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Advances in covalent kinase inhibitors

Chemical Society reviews, 2020-05, Vol.49 (9), p.2617-2687

2020

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Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer

Leukemia, 2018-08, Vol.32 (8), p.1713-1726

2018

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A nanostructural view of the cell wall disassembly process during fruit ripening and postharvest storage by atomic force microscopy

Trends in food science & technology, 2019-05, Vol.87, p.47-58

2019

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Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (24), p.9623-9628

2012

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novel mycovirus from Aspergillus fumigatus contains four unique dsRNAs as its genome and is infectious as dsRNA

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (29), p.9100-9105

2015

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Molecular basis for intestinal mucin recognition by galectin‐3 and C‐type lectins

The FASEB journal, 2018-06, Vol.32 (6), p.3301-3320

2018

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Lanthanide-Doped Upconversion Nanoparticles: Exploring A Treasure Trove of NIR-Mediated Emerging Applications

ACS applied materials & interfaces, 2023-01, Vol.15 (2), p.2499-2528

2023

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Direct Targeting Options for STAT3 and STAT5 in Cancer

Cancers, 2019-12, Vol.11 (12), p.1930

2019

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A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes

Biochemical pharmacology, 2010-05, Vol.79 (10), p.1398-1409

2010

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STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Cancer discovery, 2016-04, Vol.6 (4), p.414-429

2016

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Pharmacologic inhibition of STAT5 in acute myeloid leukemia

Leukemia, 2018-05, Vol.32 (5), p.1135-1146

2018

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Structural changes in cell wall pectins during strawberry fruit development

Plant physiology and biochemistry, 2017-09, Vol.118, p.55-63

2017

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Changes in Signal Transducer and Activator of Transcription 3 (STAT3) Dynamics Induced by Complexation with Pharmacological Inhibitors of Src Homology 2 (SH2) Domain Dimerization

The Journal of biological chemistry, 2014-11, Vol.289 (47), p.32538-32547

2014

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Discovery of YSR734: A Covalent HDAC Inhibitor with Cellular Activity in Acute Myeloid Leukemia and Duchenne Muscular Dystrophy

Journal of medicinal chemistry, 2023-12, Vol.66 (24), p.16658-16679

2023

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An Excimer-Based, Turn-On Fluorescent Sensor for the Selective Detection of Diphosphorylated Proteins in Aqueous Solution and Polyacrylamide Gels

Journal of the American Chemical Society, 2014-01, Vol.136 (4), p.1234-1237

2014

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Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein

ChemMedChem, 2008-08, Vol.3 (8), p.1159-1168

2008

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Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity

PloS one, 2016-08, Vol.11 (8), p.e0161202-e0161202

2016

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Structural basis for adaptation of lactobacilli to gastrointestinal mucus

Environmental microbiology, 2014-03, Vol.16 (3), p.888-903

2014

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Inhibiting aberrant Stat3 function with molecular therapeutics: a progress report

Anti-cancer drugs, 2011-02, Vol.22 (2), p.115-127

2011

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Next-Generation Tags for Fluorine Nuclear Magnetic Resonance: Designing Amplification of Chemical Shift Sensitivity

Journal of the American Chemical Society, 2024-02, Vol.146 (5), p.3052-3064

2024

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Recognition of galactan components of pectin by galectin‐3

The FASEB journal, 2009-02, Vol.23 (2), p.415-424

2009

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Histone deacetylase inhibitors as a potential new treatment for psoriatic disease and other inflammatory conditions

Critical reviews in clinical laboratory sciences, 2023-06, Vol.60 (4), p.300-320

2023

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Structural Implications of STAT3 and STAT5 SH2 Domain Mutations

Cancers, 2019-11, Vol.11 (11), p.1757

2019

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Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T‑Cell Prolymphocytic Leukemia

Journal of medicinal chemistry, 2021-06, Vol.64 (12), p.8486-8509

2021

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Characterization of Conformationally Constrained Benzanilide Scaffolds for Potent and Selective HDAC8 Targeting

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.8634-8648

2020

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Advances in covalent kinase inhibitors

Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer

A nanostructural view of the cell wall disassembly process during fruit ripening and postharvest storage by atomic force microscopy

Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

novel mycovirus from Aspergillus fumigatus contains four unique dsRNAs as its genome and is infectious as dsRNA

Molecular basis for intestinal mucin recognition by galectin‐3 and C‐type lectins

Lanthanide-Doped Upconversion Nanoparticles: Exploring A Treasure Trove of NIR-Mediated Emerging Applications

Direct Targeting Options for STAT3 and STAT5 in Cancer

A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes

STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Pharmacologic inhibition of STAT5 in acute myeloid leukemia

Structural changes in cell wall pectins during strawberry fruit development

Changes in Signal Transducer and Activator of Transcription 3 (STAT3) Dynamics Induced by Complexation with Pharmacological Inhibitors of Src Homology 2 (SH2) Domain Dimerization

Discovery of YSR734: A Covalent HDAC Inhibitor with Cellular Activity in Acute Myeloid Leukemia and Duchenne Muscular Dystrophy

An Excimer-Based, Turn-On Fluorescent Sensor for the Selective Detection of Diphosphorylated Proteins in Aqueous Solution and Polyacrylamide Gels

Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein

Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity

Structural basis for adaptation of lactobacilli to gastrointestinal mucus

Inhibiting aberrant Stat3 function with molecular therapeutics: a progress report

Next-Generation Tags for Fluorine Nuclear Magnetic Resonance: Designing Amplification of Chemical Shift Sensitivity

Recognition of galactan components of pectin by galectin‐3

Histone deacetylase inhibitors as a potential new treatment for psoriatic disease and other inflammatory conditions

Structural Implications of STAT3 and STAT5 SH2 Domain Mutations

Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T‑Cell Prolymphocytic Leukemia

Characterization of Conformationally Constrained Benzanilide Scaffolds for Potent and Selective HDAC8 Targeting

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