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Cytokines in CAR T Cell-Associated Neurotoxicity

Frontiers in immunology, 2020-12, Vol.11, p.577027

2020

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Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis

Nature medicine, 2021-09, Vol.27 (9), p.1544-1552

2021

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Transplantation of Human Embryonic Stem Cell-Derived Photoreceptors Restores Some Visual Function in Crx-Deficient Mice

Cell stem cell, 2009-01, Vol.4 (1), p.73-79

2009

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BCMA-CAR T-cell treatment-associated parkinsonism

Blood, 2023-10, Vol.142 (14), p.1181

Gust, Juliane

2023

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Beyond the storm - subacute toxicities and late effects in children receiving CAR T cells

Nature reviews. Clinical oncology, 2021-06, Vol.18 (6), p.363-378

2021

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Immunotherapy Associated Neurotoxicity in Pediatric Oncology

Frontiers in oncology, 2022-02, Vol.12, p.836452

2022

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Locoregional CAR T cells for children with CNS tumors: Clinical procedure and catheter safety

Neoplasia (New York, N.Y.), 2023-02, Vol.36, p.100870-100870, Article 100870

2023

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Characterization of a severe case of PIK3CA‐related overgrowth at autopsy by droplet digital polymerase chain reaction and report of PIK3CA sequencing in 22 patients

American journal of medical genetics. Part A, 2018-11, Vol.176 (11), p.2301-2308

2018

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Pediatric ependymoma: New perspectives on older trials

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (6), p.949-950

2022

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Neurotoxicity Associated with CD19-Targeted CAR-T Cell Therapies

CNS drugs, 2018-12, Vol.32 (12), p.1091-1101

2018

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How I treat unique and difficult-to-manage cases of CAR T-cell therapy–associated neurotoxicity

Blood, 2023-05, Vol.141 (20), p.2443-2451

2023

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How Cancer Harms the Developing Brain: Long-Term Outcomes in Pediatric Cancer Survivors

Pediatric neurology, 2024-07, Vol.156, p.91-98

2024

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Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy

Blood, 2017-11, Vol.130 (21), p.2295-2306

2017

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Preemptive mitigation of CD19 CAR T-cell cytokine release syndrome without attenuation of antileukemic efficacy

Blood, 2019-12, Vol.134 (24), p.2149-2158

2019

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Adult donor rod photoreceptors integrate into the mature mouse retina

Investigative ophthalmology & visual science, 2011-07, Vol.52 (8), p.5266-5272

2011

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Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells

Cancer discovery, 2017-12, Vol.7 (12), p.1404-1419

2017

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EEG Correlates of Delirium in Children and Young Adults With CD19-Directed CAR T Cell Treatment-Related Neurotoxicity

Journal of clinical neurophysiology, 2021-03, Vol.38 (2), p.135

2021

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Glial injury in neurotoxicity after pediatric CD19‐directed chimeric antigen receptor T cell therapy

Annals of neurology, 2019-07, Vol.86 (1), p.42-54

2019

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TRLS-12. INTRAVENTRICULAR B7-H3 CAR T CELLS FOR DIFFUSE INTRINSIC PONTINE GLIOMA: INTERIM ANALYSIS OF BRAINCHILD-03 ARM C

Neuro-oncology (Charlottesville, Va.), 2023-06, Vol.25 (Supplement_1), p.i81-i82

2023

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LTBK-03. Targeted mass spectrometry of serial CSF and serum specimens from children with diffuse intrinsic pontine glioma treated with intracranial B7-H3 CAR T cells

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i191-i191

2022

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Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety

Cancer discovery, 2023-01, Vol.13 (1), p.114-131, Article 114

2023

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Tumor inflammation-associated neurotoxicity

Nature medicine, 2023-04, Vol.29 (4), p.803-810

2023

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TRLS-01. INTRAVENTRICULAR B7-H3 CAR T CELLS FOR DIFFUSE INTRINSIC PONTINE GLIOMA: SAFETY AND EFFICACY REPORT FROM THE COMPLETED PHASE 1 TRIAL BRAINCHILD-03

Neuro-oncology (Charlottesville, Va.), 2024-06, Vol.26 (Supplement_4), p.0-0

2024

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EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma

Oncotarget, 2019-12, Vol.10 (66), p.7080-7095

2019

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Neuro-Oncology Training for the Child Neurology Resident

Journal of Child Neurology, 2021-01, Vol.36 (1), p.79-82

2021

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Cytokines in CAR T Cell-Associated Neurotoxicity

Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis

Transplantation of Human Embryonic Stem Cell-Derived Photoreceptors Restores Some Visual Function in Crx-Deficient Mice

BCMA-CAR T-cell treatment-associated parkinsonism

Beyond the storm - subacute toxicities and late effects in children receiving CAR T cells

Immunotherapy Associated Neurotoxicity in Pediatric Oncology

Locoregional CAR T cells for children with CNS tumors: Clinical procedure and catheter safety

Characterization of a severe case of PIK3CA‐related overgrowth at autopsy by droplet digital polymerase chain reaction and report of PIK3CA sequencing in 22 patients

Pediatric ependymoma: New perspectives on older trials

Neurotoxicity Associated with CD19-Targeted CAR-T Cell Therapies

How I treat unique and difficult-to-manage cases of CAR T-cell therapy–associated neurotoxicity

How Cancer Harms the Developing Brain: Long-Term Outcomes in Pediatric Cancer Survivors

Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy

Preemptive mitigation of CD19 CAR T-cell cytokine release syndrome without attenuation of antileukemic efficacy

Adult donor rod photoreceptors integrate into the mature mouse retina

Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells

EEG Correlates of Delirium in Children and Young Adults With CD19-Directed CAR T Cell Treatment-Related Neurotoxicity

Glial injury in neurotoxicity after pediatric CD19‐directed chimeric antigen receptor T cell therapy

TRLS-12. INTRAVENTRICULAR B7-H3 CAR T CELLS FOR DIFFUSE INTRINSIC PONTINE GLIOMA: INTERIM ANALYSIS OF BRAINCHILD-03 ARM C

LTBK-03. Targeted mass spectrometry of serial CSF and serum specimens from children with diffuse intrinsic pontine glioma treated with intracranial B7-H3 CAR T cells

Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety

Tumor inflammation-associated neurotoxicity

TRLS-01. INTRAVENTRICULAR B7-H3 CAR T CELLS FOR DIFFUSE INTRINSIC PONTINE GLIOMA: SAFETY AND EFFICACY REPORT FROM THE COMPLETED PHASE 1 TRIAL BRAINCHILD-03

EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma

Neuro-Oncology Training for the Child Neurology Resident

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