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Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides

Bioorganic chemistry, 2021-10, Vol.115, p.105194-105194, Article 105194

2021

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Synthesis and Cytotoxic Activities of Difluoro-Dimethoxy Chalcones

Anti-cancer agents in medicinal chemistry, 2017-01, Vol.17 (10), p.1426

2017

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Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol

Journal of enzyme inhibition and medicinal chemistry, 2016-11, Vol.31 (6), p.1375-1380

2016

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Cytotoxic effects of Mannich bases via induction of caspase-3 pathway on human oral squamous cell carcinoma

Journal of the Turkish Chemical Society, Section A, Chemistry, 2021, Vol.8 (1), p.187-194

2021

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Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents

Medicinal chemistry research, 2017-09, Vol.26 (9), p.2015-2023

2017

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Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes

Bioorganic chemistry, 2019-05, Vol.86, p.316-321

2019

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Synthesis, molecular modeling, and biological evaluation of 4‐[5‐aryl‐3‐(thiophen‐2‐yl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes

Chemical biology & drug design, 2018-04, Vol.91 (4), p.854-866

2018

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Synthesis and Cytotoxicities of 2-[4-hydroxy-(3,5-bis-aminomethyl)- benzylidene]-indan-1-ones

Letters in drug design & discovery, 2015-12, Vol.12 (10), p.806-812

2015

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Current Pharmaceutical Research on the Significant Pharmacophore Mannich bases in Drug Design

Current topics in medicinal chemistry, 2023-01, Vol.23 (27), p.2590-2608

2023

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Inhibitory effects of novel benzamide derivatives towards acetylcholinesterase enzyme

Journal of the Turkish Chemical Society, Section A, Chemistry, 2021-05, Vol.8 (2), p.429-434

2021

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New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones

Bioorganic chemistry, 2018-12, Vol.81, p.433-439

2018

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Synthesis of benzamide derivatives with thiourea‐substituted benzenesulfonamides as carbonic anhydrase inhibitors

Archiv der Pharmazie (Weinheim), 2021-02, Vol.354 (2), p.e2000230-n/a

2021

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Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines

Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.189-192

2017

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Monoamine Oxidase (MAO) as a Potential Target for Anticancer Drug Design and Development

Molecules (Basel, Switzerland), 2021-10, Vol.26 (19), p.6019

2021

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Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone‐based benzenesulfonamides

Archiv der Pharmazie (Weinheim), 2021-04, Vol.354 (4), p.e2000375-n/a

2021

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Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

Journal of enzyme inhibition and medicinal chemistry, 2016-12, Vol.31 (6), p.1619-1624

2016

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Synthesis and Cytotoxic Activities of a Curcumin Analogue and Its bis- Mannich Derivatives

Letters in drug design & discovery, 2015-01, Vol.12 (8), p.643-649

2015

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Anti-inflammatory Activity of Bis(3-aryl-3-oxo-propyl)methylamine Hydrochloride in Rat

Biological and Pharmaceutical Bulletin, 2007, Vol.30(1), pp.63-67

2007

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Deciphering binding mechanism between bovine serum albumin and new pyrazoline compound K4

Luminescence (Chichester, England), 2020-06, Vol.35 (4), p.534-541

2020

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Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration

Letters in drug design & discovery, 2016-10, Vol.13 (8), p.734-741

2016

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Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides

Journal of enzyme inhibition and medicinal chemistry, 2016-11, Vol.31 (sup2), p.1-5

2016

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New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors

Bioorganic chemistry, 2018-04, Vol.77, p.411-419

2018

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Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors

Letters in drug design & discovery, 2020-01, Vol.17 (10), p.1283-1292

2020

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Synthesis and Cytotoxicity of Novel 3-Aryl-1-(3′-dibenzylaminomethyl-4′-hydroxyphenyl)-propenones and Related Compounds

Chemical and Pharmaceutical Bulletin, 2008/12/01, Vol.56(12), pp.1675-1681

2008

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Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.325-329

2020

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Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides

Synthesis and Cytotoxic Activities of Difluoro-Dimethoxy Chalcones

Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol

Cytotoxic effects of Mannich bases via induction of caspase-3 pathway on human oral squamous cell carcinoma

Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents

Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes

Synthesis, molecular modeling, and biological evaluation of 4‐[5‐aryl‐3‐(thiophen‐2‐yl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes

Synthesis and Cytotoxicities of 2-[4-hydroxy-(3,5-bis-aminomethyl)- benzylidene]-indan-1-ones

Current Pharmaceutical Research on the Significant Pharmacophore Mannich bases in Drug Design

Inhibitory effects of novel benzamide derivatives towards acetylcholinesterase enzyme

New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones

Synthesis of benzamide derivatives with thiourea‐substituted benzenesulfonamides as carbonic anhydrase inhibitors

Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines

Monoamine Oxidase (MAO) as a Potential Target for Anticancer Drug Design and Development

Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone‐based benzenesulfonamides

Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

Synthesis and Cytotoxic Activities of a Curcumin Analogue and Its bis- Mannich Derivatives

Anti-inflammatory Activity of Bis(3-aryl-3-oxo-propyl)methylamine Hydrochloride in Rat

Deciphering binding mechanism between bovine serum albumin and new pyrazoline compound K4

Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration

Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides

New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors

Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors

Synthesis and Cytotoxicity of Novel 3-Aryl-1-(3′-dibenzylaminomethyl-4′-hydroxyphenyl)-propenones and Related Compounds

Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties

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