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Effectiveness and Tolerability of Colesevelam HCl for Accelerated Elimination of Teriflunomide in Healthy Participants

Journal of clinical pharmacology, 2017-06, Vol.57 (6), p.747-750

2017

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Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate

Carcinogenesis (New York), 1996-04, Vol.17 (4), p.809-813

1996

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Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes

Drug metabolism and disposition, 1997-03, Vol.25 (3), p.390

1997

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Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats

Carcinogenesis (New York), 1992-12, Vol.13 (12), p.2205-2210

1992

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Effect of deuteration on metabolism and clearance of Nerispirdine (HP184) and AVE5638

Bioorganic & medicinal chemistry, 2015-07, Vol.23 (13), p.3831-3842

2015

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Comparative in vitro metabolism of 14C-ciclesonide in hepatocytes from the mouse, rat, rabbit, dog, and human

American journal of therapeutics, 2007-05, Vol.14 (3), p.280

2007

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Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice

Carcinogenesis (New York), 1993-06, Vol.14 (6), p.1167-1173

1993

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[4] Purification of functional recombinant P450s from bacteria

Methods in Enzymology, 1996, Vol.272, p.35-44

1996

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Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate

Cancer research (Chicago, Ill.), 1993-07, Vol.53 (14), p.3276-3282

1993

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Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates

Cancer research (Chicago, Ill.), 1990-11, Vol.50 (21), p.6817-6822

1990

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Comparison of CYP3A activities in a subclone of caco-2 cells (TC7) and human intestine

Pharmaceutical research, 1997-08, Vol.14 (8), p.1019-1025

1997

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Bioactivation of aromatic amines by recombinant human cytochrome P4501A2 expressed in Ames tester strain bacteria : a substitute for activation by mammalian tissue preparations

Cancer research (Chicago, Ill.), 1995-02, Vol.55 (4), p.799-802

1995

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Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats

Archives of biochemistry and biophysics, 1992-10, Vol.298 (1), p.279-286

1992

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Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa

Carcinogenesis (New York), 1992-08, Vol.13 (8), p.1409-1414

1992

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Protein binding and its potential for eliciting minimal systemic side effects with a novel inhaled corticosteroid, ciclesonide

American journal of therapeutics, 2005-05, Vol.12 (3), p.201

2005

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Estimation of Oral Bioavailability in the Rat by the Accelerated Infusion Technique

Journal of pharmacy and pharmacology, 2000-08, Vol.52 (8), p.957-961

2000

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Oxidation of Benzo[a]pyrene by Recombinant Human Cytochrome P450 Enzymes

Chemical research in toxicology, 1995-01, Vol.8 (1), p.136-142

1995

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Expression of Modified Human Cytochrome P450 1A2 in Escherichia coli: Stabilization, Purification, Spectral Characterization, and Catalytic Activities of the Enzyme

Archives of biochemistry and biophysics, 1994-02, Vol.309 (1), p.168-177

1994

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Expression of Modified Human Cytochrome P450 2E1 in Escherichia coli, Purification, and Spectral and Catalytic Properties

Archives of biochemistry and biophysics, 1994-07, Vol.312 (1), p.59-66

1994

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Ciclesonide disposition and metabolism: pharmacokinetics, metabolism, and excretion in the mouse, rat, rabbit, and dog

American journal of therapeutics, 2006-11, Vol.13 (6), p.490

2006

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Expression of Cytochrome-P450-3A5 in Escherichia Coli: Effects of 5′ Modification, Purification, Spectral Characterization, Reconstitution Conditions, and Catalytic Activities

Archives of biochemistry and biophysics, 1995-03, Vol.317 (2), p.374-384

1995

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Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation

Drug metabolism and disposition, 1995-03, Vol.23 (3), p.438

1995

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Expression of Cytochrome P450 2D6 in Escherichia coli, Purification, and Spectral and Catalytic Characterization

Archives of biochemistry and biophysics, 1995-06, Vol.319 (2), p.540-550

1995

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Aryl Acetylenes as Mechanism-Based Inhibitors of Cytochrome P450-Dependent Monooxygenase Enzymes

Chemical research in toxicology, 1997-01, Vol.10 (1), p.91-102

1997

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Expression of Modified Human Cytochrome P450 1A1 in Escherichia coli: Effects of 5′ Substitution, Stabilization, Purification, Spectral Characterization, and Catalytic Properties

Archives of biochemistry and biophysics, 1994-08, Vol.312 (2), p.436-446

1994

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Effectiveness and Tolerability of Colesevelam HCl for Accelerated Elimination of Teriflunomide in Healthy Participants

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate

Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes

Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats

Effect of deuteration on metabolism and clearance of Nerispirdine (HP184) and AVE5638

Comparative in vitro metabolism of 14C-ciclesonide in hepatocytes from the mouse, rat, rabbit, dog, and human

Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice

[4] Purification of functional recombinant P450s from bacteria

Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates

Comparison of CYP3A activities in a subclone of caco-2 cells (TC7) and human intestine

Bioactivation of aromatic amines by recombinant human cytochrome P4501A2 expressed in Ames tester strain bacteria : a substitute for activation by mammalian tissue preparations

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats

Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa

Protein binding and its potential for eliciting minimal systemic side effects with a novel inhaled corticosteroid, ciclesonide

Estimation of Oral Bioavailability in the Rat by the Accelerated Infusion Technique

Oxidation of Benzo[a]pyrene by Recombinant Human Cytochrome P450 Enzymes

Expression of Modified Human Cytochrome P450 1A2 in Escherichia coli: Stabilization, Purification, Spectral Characterization, and Catalytic Activities of the Enzyme

Expression of Modified Human Cytochrome P450 2E1 in Escherichia coli, Purification, and Spectral and Catalytic Properties

Ciclesonide disposition and metabolism: pharmacokinetics, metabolism, and excretion in the mouse, rat, rabbit, and dog

Expression of Cytochrome-P450-3A5 in Escherichia Coli: Effects of 5′ Modification, Purification, Spectral Characterization, Reconstitution Conditions, and Catalytic Activities

Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation

Expression of Cytochrome P450 2D6 in Escherichia coli, Purification, and Spectral and Catalytic Characterization

Aryl Acetylenes as Mechanism-Based Inhibitors of Cytochrome P450-Dependent Monooxygenase Enzymes

Expression of Modified Human Cytochrome P450 1A1 in Escherichia coli: Effects of 5′ Substitution, Stabilization, Purification, Spectral Characterization, and Catalytic Properties

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