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Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease

American journal of respiratory and critical care medicine, 2015-04, Vol.191 (8), p.902-913

2015

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Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance

Scientific reports, 2018-07, Vol.8 (1), p.10039-17, Article 10039

2018

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Real‐world evidence for preventive effects of statins on cancer incidence: A trans‐Atlantic analysis

Clinical and translational medicine, 2022-02, Vol.12 (2), p.e726-n/a

2022

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Inclusion Complexes of Gold(I)‐Dithiocarbamates with β‐Cyclodextrin: A Journey from Drug Repurposing towards Drug Discovery

Chemistry : a European journal, 2021-08, Vol.27 (47), p.12156-12165

2021

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Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated

Journal of medicinal chemistry, 2019-05, Vol.62 (9), p.4426-4443

2019

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Abstract C043: Targeting TXNRD1 with a competitive inhibitor exposes an Achilles heel of SCLC

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.C043-C043

2019

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Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction

Blood, 2022-03, Vol.139 (9), p.1418-1422

2022

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Parametric modeling and optimal experimental designs for estimating isobolograms for drug interactions in toxicology

Journal of biopharmaceutical statistics, 2018-07, Vol.28 (4), p.763-777

2018

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Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout

Journal of the American Chemical Society, 2022-10, Vol.144 (41), p.18861-18875

2022

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The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines

Archives of toxicology, 2018-08, Vol.92 (8), p.2649-2664

2018

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First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement

Chembiochem : a European journal of chemical biology, 2022-07, Vol.23 (14), p.e202200180-n/a

2022

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Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity

Journal of medicinal chemistry, 2018-10, Vol.61 (19), p.8859-8874

2018

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Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors

ChemMedChem, 2020-07, Vol.15 (13), p.1163-1174

2020

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Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity

ACS chemical biology, 2016-04, Vol.11 (4), p.1001-1011

2016

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Synthesis and Structure‐Activity Relationships of N‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6

ChemMedChem, 2020-01, Vol.15 (1), p.79-95

2020

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Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma

Molecular cancer, 2015-12, Vol.14 (1), p.204-204, Article 204

2015

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The response of Mannheimia haemolytica to iron limitation: Implications for the acquisition of iron in the bovine lung

Veterinary microbiology, 2007-04, Vol.121 (3), p.316-329

2007

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Microarray analysis of Haemophilus parasuis gene expression under in vitro growth conditions mimicking the in vivo environment

Veterinary microbiology, 2005-10, Vol.110 (3), p.255-263

2005

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Identification and characterisation of the dopamine receptor II from the cat flea Ctenocephalides felis (CfDopRII)

Insect biochemistry and molecular biology, 2006-10, Vol.36 (10), p.749-758

2006

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Identification and characterisation of the dopamine receptor II from the cat flea Ctenocephalides felis (CfDopRII)

Insect biochemistry and molecular biology, 2006-10, Vol.36 (10), p.749-758

2006

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Target Identification and Validation in Antiparasitic Drug Discovery

Antiparasitic and Antibacterial Drug Discovery, 2009, p.59-73

2009

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Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease

Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance

Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs

Real‐world evidence for preventive effects of statins on cancer incidence: A trans‐Atlantic analysis

Inclusion Complexes of Gold(I)‐Dithiocarbamates with β‐Cyclodextrin: A Journey from Drug Repurposing towards Drug Discovery

Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated

Abstract C043: Targeting TXNRD1 with a competitive inhibitor exposes an Achilles heel of SCLC

Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction

Parametric modeling and optimal experimental designs for estimating isobolograms for drug interactions in toxicology

Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout

The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines

First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement

Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity

Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors

Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity

Synthesis and Structure‐Activity Relationships of N‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6

Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma

The response of Mannheimia haemolytica to iron limitation: Implications for the acquisition of iron in the bovine lung

Microarray analysis of Haemophilus parasuis gene expression under in vitro growth conditions mimicking the in vivo environment

Identification and characterisation of the dopamine receptor II from the cat flea Ctenocephalides felis (CfDopRII)

Identification and characterisation of the dopamine receptor II from the cat flea Ctenocephalides felis (CfDopRII)

Target Identification and Validation in Antiparasitic Drug Discovery

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