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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase

Cancer cell, 2017-01, Vol.31 (1), p.127-141

2017

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Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS

Blood, 2018-06, Vol.131 (24), p.2682-2697

2018

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SETBP1 sets the stage

Blood, 2024-04, Vol.143 (14), p.1323-1324

Gurbuxani, Sandeep

2024

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Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome

The Journal of clinical investigation, 2012-03, Vol.122 (3), p.948-962

2012

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Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition

Nature medicine, 2015-12, Vol.21 (12), p.1473-1480

2015

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miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia

Nature communications, 2016-04, Vol.7 (1), p.11452-11452, Article 11452

2016

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TET1 plays an essential oncogenic role in MLL-rearranged leukemia

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (29), p.11994-11999

2013

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Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms

Blood, 2021-09, Vol.138 (9), p.790-805

2021

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CXCL4's “Gliful” subversion of BM in MPN

Blood, 2020-10, Vol.136 (18), p.1999-2000

Gurbuxani, Sandeep

2020

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LKB1/ STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms

Cancer discovery, 2021-06, Vol.11 (6), p.1398-1410

2021

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Blockade of miR-150 Maturation by MLL-Fusion/MYC/LIN-28 Is Required for MLL-Associated Leukemia

Cancer cell, 2012-10, Vol.22 (4), p.524-535

2012

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Overexpression and knockout of miR-126 both promote leukemogenesis

Blood, 2015-10, Vol.126 (17), p.2005-2015

2015

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Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks

Clinical cancer research, 2019-09, Vol.25 (18), p.5638-5649

2019

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PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (3), p.619-629

2016

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miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia–rearranged leukemia

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (28), p.11511-11516

2013

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miR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (47), p.19397-19402

2012

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Clinical and molecular response of acute myeloid leukemia harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors

Haematologica (Roma), 2023-08, Vol.108 (8), p.2234-2239

2023

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Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis

PloS one, 2016-09, Vol.11 (9), p.e0162515-e0162515

2016

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Lymphoblastic leukemia following MDS or MDS/MPN: clinical evidence for stem cell origins of these disorders

Leukemia & lymphoma, 2019-10, Vol.60 (12), p.2847-2848

Gurbuxani, Sandeep

2019

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HSP27 Is a Ubiquitin-Binding Protein Involved in I-κBα Proteasomal Degradation

Molecular and Cellular Biology, 2003-08, Vol.23 (16), p.5790-5802

2003

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Heat-shock protein 70 antagonizes apoptosis-inducing factor

Nature cell biology, 2001-09, Vol.3 (9), p.839-843

2001

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Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor

Oncogene, 2003-10, Vol.22 (43), p.6669-6678

2003

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Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

Blood, 2008-01, Vol.111 (2), p.767-775

2008

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Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells

The Journal of experimental medicine, 2007-07, Vol.204 (7), p.1603-1611

2007

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Red cell morphology in sickle cell disease

Blood, 2020-10, Vol.136 (16), p.1893-1893

2020

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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase

Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS

SETBP1 sets the stage

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome

Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition

miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia

TET1 plays an essential oncogenic role in MLL-rearranged leukemia

Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms

CXCL4's “Gliful” subversion of BM in MPN

LKB1/ STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms

Blockade of miR-150 Maturation by MLL-Fusion/MYC/LIN-28 Is Required for MLL-Associated Leukemia

Overexpression and knockout of miR-126 both promote leukemogenesis

Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks

PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease

miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia–rearranged leukemia

miR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia

Clinical and molecular response of acute myeloid leukemia harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors

Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis

Lymphoblastic leukemia following MDS or MDS/MPN: clinical evidence for stem cell origins of these disorders

HSP27 Is a Ubiquitin-Binding Protein Involved in I-κBα Proteasomal Degradation

Heat-shock protein 70 antagonizes apoptosis-inducing factor

Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor

Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells

Red cell morphology in sickle cell disease

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