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Surface Proteomics Reveals CD72 as a Target for In Vitro -Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1 -Rearranged B-ALL

Cancer discovery, 2021-08, Vol.11 (8), p.2032-2049

2021

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Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells

The Journal of clinical investigation, 2016-12, Vol.126 (12), p.4640-4653

2016

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Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (11), p.5733-5740

2020

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Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors

The Journal of experimental medicine, 2022-04, Vol.219 (4)

2022

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Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

Nature, 2007-01, Vol.445 (7126), p.437-441

2007

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Development of a stress response therapy targeting aggressive prostate cancer

Science translational medicine, 2018-05, Vol.10 (439)

2018

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Pharmacological brake-release of mRNA translation enhances cognitive memory

eLife, 2013-05, Vol.2, p.e00498-e00498

2013

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Potent Activity of an Anti-ICAM1 Antibody-Drug Conjugate against Multiple Myeloma

Clinical cancer research, 2020-11, Vol.26 (22), p.6028-6038

2020

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Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer

Molecular cancer therapeutics, 2015-03, Vol.14 (3), p.642-648

2015

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MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma

Cancer research (Chicago, Ill.), 2017-08, Vol.77 (16), p.4498-4505

2017

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A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Cancer discovery, 2012-08, Vol.2 (8), p.685-693

2012

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Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment

Haematologica (Roma), 2018-07, Vol.103 (7), p.1218-1228

2018

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Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers

The Journal of clinical investigation, 2022-02, Vol.132 (4)

2022

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Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma

Nature communications, 2020-04, Vol.11 (1), p.1931-14, Article 1931

2020

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Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy

Cell reports (Cambridge), 2021-07, Vol.36 (1), p.109309-109309, Article 109309

2021

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Targeted Tumor Cell Internalization and Imaging of Multifunctional Quantum Dot-Conjugated Immunoliposomes in Vitro and in Vivo

Nano letters, 2008-09, Vol.8 (9), p.2851-2857

2008

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A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models

Journal of medicinal chemistry, 2016-12, Vol.59 (24), p.11161-11170

2016

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Picomolar sensitivity MRI and photoacoustic imaging of cobalt nanoparticles

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (11), p.4085-4089

2009

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Imaging a functional tumorigenic biomarker in the transformed epithelium

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.93-98

2013

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Targeting CD46 for both adenocarcinoma and neuroendocrine prostate cancer

JCI insight, 2018-09, Vol.3 (17)

2018

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Autophagy suppression promotes apoptotic cell death in response to inhibition of the PI3K—mTOR pathway in pancreatic adenocarcinoma

Journal of molecular medicine (Berlin, Germany), 2011-09, Vol.89 (9), p.877-889

2011

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High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions

mAbs, 2023, Vol.15 (1), p.2184197-2184197

2023

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Non-competitive androgen receptor inhibition in vitro and in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7233-7238

2009

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Oncogene Mimicry as a Mechanism of Primary Resistance to BRAF Inhibitors

Cell reports (Cambridge), 2014-08, Vol.8 (4), p.1037-1048

2014

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Development of a highly stable and targetable nanoliposomal formulation of topotecan

Journal of controlled release, 2010-01, Vol.141 (1), p.13-21

2010

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Surface Proteomics Reveals CD72 as a Target for In Vitro -Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1 -Rearranged B-ALL

Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells

Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation

Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors

Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

Development of a stress response therapy targeting aggressive prostate cancer

Pharmacological brake-release of mRNA translation enhances cognitive memory

Potent Activity of an Anti-ICAM1 Antibody-Drug Conjugate against Multiple Myeloma

Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer

MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma

A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers

Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma

Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy

Targeted Tumor Cell Internalization and Imaging of Multifunctional Quantum Dot-Conjugated Immunoliposomes in Vitro and in Vivo

A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models

Picomolar sensitivity MRI and photoacoustic imaging of cobalt nanoparticles

Imaging a functional tumorigenic biomarker in the transformed epithelium

Targeting CD46 for both adenocarcinoma and neuroendocrine prostate cancer

Autophagy suppression promotes apoptotic cell death in response to inhibition of the PI3K—mTOR pathway in pancreatic adenocarcinoma

High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions

Non-competitive androgen receptor inhibition in vitro and in vivo

Oncogene Mimicry as a Mechanism of Primary Resistance to BRAF Inhibitors

Development of a highly stable and targetable nanoliposomal formulation of topotecan

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