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Irinotecan in the Treatment of Colorectal Cancer: Clinical Overview

Journal of clinical oncology, 2001-03, Vol.19 (5), p.1501-1518

2001

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Preliminary biomarker and pharmacokinetic analysis from the completed dose escalation part of the first-in-human Phase I study evaluating MP0250, a multi-DARPin® blocking HGF and VEGF-A, in patients with advanced solid tumors

European journal of cancer (1990), 2016-12, Vol.69, p.S133-S133

2016

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Preoperative chemotherapy followed by concurrent chemoradiation therapy based on hyperfractionated accelerated radiotherapy and definitive surgery in locally advanced non-small-cell lung cancer: mature results of a phase II trial

Journal of clinical oncology, 1998-02, Vol.16 (2), p.622-634

1998

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First-Line High-Dose Chemotherapy Compared With Standard-Dose PEB/VIP Chemotherapy in Patients With Advanced Germ Cell Tumors: A Multivariate and Matched-Pair Analysis

Journal of clinical oncology, 1999-11, Vol.17 (11), p.3450-3456

1999

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Different classes of EGFR inhibitors may have different potential to improve local tumour control after fractionated irradiation: a study on C225 in FaDu hSCC

Radiotherapy and oncology, 2005-02, Vol.74 (2), p.109-115

2005

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Gemcitabine in Patients With Relapsed or Cisplatin-Refractory Testicular Cancer

Journal of clinical oncology, 1999-02, Vol.17 (2), p.512-516

1999

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Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors

Journal of clinical oncology, 1997-01, Vol.15 (1), p.389-400

1997

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Secondary leukemia following high cumulative doses of etoposide in patients treated for advanced germ cell tumors

Journal of clinical oncology, 1998-10, Vol.16 (10), p.3386-3391

1998

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Phase I/II study of capecitabine and vinorelbine in pretreated patients with metastatic breast cancer

Annals of oncology, 2005-01, Vol.16 (1), p.64-69

2005

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Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer

The New England journal of medicine, 2004-07, Vol.351 (4), p.337-345

2004

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Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study

Annals of oncology, 2003-09, Vol.14 (9), p.1442-1448

2003

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Phase II Multicenter Study of the Antiepidermal Growth Factor Receptor Monoclonal Antibody Cetuximab in Combination With Platinum-Based Chemotherapy in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck

Journal of clinical oncology, 2005-08, Vol.23 (24), p.5568-5577

2005

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Phase I clinical and pharmacokinetic study of titanocene dichloride in adults with advanced solid tumors

Clinical cancer research, 1998-11, Vol.4 (11), p.2701-2708

1998

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Future treatment options with capecitabine

Seminars in oncology, 2000-10, Vol.27 (5), p.149-152

HARSTRICK, Andreas

2000

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Phase II study of paclitaxel in patients with relapsed or cisplatin-refractory testicular cancer

Annals of oncology, 1996-01, Vol.7 (1), p.31-34

1996

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Comparative antitumor efficacy of docetaxel and paclitaxel in nude mice bearing human tumor xenografts that overexpress the multidrug resistance protein (MRP)

Annals of oncology, 1997-12, Vol.8 (12), p.1221-1228

1997

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Phase I Study of the Humanized Antiepidermal Growth Factor Receptor Monoclonal Antibody EMD72000 in Patients With Advanced Solid Tumors That Express the Epidermal Growth Factor Receptor

Journal of clinical oncology, 2004-01, Vol.22 (1), p.175-184

2004

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A randomized trial of cisplatin, etoposide and bleomycin (PEB) versus carboplatin, etoposide and bleomycin (CEB) for patients with 'good-risk' metastatic non-seminomatous germ cell tumors

Annals of oncology, 1996-12, Vol.7 (10), p.1015-1021

1996

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Abstract OT1-03-02: MP0274-CP101: A phase 1, first-in-human, single-arm, multi-center, open-label, dose escalation study to assess safety, tolerability, and pharmacokinetics of MP0274 in patients with advanced HER2-positive solid tumors

Cancer research (Chicago, Ill.), 2018-02, Vol.78 (4_Supplement), p.OT1-03-02-OT1-03-02

2018

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MP0250 – a dual inhibitor of VEGF and HGF - plus bortezomib + dexamethasone in a phase 2 open-label, single-arm, multicenter trial in patients with refractory and relapsed multiple myeloma (RRMM)

