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Disease–Drug Interactions in Inflammatory States via Effects on CYP‐Mediated Drug Clearance

Journal of clinical pharmacology, 2018-07, Vol.58 (7), p.849-863

2018

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Abemaciclib Inhibits Renal Tubular Secretion Without Changing Glomerular Filtration Rate

Clinical pharmacology and therapeutics, 2019-05, Vol.105 (5), p.1187-1195

2019

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Exploring the Feasibility of Bidirectional Control of Beta Oscillatory Power in Healthy Controls as a Potential Intervention for Parkinson’s Disease Movement Impairment

Sensors (Basel, Switzerland), 2024-08, Vol.24 (16), p.5107

2024

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The Risky Side of Creativity: Domain Specific Risk Taking in Creative Individuals

Frontiers in psychology, 2017-02, Vol.8, p.145-145

2017

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Predicting Clinical Effects of CYP3A4 Modulators on Abemaciclib and Active Metabolites Exposure Using Physiologically Based Pharmacokinetic Modeling

Journal of clinical pharmacology, 2020-07, Vol.60 (7), p.915-930

2020

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Prediction of the Renal Organic Anion Transporter 1 (OAT1)- Mediated Drug Interactions for LY404039, the Active Metabolite of Pomaglumetad Methionil

Pharmaceutical research, 2023-11, Vol.40 (11), p.2499-2511

2023

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Quantitative Structure–Activity Relationship Models of Clinical Pharmacokinetics: Clearance and Volume of Distribution

Journal of chemical information and modeling, 2013-04, Vol.53 (4), p.948-957

2013

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Mechanistic understanding of the phase behavior of supersaturated solutions of poorly water-soluble drugs

International journal of pharmaceutics, 2018-05, Vol.543 (1-2), p.29-37

2018

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Neuronal network pharmacodynamics of GABAergic modulation in the human cortex determined using pharmaco-magnetoencephalography

Human brain mapping, 2010-04, Vol.31 (4), p.581-594

2010

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Sustained neuronal activity generated by glial plasticity

The Journal of neuroscience, 2011-05, Vol.31 (21), p.7637-7647

2011

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Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions

PLoS computational biology, 2012-08, Vol.8 (8), p.e1002614

2012

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Monitoring the Phase Behavior of Supersaturated Solutions of Poorly Water-Soluble Drugs Using Fluorescence Techniques

Journal of pharmaceutical sciences, 2018-01, Vol.107 (1), p.94-102

2018

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Quantitative Prediction of CYP3A4‐ and CYP3A5‐Mediated Drug Interactions

Clinical pharmacology and therapeutics, 2020-01, Vol.107 (1), p.246-256

2020

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Prediction of renal transporter mediated drug-drug interactions for pemetrexed using physiologically based pharmacokinetic modeling

Drug metabolism and disposition, 2015-03, Vol.43 (3), p.325-334

2015

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The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

The Journal of pharmacology and experimental therapeutics, 2003-07, Vol.306 (1), p.287-300

2003

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Nature genetics, 2001-04, Vol.27 (4), p.383-391

2001

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Hepatic Organic Anion Transporting Polypeptide-Mediated Clearance in the Beagle Dog: Assessing In Vitro-In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance

Drug metabolism and disposition, 2019-03, Vol.47 (3), p.215-226

2019

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Prediction of Transporter‐Mediated Drug‐Drug Interactions for Baricitinib

Clinical and translational science, 2017-11, Vol.10 (6), p.509-519

2017

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Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America

Clinical infectious diseases, 2005-06, Vol.40 (11), p.1559-1585

2005

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The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2C9 and CYP3A4 Substrates

Drug metabolism and disposition, 2017-09, Vol.45 (9), p.1008-1018

2017

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Semiphysiologically based pharmacokinetic models for the inhibition of midazolam clearance by diltiazem and its major metabolite

Drug metabolism and disposition, 2009-08, Vol.37 (8), p.1587-1597

2009

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Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model

CPT: pharmacometrics and systems pharmacology, 2019-09, Vol.8 (9), p.685-695

2019

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Mechanism-based inactivation of CYP3A by HIV protease inhibitors

The Journal of pharmacology and experimental therapeutics, 2005-02, Vol.312 (2), p.583-591

2005

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Exhaled Air Dispersion Distances During Noninvasive Ventilation via Different Respironics Face Masks

Chest, 2009-10, Vol.136 (4), p.998-1005

2009

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Prediction of cytochrome P450 3A inhibition by verapamil enantiomers and their metabolites

Drug metabolism and disposition, 2004-02, Vol.32 (2), p.259-266

2004

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Disease–Drug Interactions in Inflammatory States via Effects on CYP‐Mediated Drug Clearance

Abemaciclib Inhibits Renal Tubular Secretion Without Changing Glomerular Filtration Rate

Exploring the Feasibility of Bidirectional Control of Beta Oscillatory Power in Healthy Controls as a Potential Intervention for Parkinson’s Disease Movement Impairment

The Risky Side of Creativity: Domain Specific Risk Taking in Creative Individuals

Predicting Clinical Effects of CYP3A4 Modulators on Abemaciclib and Active Metabolites Exposure Using Physiologically Based Pharmacokinetic Modeling

Prediction of the Renal Organic Anion Transporter 1 (OAT1)- Mediated Drug Interactions for LY404039, the Active Metabolite of Pomaglumetad Methionil

Quantitative Structure–Activity Relationship Models of Clinical Pharmacokinetics: Clearance and Volume of Distribution

Mechanistic understanding of the phase behavior of supersaturated solutions of poorly water-soluble drugs

Neuronal network pharmacodynamics of GABAergic modulation in the human cortex determined using pharmaco-magnetoencephalography

Sustained neuronal activity generated by glial plasticity

Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions

Monitoring the Phase Behavior of Supersaturated Solutions of Poorly Water-Soluble Drugs Using Fluorescence Techniques

Quantitative Prediction of CYP3A4‐ and CYP3A5‐Mediated Drug Interactions

Prediction of renal transporter mediated drug-drug interactions for pemetrexed using physiologically based pharmacokinetic modeling

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Hepatic Organic Anion Transporting Polypeptide-Mediated Clearance in the Beagle Dog: Assessing In Vitro-In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance

Prediction of Transporter‐Mediated Drug‐Drug Interactions for Baricitinib

Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America

The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2C9 and CYP3A4 Substrates

Semiphysiologically based pharmacokinetic models for the inhibition of midazolam clearance by diltiazem and its major metabolite

Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model

Mechanism-based inactivation of CYP3A by HIV protease inhibitors

Exhaled Air Dispersion Distances During Noninvasive Ventilation via Different Respironics Face Masks

Prediction of cytochrome P450 3A inhibition by verapamil enantiomers and their metabolites

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