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Characterization of efflux transporters involved in distribution and disposition of apixaban

Drug metabolism and disposition, 2013-04, Vol.41 (4), p.827

2013

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Tolerability and pharmacokinetics of ginsenosides Rb1, Rb2, Rc, Rd, and compound K after single or multiple administration of red ginseng extract in human beings

Journal of Ginseng Research, 2020, 44(2), , pp.229-237

2020

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Peptide transporter substrate identification during permeability screening in drug discovery: Comparison of transfected MDCK-hPepT1 cells to caco-2 cells

Archives of pharmacal research, 2007-04, Vol.30 (4), p.507-518

2007

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PLAG (1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol) Modulates Eosinophil Chemotaxis by Regulating CCL26 Expression from Epithelial Cells

PloS one, 2016-03, Vol.11 (3), p.e0151758-e0151758

2016

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Effect of Red Ginseng Extract on the Pharmacokinetics and Efficacy of Metformin in Streptozotocin-Induced Diabetic Rats

Pharmaceutics, 2018-07, Vol.10 (3), p.80

2018

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Characterization of Organic Anion-Transporting Polypeptide (Oatp) 1a1 and 1a4 Null Mice Reveals Altered Transport Function and Urinary Metabolomic Profiles

Toxicological sciences, 2011-08, Vol.122 (2), p.587-597

2011

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Induction of heme oxygenase-1 (HO-1) and NAD[P]H : Quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert -butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes

Pharmaceutical research, 2006-11, Vol.23 (11), p.2586-2594

2006

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Cynomolgus monkey as a potential model to assess drug interactions involving hepatic organic anion transporting polypeptides: in vitro, in vivo, and in vitro-to-in vivo extrapolation

The Journal of pharmacology and experimental therapeutics, 2013-03, Vol.344 (3), p.673

2013

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A Comprehensive In Vivo and In Vitro Assessment of the Drug Interaction Potential of Red Ginseng

Clinical therapeutics, 2018-08, Vol.40 (8), p.1322-1337

2018

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Current industrial practices of assessing permeability and P-glycoprotein interaction

The AAPS journal, 2006-01, Vol.8 (1), p.E1-E13

2006

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Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro

Drug metabolism and disposition, 2016-03, Vol.44 (3), p.320-328

2016

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Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Journal of medicinal chemistry, 2014-03, Vol.57 (5), p.1708-1729

2014

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Human Renal Organic Anion Transporter 1-Dependent Uptake and Toxicity of Mercuric-Thiol Conjugates in Madin-Darby Canine Kidney Cells

Molecular pharmacology, 2003-03, Vol.63 (3), p.590-596

2003

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Pharmacokinetic drug interactions involving 17α-ethinylestradiol : A new look at an old drug

Clinical pharmacokinetics, 2007-02, Vol.46 (2), p.133-157

2007

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PLAG (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol) augments the therapeutic effect of pegfilgrastim on gemcitabine-induced neutropenia

Cancer letters, 2016-07, Vol.377 (1), p.25-31

2016

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Protective effect of EC-18, a synthetic monoacetyldiglyceride on lung inflammation in a murine model induced by cigarette smoke and lipopolysaccharide

International immunopharmacology, 2016-01, Vol.30, p.62-68

2016

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Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.8042-8060

2016

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Involvement of P-glycoprotein, Multidrug Resistance Protein 2 and Breast Cancer Resistance Protein in the Transport of Belotecan and Topotecan in Caco-2 and MDCKII Cells

Pharmaceutical research, 2008-11, Vol.25 (11), p.2601-2612

2008

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Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: Association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium

Journal of pharmaceutical sciences, 2005-12, Vol.94 (12), p.2644-2655

2005

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Phenobarbital Alters Hepatic Mrp2 Function by Direct and Indirect Interactions

Molecular pharmacology, 2003-07, Vol.64 (1), p.154-159

2003

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Development of novel, 384-well high-throughput assay panels for human drug transporters: drug interaction and safety assessment in support of discovery research

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1072-1083

2013

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Contribution of ion-pair complexation with bile salts to the transport of organic cations across LLC-PK1 cell monolayers

Pharmaceutical research, 2003-04, Vol.20 (4), p.597-604

2003

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1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression

Immune Network, 2015, 15(2), , pp.100-109

2015

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Effect of interferon-α2b on the expression of various drug-metabolizing enzymes and transporters in co-cultures of freshly prepared human primary hepatocytes

Xenobiotica, 2011-06, Vol.41 (6), p.476-485

2011

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Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells

American journal of physiology. Renal physiology, 2003-10, Vol.285 (4), p.F775-F783

2003

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Characterization of efflux transporters involved in distribution and disposition of apixaban

Tolerability and pharmacokinetics of ginsenosides Rb1, Rb2, Rc, Rd, and compound K after single or multiple administration of red ginseng extract in human beings

Peptide transporter substrate identification during permeability screening in drug discovery: Comparison of transfected MDCK-hPepT1 cells to caco-2 cells

PLAG (1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol) Modulates Eosinophil Chemotaxis by Regulating CCL26 Expression from Epithelial Cells

Effect of Red Ginseng Extract on the Pharmacokinetics and Efficacy of Metformin in Streptozotocin-Induced Diabetic Rats

Characterization of Organic Anion-Transporting Polypeptide (Oatp) 1a1 and 1a4 Null Mice Reveals Altered Transport Function and Urinary Metabolomic Profiles

Induction of heme oxygenase-1 (HO-1) and NAD[P]H : Quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert -butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes

Cynomolgus monkey as a potential model to assess drug interactions involving hepatic organic anion transporting polypeptides: in vitro, in vivo, and in vitro-to-in vivo extrapolation

A Comprehensive In Vivo and In Vitro Assessment of the Drug Interaction Potential of Red Ginseng

Current industrial practices of assessing permeability and P-glycoprotein interaction

Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro

Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Human Renal Organic Anion Transporter 1-Dependent Uptake and Toxicity of Mercuric-Thiol Conjugates in Madin-Darby Canine Kidney Cells

Pharmacokinetic drug interactions involving 17α-ethinylestradiol : A new look at an old drug

PLAG (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol) augments the therapeutic effect of pegfilgrastim on gemcitabine-induced neutropenia

Protective effect of EC-18, a synthetic monoacetyldiglyceride on lung inflammation in a murine model induced by cigarette smoke and lipopolysaccharide

Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing

Involvement of P-glycoprotein, Multidrug Resistance Protein 2 and Breast Cancer Resistance Protein in the Transport of Belotecan and Topotecan in Caco-2 and MDCKII Cells

Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: Association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium

Phenobarbital Alters Hepatic Mrp2 Function by Direct and Indirect Interactions

Development of novel, 384-well high-throughput assay panels for human drug transporters: drug interaction and safety assessment in support of discovery research

Contribution of ion-pair complexation with bile salts to the transport of organic cations across LLC-PK1 cell monolayers

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression

Effect of interferon-α2b on the expression of various drug-metabolizing enzymes and transporters in co-cultures of freshly prepared human primary hepatocytes

Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells

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