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Enhancement of arachidonic acid signaling pathway by nicotinic acid receptor HM74A

Biochemical and biophysical research communications, 2006-06, Vol.345 (1), p.29-37

2006

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Next-generation spirobenzazepines : Identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies

Bioorganic & medicinal chemistry letters, 2007-12, Vol.17 (23), p.6623-6628

2007

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Sustained aquaretic effect of the V 2 ‐AVP receptor antagonist, RWJ‐351647, in cirrhotic rats with ascites and water retention

British journal of pharmacology, 2005-11, Vol.146 (5), p.654-661

2005

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Pharmacological characterization of RWJ-676070, a dual vasopressin V1A/V2 receptor antagonist

European journal of pharmacology, 2008-08, Vol.590 (1-3), p.333-342

2008

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2,5-Disubstituted 3,4-dihydro-2H-benzo[b][1,4]thiazepines as potent and selective V2 arginine vasopressin receptor antagonists

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (22), p.4031-4034

2003

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Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes

Bioorganic & medicinal chemistry letters, 2018-03, Vol.28 (5), p.841-846

2018

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The Adipose-Derived Insulin Sensitizer Adiponectin Can Activate Intracellular Signaling Independent of the Well Known AdipoR1 or AdipoR2 Receptors

Diabetes (New York, N.Y.), 2018-07, Vol.67 (Supplement_1)

2018

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Synthesis and SAR of 1,3-disubstituted cyclohexylmethyl urea and amide derivatives as non-peptidic motilin receptor antagonists

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3362-3366

2006

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Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (4), p.753-756

2003

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Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (15), p.3272-3278

2017

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Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates

Bioorganic & medicinal chemistry letters, 2004-06, Vol.14 (11), p.2747-2752

2004

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CHARACTERIZATION OF RWJ‐351647, A NOVEL NONPEPTIDE VASOPRESSIN V 2 RECEPTOR ANTAGONIST

Clinical and experimental pharmacology & physiology, 2006-04, Vol.33 (4), p.320-326

2006

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Erratum to “Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes” Bioorg. Med. Chem. Lett. 28 (2018) [841–846]

Bioorganic & medicinal chemistry letters, 2018-05, Vol.28 (9), p.1676-1678

2018

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Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes

ACS medicinal chemistry letters, 2017-09, Vol.8 (9), p.947-952

2017

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Quantification of G-Protein Coupled Receptor Internalization Using G-Protein Coupled Receptor-Green Fluorescent Protein Conjugates with the ArrayScan™ High-Content Screening System

SLAS discovery, 1999-04, Vol.4 (2), p.75-86

1999

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Bridged bicyclic vasopressin receptor antagonists with V2-Selective or dual V1a/V2 activity

Bioorganic & medicinal chemistry letters, 2002-11, Vol.12 (21), p.3081-3084

2002

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Nonsteroidal Progesterone Receptor Ligands. 2. High-Affinity Ligands with Selectivity for Bone Cell Progesterone Receptors

Journal of medicinal chemistry, 1995-12, Vol.38 (25), p.4880-4884

1995

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New progesterone receptor antagonists: Phosphorus-containing 11β-aryl-substituted steroids

Bioorganic & medicinal chemistry, 2006-10, Vol.14 (19), p.6726-6732

2006

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Human TE671 cells express functional motilin receptors

Biotechnology letters, 2001-12, Vol.23 (24), p.2067-2073

2001

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Synthesis and SAR study of novel pseudo-steroids as potent and selective progesterone receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (14), p.3977-3980

2009

Volltextzugriff (PDF)

Pharmacological characterization of RWJ-676070, a dual vasopressin V 1A/V 2 receptor antagonist

European journal of pharmacology, 2008-08, Vol.590 (1), p.333-342

2008

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The Mating-induced Release of Prolactin: A Unique Neuroendrocine Response

Endocrine reviews, 1983-01, Vol.4 (1), p.44-61

1983

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Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1471-1474

2007

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Novel phosphorus-containing 17β-side chain mifepristone analogues as progesterone receptor antagonists

Steroids, 2006-11, Vol.71 (11), p.949-954

2006

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Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity

Enhancement of arachidonic acid signaling pathway by nicotinic acid receptor HM74A

Next-generation spirobenzazepines : Identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies

Sustained aquaretic effect of the V 2 ‐AVP receptor antagonist, RWJ‐351647, in cirrhotic rats with ascites and water retention

Pharmacological characterization of RWJ-676070, a dual vasopressin V1A/V2 receptor antagonist

2,5-Disubstituted 3,4-dihydro-2H-benzo[b][1,4]thiazepines as potent and selective V2 arginine vasopressin receptor antagonists

Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes

The Adipose-Derived Insulin Sensitizer Adiponectin Can Activate Intracellular Signaling Independent of the Well Known AdipoR1 or AdipoR2 Receptors

Synthesis and SAR of 1,3-disubstituted cyclohexylmethyl urea and amide derivatives as non-peptidic motilin receptor antagonists

Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists

Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists

Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates

CHARACTERIZATION OF RWJ‐351647, A NOVEL NONPEPTIDE VASOPRESSIN V 2 RECEPTOR ANTAGONIST

Erratum to “Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes” Bioorg. Med. Chem. Lett. 28 (2018) [841–846]

Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes

Quantification of G-Protein Coupled Receptor Internalization Using G-Protein Coupled Receptor-Green Fluorescent Protein Conjugates with the ArrayScan™ High-Content Screening System

Bridged bicyclic vasopressin receptor antagonists with V2-Selective or dual V1a/V2 activity

Nonsteroidal Progesterone Receptor Ligands. 2. High-Affinity Ligands with Selectivity for Bone Cell Progesterone Receptors

New progesterone receptor antagonists: Phosphorus-containing 11β-aryl-substituted steroids

Human TE671 cells express functional motilin receptors

Synthesis and SAR study of novel pseudo-steroids as potent and selective progesterone receptor antagonists

Pharmacological characterization of RWJ-676070, a dual vasopressin V 1A/V 2 receptor antagonist

The Mating-induced Release of Prolactin: A Unique Neuroendrocine Response

Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist

Novel phosphorus-containing 17β-side chain mifepristone analogues as progesterone receptor antagonists

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