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Discovery of New Allosteric Modulators of the Urotensinergic System through Substitution of the Urotensin II-Related Peptide (URP) Phenylalanine Residue

Journal of medicinal chemistry, 2018-10, Vol.61 (19), p.8707-8716

2018

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KCTD Proteins Have Redundant Functions in Controlling Cellular Growth

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4993

2024

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The expanding roles of Gβγ subunits in G protein-coupled receptor signaling and drug action

Pharmacological reviews, 2013-04, Vol.65 (2), p.545

2013

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CrossTalk proposal: Weighing the evidence for Class A GPCR dimers, the evidence favours dimers

The Journal of physiology, 2014-06, Vol.592 (12), p.2439-2441

2014

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Conformational Profiling of the AT1 Angiotensin II Receptor Reflects Biased Agonism, G Protein Coupling, and Cellular Context

The Journal of biological chemistry, 2017-03, Vol.292 (13), p.5443-5456

2017

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Urotensin II Receptor Modulation with 1,3,4-Benzotriazepin-2-one Tetrapeptide Mimics

Journal of medicinal chemistry, 2023-10, Vol.66 (20), p.14241-14262

2023

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Therapeutic Targeting of the General RNA Polymerase II Transcription Machinery

International journal of molecular sciences, 2020-05, Vol.21 (9), p.3354

2020

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Shaky ground - The nature of metastable GPCR signalling complexes

Neuropharmacology, 2019-07, Vol.152, p.4-14

2019

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Tools for drug discovery and disease modeling- the future is upon us

Methods (San Diego, Calif.), 2022-07, Vol.203, p.139-141

2022

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G protein-coupled receptor-effector macromolecular membrane assemblies (GEMMAs)

Pharmacology & therapeutics (Oxford), 2022-03, Vol.231, p.107977-107977, Article 107977

2022

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Spt5 C-terminal repeat domain phosphorylation and length negatively regulate heterochromatin through distinct mechanisms

PLoS genetics, 2023-11, Vol.19 (11), p.e1010492-e1010492

2023

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The Dynamics of GPCR Oligomerization and Their Functional Consequences

International review of cell and molecular biology, 2018, Vol.338, p.141

2018

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G protein‐coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function

The Journal of physiology, 2012-03, Vol.590 (6), p.1313-1330

2012

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Design, Synthesis, and Biological Assessment of Biased Allosteric Modulation of the Urotensin II Receptor Using Achiral 1,3,4-Benzotriazepin-2-one Turn Mimics

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9838-9859

2017

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A role for BET proteins in regulating basal, dopamine-induced and cAMP/PKA-dependent transcription in rat striatal neurons

Cellular signalling, 2022-03, Vol.91, p.110226-110226, Article 110226

2022

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G Protein-Biased Agonists for Intracellular Angiotensin Receptors Promote Collagen Secretion in Myofibroblasts

ACS chemical biology, 2023-09, Vol.18 (9), p.2050-2062

2023

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Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody

Nature communications, 2022-08, Vol.13 (1), p.4634-4634, Article 4634

2022

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Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

Scientific reports, 2023-07, Vol.13 (1), p.12248-12248, Article 12248

2023

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Differential Activation of P-TEFb Complexes in the Development of Cardiomyocyte Hypertrophy following Activation of Distinct G Protein-Coupled Receptors

Molecular and cellular biology, 2020-06, Vol.40 (14)

2020

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Evidence for heterodimerization and functional interaction of the urotensin II and the angiotensin II type 1 receptors

Cellular signalling, 2024-04, Vol.116, p.111056-111056, Article 111056

2024

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The Role of Gβγ Subunits in the Organization, Assembly, and Function of GPCR Signaling Complexes

Annual review of pharmacology and toxicology, 2009-02, Vol.49 (1), p.31-56

2009

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Real-time monitoring of receptor and G-protein interactions in living cells

Nature methods, 2005-03, Vol.2 (3), p.177-184

2005

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Editorial: GPCR and G Protein-Mediated Signalling Events in the Nervous System

Frontiers in cellular neuroscience, 2022-05, Vol.16, p.907558-907558

2022

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The Signaling and Pharmacology of the Dopamine D1 Receptor

Frontiers in cellular neuroscience, 2022-01, Vol.15, p.806618-806618

2022

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In vivo detection of GPCR-dependent signaling using fiber photometry and FRET-based biosensors

Methods (San Diego, Calif.), 2022-07, Vol.203, p.422-430

2022

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Discovery of New Allosteric Modulators of the Urotensinergic System through Substitution of the Urotensin II-Related Peptide (URP) Phenylalanine Residue

KCTD Proteins Have Redundant Functions in Controlling Cellular Growth

The expanding roles of Gβγ subunits in G protein-coupled receptor signaling and drug action

CrossTalk proposal: Weighing the evidence for Class A GPCR dimers, the evidence favours dimers

Conformational Profiling of the AT1 Angiotensin II Receptor Reflects Biased Agonism, G Protein Coupling, and Cellular Context

Urotensin II Receptor Modulation with 1,3,4-Benzotriazepin-2-one Tetrapeptide Mimics

Therapeutic Targeting of the General RNA Polymerase II Transcription Machinery

Shaky ground - The nature of metastable GPCR signalling complexes

Tools for drug discovery and disease modeling- the future is upon us

G protein-coupled receptor-effector macromolecular membrane assemblies (GEMMAs)

Spt5 C-terminal repeat domain phosphorylation and length negatively regulate heterochromatin through distinct mechanisms

The Dynamics of GPCR Oligomerization and Their Functional Consequences

G protein‐coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function

Design, Synthesis, and Biological Assessment of Biased Allosteric Modulation of the Urotensin II Receptor Using Achiral 1,3,4-Benzotriazepin-2-one Turn Mimics

A role for BET proteins in regulating basal, dopamine-induced and cAMP/PKA-dependent transcription in rat striatal neurons

G Protein-Biased Agonists for Intracellular Angiotensin Receptors Promote Collagen Secretion in Myofibroblasts

Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody

Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

Differential Activation of P-TEFb Complexes in the Development of Cardiomyocyte Hypertrophy following Activation of Distinct G Protein-Coupled Receptors

Evidence for heterodimerization and functional interaction of the urotensin II and the angiotensin II type 1 receptors

The Role of Gβγ Subunits in the Organization, Assembly, and Function of GPCR Signaling Complexes

Real-time monitoring of receptor and G-protein interactions in living cells

Editorial: GPCR and G Protein-Mediated Signalling Events in the Nervous System

The Signaling and Pharmacology of the Dopamine D1 Receptor

In vivo detection of GPCR-dependent signaling using fiber photometry and FRET-based biosensors

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