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Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences

Journal of molecular biology, 2004-01, Vol.335 (2), p.547-554

2004

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Non-Peptide Glycoprotein IIb/IIIa Antagonists. 11. Design and in Vivo Evaluation of 3,4-Dihydro-1(1H)-isoquinolinone-Based Antagonists and Ethyl Ester Prodrugs

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4583-4591

1996

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Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences

Journal of molecular biology, 2010-11, Vol.335 ((2) ; 01, 2004)

2010

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Nonpeptide αvβ3 Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent αvβ3 Antagonist for the Prevention and Treatment of Osteoporosis

Journal of medicinal chemistry, 2003-10, Vol.46 (22), p.4790-4798

2003

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Nonpeptide glycoprotein IIB/IIIA inhibitors. 12. Potent and orally active centrally constrained thieno[2,3-c]pyridones

Bioorganic & medicinal chemistry letters, 1996-11, Vol.6 (22), p.2771-2776

1996

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Non-Peptide Fibrinogen Receptor Antagonists. 2. Optimization of a Tyrosine Template as a Mimic for Arg-Gly-Asp

Journal of medicinal chemistry, 1994-08, Vol.37 (16), p.2537-2551

1994

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Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors

Journal of medicinal chemistry, 1992-11, Vol.35 (24), p.4640-4642

1992

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Nonpeptide αvβ3 antagonists. Part 10: in vitro and in vivo evaluation of a potent 7-methyl substituted tetrahydro-[1,8]naphthyridine derivative

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4515-4518

2004

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Nonpeptide α vβ 3 antagonists. Part 9: Improved pharmacokinetic profile through the use of an aliphatic, des-amide backbone

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4411-4415

2004

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Nonpeptide α vβ 3 antagonists. Part 10: In vitro and in vivo evaluation of a potent 7-methyl substituted tetrahydro-[1,8]naphthyridine derivative

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4515-4518

2004

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Benzocycloheptapyridines. Analogs of azatadine

Journal of heterocyclic chemistry, 1986-01, Vol.23 (1), p.257-263

1986

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Nonpeptide αvβ3 antagonists. Part 9: Improved pharmacokinetic profile through the use of an aliphatic, des-amide backbone

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4411-4415

2004

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Non-peptide alphavbeta3 antagonists. Part 6: design and synthesis of alphavbeta3 antagonists containing a pyridone or pyrazinone central scaffold

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1809

2003

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Synthesis of 9,10-dihydroanthracen-9,10-imines

Journal of organic chemistry, 1979-04, Vol.44 (9), p.1519-1533

1979

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Non-peptide αvβ3 antagonists. Part 6: Design and synthesis of αvβ3 antagonists containing a pyridone or pyrazinone central scaffold

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1809-1812

2003

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Iminium-ion-mediated cyclizations of 4-aryl-1,4-dihydropyridines. Regio- and stereoselectivity in intermolecular reactions

Journal of organic chemistry, 1987-03, Vol.52 (6), p.1136-1139

1987

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Nonpeptide alphavbeta3 antagonists. 8. In vitro and in vivo evaluation of a potent alphavbeta3 antagonist for the prevention and treatment of osteoporosis

Journal of medicinal chemistry, 2003-10, Vol.46 (22), p.4790-4798

2003

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Nonpeptide α v β 3 Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent α v β 3 Antagonist for the Prevention and Treatment of Osteoporosis

Journal of medicinal chemistry, 2003-10, Vol.46 (22), p.4790-4798

2003

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Non-Peptide α vβ 3 antagonists. Part 6: Design and synthesis of α vβ 3 antagonists containing a pyridone or pyrazinone central scaffold

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (10), p.1809-1812

2003

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alpha.-Adrenergic activities of some substituted 2-(aminomethyl)imidazolines

Journal of medicinal chemistry, 1983-12, Vol.26 (12), p.1769-1772

1983

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Fibrinogen receptor antagonists

