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CYP4F2-Catalyzed Metabolism of Arachidonic Acid Promotes Stromal Cell-Mediated Immunosuppression in Non–Small Cell Lung Cancer

Cancer research (Chicago, Ill.), 2022-11, Vol.82 (21), p.4016-4030

2022

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20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis

Journal of cerebral blood flow and metabolism, 2019-08, Vol.39 (8), p.1531-1543

2019

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Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6

Toxicology and applied pharmacology, 2014-09, Vol.279 (3), p.311-321

2014

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Neutrophil-Derived Myeloperoxidase and Hypochlorous Acid Critically Contribute to 20-Hydroxyeicosatetraenoic Acid Increases that Drive Postischemic Angiogenesis

The Journal of pharmacology and experimental therapeutics, 2022-06, Vol.381 (3), p.204

2022

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ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma

Oncogene, 2021-10, Vol.40 (40), p.5925-5937

2021

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Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion

Toxicology and applied pharmacology, 2014-10, Vol.280 (1), p.10-20

2014

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CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells

American journal of physiology. Heart and circulatory physiology, 2019-06, Vol.316 (6), p.H1468-H1479

2019

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HET0016, a selective inhibitor of 20-HETE synthesis, decreases pro-angiogenic factors and inhibits growth of triple negative breast cancer in mice

PloS one, 2014-12, Vol.9 (12), p.e116247

2014

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20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo

The Journal of pharmacology and experimental therapeutics, 2014-03, Vol.348 (3), p.442

2014

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Human cord blood-derived AC133+ progenitor cells preserve endothelial progenitor characteristics after long term in vitro expansion

PloS one, 2010-02, Vol.5 (2), p.e9173-e9173

2010

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Eicosanoids: Emerging contributors in stem cell-mediated wound healing

Prostaglandins & other lipid mediators, 2017-09, Vol.132, p.17-24

2017

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20-HETE in neovascularization

Prostaglandins & other lipid mediators, 2012-08, Vol.98 (3-4), p.63-68

2012

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Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer

Toxicology and applied pharmacology, 2013-10, Vol.272 (1), p.37-48

2013

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Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid

Frontiers in pharmacology, 2023-01, Vol.13, p.1042756-1042756

2023

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Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer

Cancer chemotherapy and pharmacology, 2011-09, Vol.68 (3), p.619-629

2011

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Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation

The Journal of pharmacology and experimental therapeutics, 2007-04, Vol.321 (1), p.18

2007

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Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma

OncoTargets and therapy, 2016-01, Vol.9 (Issue 1), p.1205-1219

2016

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Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis

American journal of physiology. Regulatory, integrative and comparative physiology, 2007-10, Vol.293 (4), p.R1619-R1629

2007

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20-HETE contributes to ischemia-induced angiogenesis

Vascular pharmacology, 2016-08, Vol.83, p.57-65

2016

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Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival

Cancer chemotherapy and pharmacology, 2011-11, Vol.68 (5), p.1273-1283

2011

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The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood

The Journal of pharmacology and experimental therapeutics, 2011-08, Vol.338 (2), p.421

2011

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Long Pentraxin 3: Experimental and Clinical Relevance in Cardiovascular Diseases

Mediators of Inflammation, 2013-01, Vol.2013, p.725102-10

2013

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Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo

The Journal of pharmacology and experimental therapeutics, 2008-10, Vol.327 (1), p.10

2008

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Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling

Anticancer research, 2011-11, Vol.31 (11), p.3673-3681

2011

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Cardiovascular Inflammation

Mediators of Inflammation, 2013-01, Vol.2013, p.123513-2

2013

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CYP4F2-Catalyzed Metabolism of Arachidonic Acid Promotes Stromal Cell-Mediated Immunosuppression in Non–Small Cell Lung Cancer

20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis

Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6

Neutrophil-Derived Myeloperoxidase and Hypochlorous Acid Critically Contribute to 20-Hydroxyeicosatetraenoic Acid Increases that Drive Postischemic Angiogenesis

ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma

Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion

CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells

HET0016, a selective inhibitor of 20-HETE synthesis, decreases pro-angiogenic factors and inhibits growth of triple negative breast cancer in mice

20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo

Human cord blood-derived AC133+ progenitor cells preserve endothelial progenitor characteristics after long term in vitro expansion

Eicosanoids: Emerging contributors in stem cell-mediated wound healing

20-HETE in neovascularization

Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer

Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid

Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer

Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation

Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma

Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis

20-HETE contributes to ischemia-induced angiogenesis

Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival

The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood

Long Pentraxin 3: Experimental and Clinical Relevance in Cardiovascular Diseases

Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo

Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling

Cardiovascular Inflammation

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