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A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent, partially platinum-sensitive ovarian cancer

British journal of cancer, 2014-04, Vol.110 (8), p.1923-1929

2014

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Exon 3 β-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome

Gut, 2005-02, Vol.54 (2), p.264-267

2005

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How do site-specific DNA-binding proteins find their targets?

Nucleic acids research, 2004, Vol.32 (10), p.3040-3052

2004

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The identification of chemical intermediates in enzyme catalysis by the rapid quench-flow technique

Cellular and molecular life sciences : CMLS, 2006-11, Vol.63 (22), p.2571-2583

2006

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Hopping, jumping and looping by restriction enzymes

Biochemical Society transactions, 2001-08, Vol.29 (Pt 4), p.363-373

Halford, S E

2001

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Repercussions of DNA tracking by the type IC restriction endonuclease EcoR124I on linear, circular and catenated substrates

The EMBO journal, 1996-11, Vol.15 (22), p.6335-6347

1996

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Recombination by resolvase to analyse DNA communications by the SfiI restriction endonuclease

The EMBO journal, 1996-03, Vol.15 (6), p.1460-1469

1996

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EcoRV restriction endonuclease binds all DNA sequences with equal affinity

Biochemistry (Easton), 1991-09, Vol.30 (36), p.8743-8753

1991

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One- and three-dimensional pathways for proteins to reach specific DNA sites

The EMBO journal, 2000-12, Vol.19 (23), p.6546-6557

2000

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EcoRV restriction endonuclease: communication between catalytic metal ions and DNA recognition

Biochemistry (Easton), 1992-07, Vol.31 (26), p.6082-6089

1992

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Discrimination between DNA sequences by the EcoRV restriction endonuclease

Biochemistry (Easton), 1989-07, Vol.28 (15), p.6198-6207

1989

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DNA cleavage reactions by type II restriction enzymes that require two copies of their recognition sites

Journal of molecular biology, 2001-08, Vol.311 (3), p.503-514

2001

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Dynamics of long-range interactions on DNA: The speed of synapsis during site-specific recombination by resolvase

Cell, 1991-08, Vol.66 (4), p.781-791

1991

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Restriction endonuclease reactions requiring two recognition sites

Biochemical Society transactions, 1999-08, Vol.27 (4), p.696-699

1999

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EcoRV restriction endonuclease: communication between DNA recognition and catalysis

Biochemistry (Easton), 1992-07, Vol.31 (26), p.6089-6097

1992

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The activity of the EcoRV restriction endonuclease is influenced by flanking DNA sequences both inside and outside the DNA-protein complex

Biochemistry (Easton), 1992-01, Vol.31 (1), p.90-97

1992

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Modes of DNA cleavage by the EcoRV restriction endonuclease

Biochemistry (Easton), 1988-03, Vol.27 (5), p.1771-1777

1988

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Specific DNA Recognition by EcoRV Restriction Endonuclease Induced by Calcium Ions

Biochemistry (Easton), 1995, Vol.34 (4), p.1113-1119

1995

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Divalent Metal Ions at the Active Sites of the EcoRV and EcoRI Restriction Endonucleases

Biochemistry (Easton), 1995-01, Vol.34 (2), p.697-704

1995

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DNA cleavage by the EcoRV restriction endonuclease: roles of divalent metal ions in specificity and catalysis

Journal of molecular biology, 1999-04, Vol.288 (1), p.87-103

1999

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Recombination: Pieces of the site-specific recombination puzzle

Current biology, 1995-10, Vol.5 (10), p.1106-1109

1995

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The SfiI restriction endonuclease makes a four-strand DNA break at two copies of its recognition sequence

Journal of molecular biology, 1995-05, Vol.248 (3), p.581-595

1995

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Specificity of DNA recognition in the nucleoprotein complex for site-specific recombination by Tn21 resolvase

Nucleic acids research, 1993-12, Vol.21 (24), p.5712-5719

1993

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Reactions of Type II Restriction Endonucleases with 8-Base Pair Recognition Sites

The Journal of biological chemistry, 1999-12, Vol.274 (51), p.36379-36386

1999

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Analysis of DNA looping interactions by type II restriction enzymes that require two copies of their recognition sites

Journal of molecular biology, 2001-08, Vol.311 (3), p.515-527

2001

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A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent, partially platinum-sensitive ovarian cancer

Exon 3 β-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome

How do site-specific DNA-binding proteins find their targets?

The identification of chemical intermediates in enzyme catalysis by the rapid quench-flow technique

Hopping, jumping and looping by restriction enzymes

Repercussions of DNA tracking by the type IC restriction endonuclease EcoR124I on linear, circular and catenated substrates

Recombination by resolvase to analyse DNA communications by the SfiI restriction endonuclease

EcoRV restriction endonuclease binds all DNA sequences with equal affinity

One- and three-dimensional pathways for proteins to reach specific DNA sites

EcoRV restriction endonuclease: communication between catalytic metal ions and DNA recognition

Discrimination between DNA sequences by the EcoRV restriction endonuclease

DNA cleavage reactions by type II restriction enzymes that require two copies of their recognition sites

Dynamics of long-range interactions on DNA: The speed of synapsis during site-specific recombination by resolvase

Restriction endonuclease reactions requiring two recognition sites

EcoRV restriction endonuclease: communication between DNA recognition and catalysis

The activity of the EcoRV restriction endonuclease is influenced by flanking DNA sequences both inside and outside the DNA-protein complex

Modes of DNA cleavage by the EcoRV restriction endonuclease

Specific DNA Recognition by EcoRV Restriction Endonuclease Induced by Calcium Ions

Divalent Metal Ions at the Active Sites of the EcoRV and EcoRI Restriction Endonucleases

DNA cleavage by the EcoRV restriction endonuclease: roles of divalent metal ions in specificity and catalysis

Recombination: Pieces of the site-specific recombination puzzle

The SfiI restriction endonuclease makes a four-strand DNA break at two copies of its recognition sequence

Specificity of DNA recognition in the nucleoprotein complex for site-specific recombination by Tn21 resolvase

Reactions of Type II Restriction Endonucleases with 8-Base Pair Recognition Sites

Analysis of DNA looping interactions by type II restriction enzymes that require two copies of their recognition sites

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