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Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator

Drug metabolism and disposition, 2005-06, Vol.33 (6), p.866-872

2005

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Increased degradation rate of nitrososureas in media containing carbonate

In vitro cellular & developmental biology. Animal, 2009, Vol.45 (1-2), p.32-34

2009

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Dissolution rate-limited absorption and complete bioavailability of roquinimex in man

Biopharmaceutics & drug disposition, 1999-10, Vol.20 (7), p.347-354

1999

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Phase I Clinical and Pharmacologic Trial of Intravenous Estramustine Phosphate

Journal of clinical oncology, 2002-02, Vol.20 (4), p.1115-1127

Hudes, G.

2002

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Man-made superantigens: Tumor-selective agents for T-cell-based therapy

Advanced drug delivery reviews, 1998-04, Vol.31 (1), p.131-142

1998

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Absorption and disposition including enterohepatic circulation of (14C) roquinimex after oral administration to healthy volunteers

Biopharmaceutics & drug disposition, 2000-03, Vol.21 (2), p.53-67

2000

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Release of 17-beta-oestradiol from a vaginal ring in postmenopausal women: pharmacokinetic evaluation

Gynecologic and obstetric investigation, 1994, Vol.38 (4), p.253-260

1994

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Distribution of estramustine in the BT4C rat glioma model

Cancer chemotherapy and pharmacology, 1998, Vol.41 (4), p.317-325

1998

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The First Clinical Pilot Study of Roquinimex (Linomide®) in Cancer Patients with Special Focus on Immunological Effects

Cancer investigation, 1997, Vol.15 (3), p.204-211

1997

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Determination of the immunomodulator laquinimod in human plasma by liquid chromatography/tandem mass spectrometry; development, validation and application of two methods in clinical pharmacokinetic profiling

Rapid communications in mass spectrometry, 2006-01, Vol.20 (22), p.3313-3318

2006

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Inhibition of Ceruloplasmin by Unsaturated and Aromatic Carboxylic Acids

European journal of biochemistry, 1972-06, Vol.27 (3), p.564-571

1972

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Effect of pH on Electron‐Paramagnetic‐Resonance Spectra of Ceruloplasmin

European journal of biochemistry, 1973-08, Vol.37 (1), p.47-50

1973

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Determination of laquinimod in plasma by coupled-column liquid chromatography with ultraviolet absorbance detection

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003-03, Vol.785 (2), p.311-316

2003

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Inhibition of Ceruloplasmin by Inorganic Anions

European journal of biochemistry, 1972-06, Vol.27 (3), p.572-577

1972

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Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue

Clinical cancer research, 1998-09, Vol.4 (9), p.2079-2084

1998

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Phase I clinical and pharmacologic trial of intravenous estramustine phosphate

Journal of clinical oncology, 2002-02, Vol.20 (4), p.1115-1127

2002

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Possible bone-preserving capacity of high-dose intramuscular depot estrogen as compared to orchidectomy in the treatment of patients with prostatic carcinoma

The Prostate, 1997-05, Vol.31 (3), p.193-197

1997

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pH‐Dependence of the Ceruloplasmin Catalyzed Oxidation of Dimethyl‐p‐phenylenediamine

European journal of biochemistry, 1970-12, Vol.17 (3), p.586-592

1970

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Kinetics of the Interaction between Ceruloplasmin and Reducing Substrates

European journal of biochemistry, 1973-08, Vol.37 (1), p.41-46

1973

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Measurement and characterization of the denitrosation of tauromustine and related nitrosoureas by glutathione transferases in liver cytosol from various species

Carcinogenesis (New York), 1993-06, Vol.14 (6), p.1143-1147

1993

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Pharmacokinetics and testosterone suppression of a single dose of polyestradiol phosphate (Estradurin®) in prostatic cancer patients

The Prostate, 1996-05, Vol.28 (5), p.307-310

1996

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Growth and Cell Survival Following Treatment with Estramustine, Nor-Nitrogen Mustard, Estradiol and Testosterone of a Human Prostatic Cancer Cell Line (DU 145)

The Journal of urology, 1982-04, Vol.127 (4), p.818-822

1982

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Pharmacokinetics of a 16-Hour Transdermal Nicotine Patch

Clinical drug investigation, 1996-10, Vol.12 (4), p.198-206

1996

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Hepatic Intra-Arterial Administration of Doxorubicin and Degradable Starch Microspheres: A pharmacokinetic study in the rat

Acta oncologica, 1994, Vol.33 (1), p.39-42

1994

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Metabolism of a novel nitrosourea, tauromustine, in the rat

Biochemical pharmacology, 1990-05, Vol.39 (9), p.1431-1436

1990

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Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator

Increased degradation rate of nitrososureas in media containing carbonate

Dissolution rate-limited absorption and complete bioavailability of roquinimex in man

Phase I Clinical and Pharmacologic Trial of Intravenous Estramustine Phosphate

Man-made superantigens: Tumor-selective agents for T-cell-based therapy

Absorption and disposition including enterohepatic circulation of (14C) roquinimex after oral administration to healthy volunteers

Release of 17-beta-oestradiol from a vaginal ring in postmenopausal women: pharmacokinetic evaluation

Distribution of estramustine in the BT4C rat glioma model

The First Clinical Pilot Study of Roquinimex (Linomide®) in Cancer Patients with Special Focus on Immunological Effects

Determination of the immunomodulator laquinimod in human plasma by liquid chromatography/tandem mass spectrometry; development, validation and application of two methods in clinical pharmacokinetic profiling

Inhibition of Ceruloplasmin by Unsaturated and Aromatic Carboxylic Acids

Effect of pH on Electron‐Paramagnetic‐Resonance Spectra of Ceruloplasmin

Determination of laquinimod in plasma by coupled-column liquid chromatography with ultraviolet absorbance detection

Inhibition of Ceruloplasmin by Inorganic Anions

Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue

Phase I clinical and pharmacologic trial of intravenous estramustine phosphate

Possible bone-preserving capacity of high-dose intramuscular depot estrogen as compared to orchidectomy in the treatment of patients with prostatic carcinoma

pH‐Dependence of the Ceruloplasmin Catalyzed Oxidation of Dimethyl‐p‐phenylenediamine

Kinetics of the Interaction between Ceruloplasmin and Reducing Substrates

Measurement and characterization of the denitrosation of tauromustine and related nitrosoureas by glutathione transferases in liver cytosol from various species

Pharmacokinetics and testosterone suppression of a single dose of polyestradiol phosphate (Estradurin®) in prostatic cancer patients

Growth and Cell Survival Following Treatment with Estramustine, Nor-Nitrogen Mustard, Estradiol and Testosterone of a Human Prostatic Cancer Cell Line (DU 145)

Pharmacokinetics of a 16-Hour Transdermal Nicotine Patch

Hepatic Intra-Arterial Administration of Doxorubicin and Degradable Starch Microspheres: A pharmacokinetic study in the rat

Metabolism of a novel nitrosourea, tauromustine, in the rat

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