Annals of oncology, 2017-09, Vol.28, p.v371-v371

2017

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Comparison between short or long exposure to 5-fluorouracil in human gastric and colon cancer cell lines: biochemical mechanism of resistance

Anti-cancer drugs, 1998-08, Vol.9 (7), p.625-634

1998

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High-dose chemotherapy with autologous stem cell transplantation in patients with oligometastatic breast cancer

Bone marrow transplantation (Basingstoke), 2004-10, Vol.34 (7), p.637-643

2004

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Ifosfamide-based drug combinations : Preclinical evaluation of drug interactions and translation into the clinic

Seminars in oncology, 2000-02, Vol.27 (1), p.8-13

2000

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406 - Preliminary biomarker and pharmacokinetic analysis from the completed dose escalation part of the first-in-human Phase I study evaluating MP0250, a multi-DARPin® blocking HGF and VEGF-A, in patients with advanced solid tumors

European journal of cancer (1990), 2016-12, Vol.69, p.S133-S133

2016

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Interim results from the completed first-in-human phase I dose escalation study evaluating MP0250, a multi-DARPin® blocking HGF and VEGF, in patients with advanced solid tumors

Annals of oncology, 2016-10, Vol.27, p.vi115-vi115

2016

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Irinotecan in the Treatment of Colorectal Cancer: Clinical Overview

Preliminary biomarker and pharmacokinetic analysis from the completed dose escalation part of the first-in-human Phase I study evaluating MP0250, a multi-DARPin® blocking HGF and VEGF-A, in patients with advanced solid tumors

Preoperative chemotherapy followed by concurrent chemoradiation therapy based on hyperfractionated accelerated radiotherapy and definitive surgery in locally advanced non-small-cell lung cancer: mature results of a phase II trial

First-Line High-Dose Chemotherapy Compared With Standard-Dose PEB/VIP Chemotherapy in Patients With Advanced Germ Cell Tumors: A Multivariate and Matched-Pair Analysis

Different classes of EGFR inhibitors may have different potential to improve local tumour control after fractionated irradiation: a study on C225 in FaDu hSCC

Gemcitabine in Patients With Relapsed or Cisplatin-Refractory Testicular Cancer

Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors

Secondary leukemia following high cumulative doses of etoposide in patients treated for advanced germ cell tumors

Phase I/II study of capecitabine and vinorelbine in pretreated patients with metastatic breast cancer

Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer

Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study

Phase II Multicenter Study of the Antiepidermal Growth Factor Receptor Monoclonal Antibody Cetuximab in Combination With Platinum-Based Chemotherapy in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck

Phase I clinical and pharmacokinetic study of titanocene dichloride in adults with advanced solid tumors

Future treatment options with capecitabine

Phase II study of paclitaxel in patients with relapsed or cisplatin-refractory testicular cancer

Comparative antitumor efficacy of docetaxel and paclitaxel in nude mice bearing human tumor xenografts that overexpress the multidrug resistance protein (MRP)

Phase I Study of the Humanized Antiepidermal Growth Factor Receptor Monoclonal Antibody EMD72000 in Patients With Advanced Solid Tumors That Express the Epidermal Growth Factor Receptor

A randomized trial of cisplatin, etoposide and bleomycin (PEB) versus carboplatin, etoposide and bleomycin (CEB) for patients with 'good-risk' metastatic non-seminomatous germ cell tumors

Abstract OT1-03-02: MP0274-CP101: A phase 1, first-in-human, single-arm, multi-center, open-label, dose escalation study to assess safety, tolerability, and pharmacokinetics of MP0274 in patients with advanced HER2-positive solid tumors

MP0250 – a dual inhibitor of VEGF and HGF - plus bortezomib + dexamethasone in a phase 2 open-label, single-arm, multicenter trial in patients with refractory and relapsed multiple myeloma (RRMM)

Comparison between short or long exposure to 5-fluorouracil in human gastric and colon cancer cell lines: biochemical mechanism of resistance

High-dose chemotherapy with autologous stem cell transplantation in patients with oligometastatic breast cancer

Ifosfamide-based drug combinations : Preclinical evaluation of drug interactions and translation into the clinic

406 - Preliminary biomarker and pharmacokinetic analysis from the completed dose escalation part of the first-in-human Phase I study evaluating MP0250, a multi-DARPin® blocking HGF and VEGF-A, in patients with advanced solid tumors

Interim results from the completed first-in-human phase I dose escalation study evaluating MP0250, a multi-DARPin® blocking HGF and VEGF, in patients with advanced solid tumors

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