line MCF-7

Generation of Reactive Oxygen Species during the Enzymatic Oxidation of Polycyclic Aromatic Hydrocarbon trans-Dihydrodiols Catalyzed by Dihydrodiol Dehydrogenase

Cytotoxicity of polycyclic aromatic hydrocarbon o-quinones in rat and human hepatoma cells

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