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The p53 network: cellular and systemic DNA damage responses in aging and cancer

Trends in genetics, 2012-03, Vol.28 (3), p.128-136

2012

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Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response

Nature reviews. Molecular cell biology, 2013-09, Vol.14 (9), p.563-580

2013

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Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches

Trends in genetics, 2014-08, Vol.30 (8), p.326-339

2014

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Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes

Nature communications, 2021-04, Vol.12 (1), p.2048-2048, Article 2048

2021

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Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer

Cancer research (Chicago, Ill.), 2018-08, Vol.78 (15), p.4270-4281

2018

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Targeting CD38 in acute myeloid leukemia interferes with leukemia trafficking and induces phagocytosis

Scientific reports, 2021-11, Vol.11 (1), p.22062-22062, Article 22062

2021

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Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer

Scientific reports, 2017-11, Vol.7 (1), p.15511-16, Article 15511

2017

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p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage

Cancer cell, 2007-02, Vol.11 (2), p.175-189

2007

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Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints

Nature communications, 2020-08, Vol.11 (1), p.4124-4124, Article 4124

2020

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Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression

PloS one, 2015-05, Vol.10 (5), p.e0125745

2015

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DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

Molecular cell, 2010-10, Vol.40 (1), p.34-49

2010

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Data-driven grading of acute graft-versus-host disease

Nature communications, 2023-11, Vol.14 (1), p.7799-7799, Article 7799

2023

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Exploiting synthetic lethal interactions for targeted cancer therapy

Cell cycle (Georgetown, Tex.), 2009-10, Vol.8 (19), p.3112-3119

2009

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A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo

Cell reports (Cambridge), 2013-11, Vol.5 (4), p.868-877

2013

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CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization

Molecular cancer therapeutics, 2022-05, Vol.21 (5), p.821-830

2022

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NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

The Journal of cell biology, 2011-05, Vol.193 (4), p.633-642

2011

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Pericentromeric Satellite III transcripts induce etoposide resistance

Cell death & disease, 2021-05, Vol.12 (6), p.530-15, Article 530

2021

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Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia

Nature communications, 2017-07, Vol.8 (1), p.153-13, Article 153

2017

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Factor IX p.A37V mutation causes severe bleeding in a patient with phenprocoumon therapy

European journal of medical research, 2021-06, Vol.26 (1), p.63-63, Article 63

2021

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Biallelic variants in YRDC cause a developmental disorder with progeroid features

Human genetics, 2021-12, Vol.140 (12), p.1679-1693

2021

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Cytokine-Induced Signaling Networks Prioritize Dynamic Range over Signal Strength

Cell, 2008-10, Vol.135 (2), p.343-354

2008

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The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ

Human molecular genetics, 2012-12, Vol.21 (26), p.5528-5538

2012

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Low Soluble Programmed Cell Death Protein 1 Levels After Allogeneic Stem Cell Transplantation Predict Moderate or Severe Chronic GvHD and Inferior Overall Survival

Frontiers in immunology, 2021-09, Vol.12, p.694843-694843

2021

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A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC

Cancer discovery, 2014-05, Vol.4 (5), p.592-605

2014

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The p53 network: cellular and systemic DNA damage responses in aging and cancer

Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response

Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches

Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes

Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer

A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer

Targeting CD38 in acute myeloid leukemia interferes with leukemia trafficking and induces phagocytosis

Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer

p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage

Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints

Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

Data-driven grading of acute graft-versus-host disease

Exploiting synthetic lethal interactions for targeted cancer therapy

A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo

CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

Pericentromeric Satellite III transcripts induce etoposide resistance

Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia

Factor IX p.A37V mutation causes severe bleeding in a patient with phenprocoumon therapy

Biallelic variants in YRDC cause a developmental disorder with progeroid features

Cytokine-Induced Signaling Networks Prioritize Dynamic Range over Signal Strength

The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ

Low Soluble Programmed Cell Death Protein 1 Levels After Allogeneic Stem Cell Transplantation Predict Moderate or Severe Chronic GvHD and Inferior Overall Survival

A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC

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