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ABC transporters in cancer: more than just drug efflux pumps

Nature reviews. Cancer, 2010-02, Vol.10 (2), p.147

2010

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Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition

Drug resistance updates, 2021-12, Vol.59, p.100795-100795, Article 100795

2021

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Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

Cancer research (Chicago, Ill.), 2020-10, Vol.80 (19), p.4129-4144

2020

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The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35

Nature communications, 2019-11, Vol.10 (1), p.5026-17, Article 5026

2019

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A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4), p.971-981

2017

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Role of the MRP1/ABCC1 Multidrug Transporter Protein in Cancer

IUBMB life, 2007, Vol.59 (12), p.752-757

2007

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Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas

Nature communications, 2021-02, Vol.12 (1), p.971-13, Article 971

2021

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Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma

British journal of cancer, 2018-09, Vol.119 (6), p.693-696

2018

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Potent antileukemic activity of curaxin CBL0137 against MLL‐rearranged leukemia

International journal of cancer, 2020-04, Vol.146 (7), p.1902-1916

2020

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JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

Nature communications, 2019-07, Vol.10 (1), p.3319-15, Article 3319

2019

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The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression

Oncotarget, 2016-02, Vol.7 (8), p.8663-8675

2016

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The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Nature communications, 2024-02, Vol.15 (1), p.1385-1385, Article 1385

2024

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Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

Cancer research (Chicago, Ill.), 2018-06, Vol.78 (12), p.3122-3134

2018

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Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres

Cell reports (Cambridge), 2017-06, Vol.19 (12), p.2544-2556

2017

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ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

JNCI : Journal of the National Cancer Institute, 2011-08, Vol.103 (16), p.1236-1251

2011

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MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

Cancer research (Chicago, Ill.), 2016-06, Vol.76 (12), p.3604-3617

2016

Volltextzugriff (PDF)

The RNA‐helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma

Molecular oncology, 2021-04, Vol.15 (4), p.1162-1179

2021

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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

Cell reports (Cambridge), 2021-04, Vol.35 (2), p.108994-108994, Article 108994

2021

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Suppression of the ABCA1 Cholesterol Transporter Impairs the Growth and Migration of Epithelial Ovarian Cancer

Cancers, 2022-04, Vol.14 (8), p.1878

2022

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High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

Biochemical pharmacology, 2014-09, Vol.91 (1), p.97-108

2014

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Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma

International journal of molecular sciences, 2023-11, Vol.24 (21), p.15571

2023

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The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1

Oncotarget, 2014-04, Vol.5 (7), p.1793-1804

2014

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Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes

Scientific reports, 2023-03, Vol.13 (1), p.3775-3775, Article 3775

2023

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SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability

PLoS genetics, 2011-06, Vol.7 (6), p.e1002135-e1002135

2011

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ABC transporters in cancer: more than just drug efflux pumps

Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition

Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35

A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers

Role of the MRP1/ABCC1 Multidrug Transporter Protein in Cancer

Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas

Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma

Potent antileukemic activity of curaxin CBL0137 against MLL‐rearranged leukemia

Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres

ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin

The RNA‐helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma

Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

Suppression of the ABCA1 Cholesterol Transporter Impairs the Growth and Migration of Epithelial Ovarian Cancer

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1

Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes

SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability

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