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Drug targets in the cytokine universe for autoimmune disease

Trends in immunology, 2013-03, Vol.34 (3), p.120-128

2013

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Association of CD4+CD25+Foxp3+ regulatory T cells with chronic activity and viral clearance in patients with hepatitis B

International immunology, 2007-02, Vol.19 (2), p.133-140

2007

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Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

Nature medicine, 2013-03, Vol.19 (3), p.322-328

2013

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Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer

Cancer letters, 2007-08, Vol.253 (1), p.34-42

2007

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Promoting remyelination for the treatment of multiple sclerosis： opportunities and challenges

Neuroscience bulletin, 2013-04, Vol.29 (2), p.144-154

2013

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Discovery of Novel 1,2,4-Thiadiazole Derivatives as Potent, Orally Active Agonists of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1)

Journal of medicinal chemistry, 2012-05, Vol.55 (9), p.4286-4296

2012

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Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease

Nature medicine, 2010-02, Vol.16 (2), p.191-197

2010

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Thymic Regulation of Autoimmune Disease by Accelerated Differentiation of Foxp3+ Regulatory T Cells through IL-7 Signaling Pathway

The Journal of immunology (1950), 2009-11, Vol.183 (10), p.6135-6144

2009

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1364 Discovery of NXA01, a novel CD24 antibody with tumor selectivity and potent anti-tumor activity

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1520-A1520

2023

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Anti-Inflammatory Properties and Regulatory Mechanism of a Novel Derivative of Artemisinin in Experimental Autoimmune Encephalomyelitis

The Journal of immunology (1950), 2007-11, Vol.179 (9), p.5958-5965

2007

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Angiogenesis by transplantation of HIF-1α modified EPCs into ischemic limbs

Journal of cellular biochemistry, 2008-01, Vol.103 (1), p.321-334

2008

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Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis

The Journal of immunology (1950), 2008-07, Vol.181 (2), p.1491-1498

2008

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Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (21), p.6349-6358

2013

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K+ channel activity and redox status are differentially required for JNK activation by UV and reactive oxygen species

Experimental cell research, 2004-07, Vol.297 (2), p.461-471

2004

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High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response

Cell research, 2010-04, Vol.20 (4), p.480-491

2010

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Identification of benzoxazole analogs as novel, S1P(3) sparing S1P(1) agonists

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.3973-3977

2012

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Identification of benzoxazole analogs as novel, S1P3 sparing S1P1 agonists

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.3973-3977

2012

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Discovery of thiadiazole amides as potent, S1P3-sparing agonists of sphingosine-1-phosphate 1 (S1P1) receptor

Bioorganic & medicinal chemistry letters, 2012-04, Vol.22 (7), p.2456-2459

2012

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Inhibition of Hypoxia-Inducible Factor-1[alpha] and Endothelial Progenitor Cell Differentiation by Adenoviral Transfer of Small Interfering RNA in vitro

Journal of vascular research, 2006-11, Vol.43 (6), p.511

2006

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Abstract 1871: A differentiated CD73 blocking antibody with a unique intra-dimer binding mechanism for cancer immunotherapy

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1871-1871

2021

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Indole-propionic acid derivatives as potent, S1P3-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P1) receptor agonists

Bioorganic & medicinal chemistry letters, 2012-04, Vol.22 (8), p.2794-2797

2012

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Discovery of BCL-XL Heterobifunctional Degrader with Potentially Improved Therapeutic Window and Minimal Platelet Toxicity for Hematological Malignancies

Blood, 2023-11, Vol.142 (Supplement 1), p.117-117

2023

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Abstract 5644: Claudin 18.2 X 4-1BB bispecific antibody induced potent tumor inhibition through tumor-specific 4-1BB activation

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5644-5644

2020

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Inhibition of Hypoxia-Inducible Factor-1α and Endothelial Progenitor Cell Differentiation by Adenoviral Transfer of Small Interfering RNA in vitro

Journal of vascular research, 2006-11, Vol.43 (6), p.511-521

2006

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Inhibitory effect of PPAR on the expression of EMMPRIN in macrophages and foam cells

International journal of cardiology, 2007-05, Vol.117 (3), p.373-380

2007

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Drug targets in the cytokine universe for autoimmune disease

Association of CD4+CD25+Foxp3+ regulatory T cells with chronic activity and viral clearance in patients with hepatitis B

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer

Promoting remyelination for the treatment of multiple sclerosis： opportunities and challenges

Discovery of Novel 1,2,4-Thiadiazole Derivatives as Potent, Orally Active Agonists of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1)

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease

Thymic Regulation of Autoimmune Disease by Accelerated Differentiation of Foxp3+ Regulatory T Cells through IL-7 Signaling Pathway

1364 Discovery of NXA01, a novel CD24 antibody with tumor selectivity and potent anti-tumor activity

Anti-Inflammatory Properties and Regulatory Mechanism of a Novel Derivative of Artemisinin in Experimental Autoimmune Encephalomyelitis

Angiogenesis by transplantation of HIF-1α modified EPCs into ischemic limbs

Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis

Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors

K+ channel activity and redox status are differentially required for JNK activation by UV and reactive oxygen species

High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response

Identification of benzoxazole analogs as novel, S1P(3) sparing S1P(1) agonists

Identification of benzoxazole analogs as novel, S1P3 sparing S1P1 agonists

Discovery of thiadiazole amides as potent, S1P3-sparing agonists of sphingosine-1-phosphate 1 (S1P1) receptor

Inhibition of Hypoxia-Inducible Factor-1[alpha] and Endothelial Progenitor Cell Differentiation by Adenoviral Transfer of Small Interfering RNA in vitro

Abstract 1871: A differentiated CD73 blocking antibody with a unique intra-dimer binding mechanism for cancer immunotherapy

Indole-propionic acid derivatives as potent, S1P3-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P1) receptor agonists

Discovery of BCL-XL Heterobifunctional Degrader with Potentially Improved Therapeutic Window and Minimal Platelet Toxicity for Hematological Malignancies

Abstract 5644: Claudin 18.2 X 4-1BB bispecific antibody induced potent tumor inhibition through tumor-specific 4-1BB activation

Inhibition of Hypoxia-Inducible Factor-1α and Endothelial Progenitor Cell Differentiation by Adenoviral Transfer of Small Interfering RNA in vitro

Inhibitory effect of PPAR on the expression of EMMPRIN in macrophages and foam cells

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