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Glucose feeds the TCA cycle via circulating lactate

Nature (London), 2017-11, Vol.551 (7678), p.115-118

2017

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Autophagy-Mediated Tumor Promotion

Cell, 2013-12, Vol.155 (6), p.1216-1219

2013

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Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration

PLoS genetics, 2022-04, Vol.18 (4), p.e1010138-e1010138

2022

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Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRASG12D-driven lung tumors

Autophagy, 2013-10, Vol.9 (10), p.1636-1638

2013

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Autophagy maintains tumour growth through circulating arginine

Nature (London), 2018-11, Vol.563 (7732), p.569-573

2018

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Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells

Genes & development, 2016-08, Vol.30 (15), p.1704-1717

2016

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Autophagy is required for glucose homeostasis and lung tumor maintenance

Cancer discovery, 2014-08, Vol.4 (8), p.914-927

2014

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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

Genes & development, 2011-03, Vol.25 (5), p.460-470

2011

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Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

Genes & development, 2013-07, Vol.27 (13), p.1447-1461

2013

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CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

Cell reports (Cambridge), 2019-12, Vol.29 (11), p.3405-3420.e5

2019

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Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism

Cell reports (Cambridge), 2019-10, Vol.29 (5), p.1287-1298.e6

2019

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Ym155 localizes to the mitochondria leading to mitochondria dysfunction and activation of AMPK that inhibits BMP signaling in lung cancer cells

Scientific reports, 2022-07, Vol.12 (1), p.13135-13135, Article 13135

2022

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Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1

The Journal of clinical investigation, 2022-12, Vol.132 (24), p.1-18

2022

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Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer

Nature communications, 2024-07, Vol.15 (1), p.5857-18, Article 5857

2024

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Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival

eLife, 2020-11, Vol.9

2020

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PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation

Nature cell biology, 2009-05, Vol.11 (5), p.644-651

2009

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Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors

Cell death & disease, 2023-01, Vol.14 (1), p.61-61, Article 61

2023

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Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes

Frontiers in immunology, 2021-10, Vol.12, p.670338-670338

2021

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Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesis

Cell death & disease, 2022-04, Vol.13 (4), p.370-12, Article 370

2022

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Autophagy, Metabolism, and Cancer

Cold Spring Harbor Symposia on Quantitative Biology, 2016, Vol.81, p.73-78

2016

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Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRAS(G12D)-driven lung tumors

Autophagy, 2013-10, Vol.9 (10), p.1636

2013

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Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer

Clinical and translational medicine, 2023-06, Vol.13 (6), p.e1298-n/a

2023

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Transient systemic autophagy ablation irreversibly inhibits lung tumor cell metabolism and promotes T-cell mediated tumor killing

Autophagy, 2023-06, Vol.19 (6), p.1879-1881

2023

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Impaired Autophagy and Defective T Cell Homeostasis in Mice with T Cell-Specific Deletion of Receptor for Activated C Kinase 1

Frontiers in immunology, 2017-05, Vol.8, p.575-575

2017

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Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1 -deficient Kras -driven lung tumorigenesis

Genes & development, 2019-02, Vol.33 (3-4), p.150-165

2019

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Glucose feeds the TCA cycle via circulating lactate

Autophagy-Mediated Tumor Promotion

Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration

Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRASG12D-driven lung tumors

Autophagy maintains tumour growth through circulating arginine

Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells

Autophagy is required for glucose homeostasis and lung tumor maintenance

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism

Ym155 localizes to the mitochondria leading to mitochondria dysfunction and activation of AMPK that inhibits BMP signaling in lung cancer cells

Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1

Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer

Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival

PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation

Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors

Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes

Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesis

Autophagy, Metabolism, and Cancer

Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRAS(G12D)-driven lung tumors

Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer

Transient systemic autophagy ablation irreversibly inhibits lung tumor cell metabolism and promotes T-cell mediated tumor killing

Impaired Autophagy and Defective T Cell Homeostasis in Mice with T Cell-Specific Deletion of Receptor for Activated C Kinase 1

Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1 -deficient Kras -driven lung tumorigenesis

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