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The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

Nature (London), 2012-02, Vol.482 (7386), p.542-546

2012

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Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

Cancer cell, 2010-10, Vol.18 (4), p.329-340

2010

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Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20358-20363

2010

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Stigmatellin Induces Reduction of Iron-Sulfur Protein in the Oxidized Cytochrome bc1 Complex

The Journal of biological chemistry, 2008-10, Vol.283 (42), p.28087-28094

2008

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Bispecific and split CAR T cells targeting CD13 and TIM3 eradicate acute myeloid leukemia

Blood, 2020-03, Vol.135 (10), p.713-723

2020

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Menin directly represses Gli1 expression independent of canonical Hedgehog signaling

Molecular cancer research, 2013-10, Vol.11 (10), p.1215-1222

2013

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Menin Is Required for Optimal Processing of the MicroRNA let-7a

The Journal of biological chemistry, 2014-04, Vol.289 (14), p.9902-9908

2014

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The Iron-Sulfur Cluster of the Rieske Iron-Sulfur Protein Functions as a Proton-exiting Gate in the Cytochrome bc1 Complex

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.24895-24902

2005

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Menin/PRMT5/hedgehog signaling: a potential target for the treatment of multiple endocrine neoplasia type 1 tumors

Epigenomics, 2013-10, Vol.5 (5), p.469-471

2013

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An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis

Cancer cell, 2015-10, Vol.28 (4), p.472-485

2015

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Development of Multi-Engineered iPSC-Derived CAR-NK Cells for the Treatment of B-Cell Malignancies

Blood, 2021-11, Vol.138 (Supplement 1), p.1729-1729

2021

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Abstract 2914: iPSC-derived CAR-NK cell therapy: nominating clinical candidate clones through integrated multi-functional analysis

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2914-2914

2023

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Menin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8), p.2650-2658

2013

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Islet-specific Prmt5 excision leads to reduced insulin expression and glucose intolerance in mice

Journal of endocrinology, 2020-01, Vol.244 (1), p.41-52

2020

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Menin Directly Represses Expression of Gli1 Independent of the Canonical Hedgehog Signaling Pathway

Molecular cancer research, 2013-08, Vol.11 (10), p.1215-1222

2013

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Menin/PRMT5/Hedgehog signaling: A Potential Target for the Treatment of MEN1 Tumors

Epigenomics, 2013-01, Vol.5 (5), p.469-471

2013

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Abstract 36: The discovery of a novel CD19xCD22 dual-targeting CAR for the development of an IPSC-derived cell therapy

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.36-36

2024

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Abstract 1320: Engineered expression of HLA-E and HLA-G protects iPSC-derived cells from killing by primary NK cells

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1320-1320

2024

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Abstract 1916: Discovery of a novel Nectin4 IPSC-derived cell therapy for the treatment of solid tumors

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1916-1916

2024

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Abstract 6802: CXCR4 transgene improves in vivo migration and efficacy of engineered iPSC-derived natural killer cells

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.6802-6802

2024

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PTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target

Cancer biology & therapy, 2015-02, Vol.16 (2), p.219-224

2015

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Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells

Oncoscience, 2014, Vol.1 (9), p.562-566

2014

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265 Empowering iPSC-derived iNK cells with multiple gene edits to improve persistence and anti-tumor efficacy

Journal for immunotherapy of cancer, 2022-11, Vol.10 (Suppl 2), p.A280-A280

2022

Volltextzugriff (PDF)

The same pocket in menin binds both MLL and JunD, but oppositely regulates transcription

Nature (London), 2012-02, Vol.482 (7386), p.542-546

2012

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SUMO modification of menin

American journal of cancer research, 2013-01, Vol.3 (1), p.96-106

2013

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The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene

Stigmatellin Induces Reduction of Iron-Sulfur Protein in the Oxidized Cytochrome bc1 Complex

Bispecific and split CAR T cells targeting CD13 and TIM3 eradicate acute myeloid leukemia

Menin directly represses Gli1 expression independent of canonical Hedgehog signaling

Menin Is Required for Optimal Processing of the MicroRNA let-7a

The Iron-Sulfur Cluster of the Rieske Iron-Sulfur Protein Functions as a Proton-exiting Gate in the Cytochrome bc1 Complex

Menin/PRMT5/hedgehog signaling: a potential target for the treatment of multiple endocrine neoplasia type 1 tumors

An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis

Development of Multi-Engineered iPSC-Derived CAR-NK Cells for the Treatment of B-Cell Malignancies

Abstract 2914: iPSC-derived CAR-NK cell therapy: nominating clinical candidate clones through integrated multi-functional analysis

Menin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome

Islet-specific Prmt5 excision leads to reduced insulin expression and glucose intolerance in mice

Menin Directly Represses Expression of Gli1 Independent of the Canonical Hedgehog Signaling Pathway

Menin/PRMT5/Hedgehog signaling: A Potential Target for the Treatment of MEN1 Tumors

Abstract 36: The discovery of a novel CD19xCD22 dual-targeting CAR for the development of an IPSC-derived cell therapy

Abstract 1320: Engineered expression of HLA-E and HLA-G protects iPSC-derived cells from killing by primary NK cells

Abstract 1916: Discovery of a novel Nectin4 IPSC-derived cell therapy for the treatment of solid tumors

Abstract 6802: CXCR4 transgene improves in vivo migration and efficacy of engineered iPSC-derived natural killer cells

PTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target

Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells

265 Empowering iPSC-derived iNK cells with multiple gene edits to improve persistence and anti-tumor efficacy

The same pocket in menin binds both MLL and JunD, but oppositely regulates transcription

SUMO modification of menin

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