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Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41

PloS one, 2013-11, Vol.8 (11), p.e78187

2013

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Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41

PLoS pathogens, 2010-11, Vol.6 (11), p.e1001182

2010

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Peptides from Second Extracellular Loop of C-C Chemokine Receptor Type 5 (CCR5) Inhibit Diverse Strains of HIV-1

The Journal of biological chemistry, 2012-04, Vol.287 (18), p.15076-15086

2012

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Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy

AIDS (London), 1999-12, Vol.13 (17), p.2349-2359

1999

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A Monoclonal Fab Derived from a Human Nonimmune Phage Library Reveals a New Epitope on gp41 and Neutralizes Diverse Human Immunodeficiency Virus Type 1 Strains

Journal of Virology, 2007-12, Vol.81 (23), p.12946-12953

2007

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Synergistic Inhibition of HIV-1 Envelope-Mediated Membrane Fusion by Inhibitors Targeting the N and C-Terminal Heptad Repeats of gp41

Journal of molecular biology, 2006-12, Vol.364 (3), p.283-289

2006

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Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41

Journal of Virology, 2008-10, Vol.82 (20), p.10032-10041

2008

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Solution Structure of the Monovalent Lectin Microvirin in Complex with Manα(1–2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity

The Journal of biological chemistry, 2011-06, Vol.286 (23), p.20788-20796

2011

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Mirabamides A–D, Depsipeptides from the Sponge Siliquariaspongia mirabilis That Inhibit HIV-1 Fusion

Journal of natural products (Washington, D.C.), 2007-11, Vol.70 (11), p.1753-1760

2007

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Complexes of Fabs with a mimetic of the HIV-1 gp41 trimeric coiled-coil

Acta crystallographica. Section A, Foundations and advances, 2014-08, Vol.70 (a1), p.C1809-C1809

2014

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Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth

Virology (New York, N.Y.), 2009-10, Vol.393 (1), p.112-119

2009

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Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36 Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41

Journal of virology, 2008-10, Vol.82 (20), p.10032-10041

2008

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Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41: e1001182

PLoS pathogens, 2010-11, Vol.6 (11)

2010

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Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36Mute,g Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41

Journal of virology, 2008, Vol.82 (20), p.10032-10041

2008

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Characterization and HIV-1 Fusion Inhibitory Properties of Monoclonal Fabs Obtained From a Human Non-immune Phage Library Selected Against Diverse Epitopes of the Ectodomain of HIV-1 gp41

Journal of molecular biology, 2005-11, Vol.353 (5), p.945-951

2005

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Differential Inhibition of HIV-1 and SIV Envelope-Mediated Cell Fusion by C34 Peptides Derived from the C-Terminal Heptad Repeat of gp41 from Diverse Strains of HIV-1, HIV-2, and SIV

Journal of medicinal chemistry, 2005-04, Vol.48 (8), p.3036-3044

2005

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Complexes of Neutralizing and Non-Neutralizing Affinity Matured Fabs with a Mimetic of the Internal Trimeric Coiled-Coil of HIV-1 gp41: e78187

PloS one, 2013-11, Vol.8 (11)

2013

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Drug resistance mutations can affect dimer stability of HIV-1 protease at neutral pH

Protein science, 1999, Vol.8 (8), p.1702-1707

1999

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Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity

The Journal of biological chemistry, 2011-06, Vol.286 (23), p.20788

2011

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Dissection of the pH Dependence of Inhibitor Binding Energetics for an Aspartic Protease: Direct Measurement of the Protonation States of the Catalytic Aspartic Acid Residues

Biochemistry (Easton), 1997-12, Vol.36 (51), p.16166-16172

1997

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Design and characterization of HIV fusion inhibitors targeting gp41

Gustchina, Elena

2006

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Limulus Ancient Innate Responses

Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems, 2019, p.631-682

2019

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Post X-ray crystallographic studies of chymosin: the existence of two structural forms and the regulation of activity by the interaction with the histidine-proline cluster of κ-casein

FEBS letters, 1996-01, Vol.379 (1), p.60-62

1996

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Utility of (His)6 Tag for Purification and Refolding of Proplasmepsin-2 and Mutants with Altered Activation Properties

Protein expression and purification, 2002-04, Vol.24 (3), p.412-419

2002

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A novel putative transcription factor protein MYT2 that preferentially binds supercoiled DNA and induces DNA synthesis in quiescent cells

FEBS letters, 2000-05, Vol.473 (3), p.363-369

2000

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Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41

Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41

Peptides from Second Extracellular Loop of C-C Chemokine Receptor Type 5 (CCR5) Inhibit Diverse Strains of HIV-1

Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy

A Monoclonal Fab Derived from a Human Nonimmune Phage Library Reveals a New Epitope on gp41 and Neutralizes Diverse Human Immunodeficiency Virus Type 1 Strains

Synergistic Inhibition of HIV-1 Envelope-Mediated Membrane Fusion by Inhibitors Targeting the N and C-Terminal Heptad Repeats of gp41

Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41

Solution Structure of the Monovalent Lectin Microvirin in Complex with Manα(1–2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity

Mirabamides A–D, Depsipeptides from the Sponge Siliquariaspongia mirabilis That Inhibit HIV-1 Fusion

Complexes of Fabs with a mimetic of the HIV-1 gp41 trimeric coiled-coil

Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth

Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36 Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41

Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41: e1001182

Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36Mute,g Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41

Characterization and HIV-1 Fusion Inhibitory Properties of Monoclonal Fabs Obtained From a Human Non-immune Phage Library Selected Against Diverse Epitopes of the Ectodomain of HIV-1 gp41

Differential Inhibition of HIV-1 and SIV Envelope-Mediated Cell Fusion by C34 Peptides Derived from the C-Terminal Heptad Repeat of gp41 from Diverse Strains of HIV-1, HIV-2, and SIV

Complexes of Neutralizing and Non-Neutralizing Affinity Matured Fabs with a Mimetic of the Internal Trimeric Coiled-Coil of HIV-1 gp41: e78187

Drug resistance mutations can affect dimer stability of HIV-1 protease at neutral pH

Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity

Dissection of the pH Dependence of Inhibitor Binding Energetics for an Aspartic Protease: Direct Measurement of the Protonation States of the Catalytic Aspartic Acid Residues

Design and characterization of HIV fusion inhibitors targeting gp41

Limulus Ancient Innate Responses

Post X-ray crystallographic studies of chymosin: the existence of two structural forms and the regulation of activity by the interaction with the histidine-proline cluster of κ-casein

Utility of (His)6 Tag for Purification and Refolding of Proplasmepsin-2 and Mutants with Altered Activation Properties

A novel putative transcription factor protein MYT2 that preferentially binds supercoiled DNA and induces DNA synthesis in quiescent cells

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