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Pyrrolizidine Esters and Amides as 5-HT4 Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.1125-1139

2006

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NK1.1+ cells mediate the antitumor effects of a dual Toll-like receptor 7/8 agonist in the disseminated B16-F10 melanoma model

Cancer Immunology, Immunotherapy, 2009-04, Vol.58 (4), p.575-587

2009

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SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype

Journal of medicinal chemistry, 1992-04, Vol.35 (8), p.1486-1489

1992

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Effect of 3M-003, an imidazoquinoline, on phagocyte candidacidal activity directly and via induction of peripheral blood mononuclear cell cytokines

FEMS immunology and medical microbiology, 2010-06, Vol.59 (1), p.81-89

2010

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Synthesis and gastrointestinal pharmacology of the 4-fluoro analog of enisoprost

Journal of medicinal chemistry, 1987-11, Vol.30 (11), p.1952-1955

1987

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5-HT4 receptor activation induces relaxation and associated cAMP generation in rat esophagus

European journal of pharmacology, 1992-05, Vol.216 (1), p.47-52

1992

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1,3,4-trisubstituted pyrrolidinones as scaffolds for construction of peptidomimetic cholecystokinin antagonists

Bioorganic & medicinal chemistry letters, 1992-10, Vol.2 (10), p.1251-1256

1992

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Pyrrolizidine Esters and Amides as 5-HT 4 Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.1125-1139

2006

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18-Cycloalkyl analogs of enisoprost

Journal of medicinal chemistry, 1989-05, Vol.32 (5), p.1001-1006

1989

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Synthesis and gastrointestinal pharmacology of a 3E,5Z diene analog of misoprostol

Journal of medicinal chemistry, 1987-01, Vol.30 (1), p.193-197

1987

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Synthesis and gastric antisecretory properties of .alpha.-chain diene derivatives of misoprostol

Journal of medicinal chemistry, 1986-07, Vol.29 (7), p.1195-1201

1986

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Potential antisecretory antidiarrheals. 2. .alpha.2-Adrenergic 2-[(aryloxy)alkyl]imidazolines

Journal of medicinal chemistry, 1990-02, Vol.33 (2), p.614-626

1990

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Potential antisecretory antidiarrheals. 1. .alpha.2-Adrenergic aromatic aminoguanidine hydrazones

Journal of medicinal chemistry, 1988-01, Vol.31 (1), p.138-144

1988

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5-HT4 receptor activation induces relaxation and associated cAMP generation in rat esophagus

European journal of pharmacology, 1992-05, Vol.216 (1), p.47-52

1992

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Effects of several glucocorticosteroids and PDE4 inhibitors on increases in total lung eosinophil peroxidase (EPO) levels following either systemic or intratracheal administration in sephadex- or ovalbumin-induced inflammatory models

Inflammation, 2000-08, Vol.24 (4), p.317-329

2000

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5-HT 4 receptor activation induces relaxation and associated cAMP generation in rat esophagus

European journal of pharmacology, 1992, Vol.216 (1), p.47-52

1992

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Cholecystokinin-mediated ileal electrolyte transport in the guinea pig : characterization of receptor subtype

Gastroenterology (New York, N.Y. 1943), 1991-11, Vol.101 (5), p.1428-1431

1991

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Cholecystokinin-mediated ileal electrolyte transport in the guinea pig

Gastroenterology (New York, N.Y. 1943), 1991-11, Vol.101 (5), p.1428-1431

1991

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New aza(nor)adamantanes are agonists at the newly identified serotonin 5-HT4 receptor and antagonists at the 5-HT3 receptor

Bioorganic & medicinal chemistry letters, 1992-12, Vol.2 (12), p.1613-1618

1992

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Effects of Anionic Surfactants on Hamster Small Intestinal Membrane Structure and Function: Relationship to Surface Activity

Gastroenterology (New York, N.Y. 1943), 1977-09, Vol.73 (3), p.501-511

1977

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Gastrointestinal motility responses to the S and R enantiomers of zacopride, a 5-HT4 agonist and 5-HT3 antagonist

Drug development research, 1992, Vol.26 (4), p.405-417

1992

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Alpha chain unsaturated derivatives of misoprostol

Prostaglandins, 1987, Vol.33, p.17-28

1987

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Inhibition of small intestinal mucosal and smooth muscle cell function by ricinoleic acid and other surfactants

Life sciences (1973), 1975-05, Vol.16 (10), p.1595-1605

1975

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Design and synthesis of agonists and antagonists of the serotonin 5-HT4 receptor subtype

Perspectives in Receptor Research, 1996, Vol.24, p.99-120

1996

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Substituted 2-[(2-benzimidazolylsulfinyl)methyl]anilines as potential inhibitors of H+/K+ ATPase

Journal of medicinal chemistry, 1988-06, Vol.31 (6), p.1215-1220

1988

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Pyrrolizidine Esters and Amides as 5-HT4 Receptor Agonists and Antagonists

NK1.1+ cells mediate the antitumor effects of a dual Toll-like receptor 7/8 agonist in the disseminated B16-F10 melanoma model

SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype

Effect of 3M-003, an imidazoquinoline, on phagocyte candidacidal activity directly and via induction of peripheral blood mononuclear cell cytokines

Synthesis and gastrointestinal pharmacology of the 4-fluoro analog of enisoprost

5-HT4 receptor activation induces relaxation and associated cAMP generation in rat esophagus

1,3,4-trisubstituted pyrrolidinones as scaffolds for construction of peptidomimetic cholecystokinin antagonists

Pyrrolizidine Esters and Amides as 5-HT 4 Receptor Agonists and Antagonists

18-Cycloalkyl analogs of enisoprost

Synthesis and gastrointestinal pharmacology of a 3E,5Z diene analog of misoprostol

Synthesis and gastric antisecretory properties of .alpha.-chain diene derivatives of misoprostol

Potential antisecretory antidiarrheals. 2. .alpha.2-Adrenergic 2-[(aryloxy)alkyl]imidazolines

Potential antisecretory antidiarrheals. 1. .alpha.2-Adrenergic aromatic aminoguanidine hydrazones

5-HT4 receptor activation induces relaxation and associated cAMP generation in rat esophagus

Effects of several glucocorticosteroids and PDE4 inhibitors on increases in total lung eosinophil peroxidase (EPO) levels following either systemic or intratracheal administration in sephadex- or ovalbumin-induced inflammatory models

5-HT 4 receptor activation induces relaxation and associated cAMP generation in rat esophagus

Cholecystokinin-mediated ileal electrolyte transport in the guinea pig : characterization of receptor subtype

Cholecystokinin-mediated ileal electrolyte transport in the guinea pig

New aza(nor)adamantanes are agonists at the newly identified serotonin 5-HT4 receptor and antagonists at the 5-HT3 receptor

Effects of Anionic Surfactants on Hamster Small Intestinal Membrane Structure and Function: Relationship to Surface Activity

Gastrointestinal motility responses to the S and R enantiomers of zacopride, a 5-HT4 agonist and 5-HT3 antagonist

Alpha chain unsaturated derivatives of misoprostol

Inhibition of small intestinal mucosal and smooth muscle cell function by ricinoleic acid and other surfactants

Design and synthesis of agonists and antagonists of the serotonin 5-HT4 receptor subtype

Substituted 2-[(2-benzimidazolylsulfinyl)methyl]anilines as potential inhibitors of H+/K+ ATPase

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