Transfusion science, 1994-03, Vol.15 (1), p.ii-ii

1994

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3-Hydroxy-.alpha.-methyltyrosine progenitors, synthesis and evaluation of some (2-oxo-1,3-dioxol-4-yl)methyl esters

Journal of medicinal chemistry, 1984-06, Vol.27 (6), p.713-717

1984

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Pyridinylpiperazines, a new class of selective .alpha.2-adrenoceptor antagonists

Journal of medicinal chemistry, 1983-12, Vol.26 (12), p.1696-1701

1983

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Nonpeptide glycoprotein IIb/IIIa inhibitors: 18. Indole alpha-sulfonamide acids are potent inhibitors of platelet aggregation

Bioorganic & medicinal chemistry letters, 1997-11, Vol.7 (21), p.2793-2798

1997

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Studies Directed Toward the Regioselective Carboxylation of the 4-Oxo-4,5,6,7-Tetrahydrothieno-[3,2-C]pyridine Ring System

Synthetic communications, 1996-04, Vol.26 (7), p.1363-1370

1996

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Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences

Non-Peptide Glycoprotein IIb/IIIa Antagonists. 11. Design and in Vivo Evaluation of 3,4-Dihydro-1(1H)-isoquinolinone-Based Antagonists and Ethyl Ester Prodrugs

Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences

Nonpeptide αvβ3 Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent αvβ3 Antagonist for the Prevention and Treatment of Osteoporosis

Nonpeptide glycoprotein IIB/IIIA inhibitors. 12. Potent and orally active centrally constrained thieno[2,3-c]pyridones

Non-Peptide Fibrinogen Receptor Antagonists. 2. Optimization of a Tyrosine Template as a Mimic for Arg-Gly-Asp

Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors

Nonpeptide αvβ3 antagonists. Part 10: in vitro and in vivo evaluation of a potent 7-methyl substituted tetrahydro-[1,8]naphthyridine derivative

Nonpeptide α vβ 3 antagonists. Part 9: Improved pharmacokinetic profile through the use of an aliphatic, des-amide backbone

Nonpeptide α vβ 3 antagonists. Part 10: In vitro and in vivo evaluation of a potent 7-methyl substituted tetrahydro-[1,8]naphthyridine derivative

Benzocycloheptapyridines. Analogs of azatadine

Nonpeptide αvβ3 antagonists. Part 9: Improved pharmacokinetic profile through the use of an aliphatic, des-amide backbone

Non-peptide alphavbeta3 antagonists. Part 6: design and synthesis of alphavbeta3 antagonists containing a pyridone or pyrazinone central scaffold

Synthesis of 9,10-dihydroanthracen-9,10-imines

Non-peptide αvβ3 antagonists. Part 6: Design and synthesis of αvβ3 antagonists containing a pyridone or pyrazinone central scaffold

Iminium-ion-mediated cyclizations of 4-aryl-1,4-dihydropyridines. Regio- and stereoselectivity in intermolecular reactions

Nonpeptide alphavbeta3 antagonists. 8. In vitro and in vivo evaluation of a potent alphavbeta3 antagonist for the prevention and treatment of osteoporosis

Nonpeptide α v β 3 Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent α v β 3 Antagonist for the Prevention and Treatment of Osteoporosis

Non-Peptide α vβ 3 antagonists. Part 6: Design and synthesis of α vβ 3 antagonists containing a pyridone or pyrazinone central scaffold

alpha.-Adrenergic activities of some substituted 2-(aminomethyl)imidazolines

Fibrinogen receptor antagonists

3-Hydroxy-.alpha.-methyltyrosine progenitors, synthesis and evaluation of some (2-oxo-1,3-dioxol-4-yl)methyl esters

Pyridinylpiperazines, a new class of selective .alpha.2-adrenoceptor antagonists

Nonpeptide glycoprotein IIb/IIIa inhibitors: 18. Indole alpha-sulfonamide acids are potent inhibitors of platelet aggregation

Studies Directed Toward the Regioselective Carboxylation of the 4-Oxo-4,5,6,7-Tetrahydrothieno-[3,2-C]pyridine Ring System

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