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Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells

The FEBS journal, 2017-08, Vol.284 (15), p.2324-2344

2017

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In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis

The EMBO journal, 2023-10, Vol.42 (20), p.e110844-e110844

2023

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PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection

Nucleic acids research, 2017-12, Vol.45 (21), p.12325-12339

2017

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Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks

EMBO reports, 2009-08, Vol.10 (8), p.887-893

2009

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53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks

PLoS genetics, 2016-10, Vol.12 (10), p.e1006230-e1006230

2016

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Defects in XRCC4 and KU80 Differentially Affect the Joining of Distal Nonhomologous Ends

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (52), p.20902-20907

2007

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Noncanonical Roles of RAD51

Cells (Basel, Switzerland), 2023-04, Vol.12 (8), p.1169

2023

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Impact of the KU80 Pathway on NHEJ-Induced Genome Rearrangements in Mammalian Cells

Molecular cell, 2004-06, Vol.14 (5), p.611-623

2004

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A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining

Cell reports (Cambridge), 2013-10, Vol.5 (1), p.21-28

2013

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Bcl-2 Inhibits Nuclear Homologous Recombination by Localizing BRCA1 to the Endomembranes

Cancer research (Chicago, Ill.), 2011-05, Vol.71 (10), p.3590-3602

2011

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Von Hippel-Lindau–Coupled and Transcription-Coupled Nucleotide Excision Repair–Dependent Degradation of RNA Polymerase II in Response to Trabectedin

Clinical cancer research, 2008-10, Vol.14 (20), p.6449-6455

2008

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Is homologous recombination really an error-free process?

Frontiers in genetics, 2014-06, Vol.5, p.175

2014

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RAD51 protects against nonconservative DNA double-strand break repair through a nonenzymatic function

Nucleic acids research, 2022-03, Vol.50 (5), p.2651-2666

2022

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PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways

Nucleic acids research, 2014-05, Vol.42 (9), p.5616-5632

2014

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A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner

Cell death and differentiation, 2023-05, Vol.30 (5), p.1349-1365

2023

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Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ

Nucleic acids research, 2021-11, Vol.49 (20), p.11728-11745

2021

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WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer

Cancer gene therapy, 2023-08, Vol.30 (8), p.1144-1155

2023

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Reconstitution of the Yeast RNA Polymerase III Transcription System with All Recombinant Factors

The Journal of biological chemistry, 2006-04, Vol.281 (17), p.11685-11692

2006

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Control of alternative end joining by the chromatin remodeler p400 ATPase

Nucleic acids research, 2016-02, Vol.44 (4), p.1657-1668

2016

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RhoB Promotes γH2AX Dephosphorylation and DNA Double-Strand Break Repair

Molecular and cellular biology, 2014-08, Vol.34 (16), p.3144-3155

2014

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Homologous recombination, cancer and the ‘RAD51 paradox’

NAR cancer, 2021-06, Vol.3 (2)

2021

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Combined therapy of colon carcinomas with an oncolytic adenovirus and valproic acid

Oncotarget, 2017-11, Vol.8 (57), p.97344-97360

2017

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Zalypsis (PM00104) is a potent inducer of γ-H2AX foci and reveals the importance of the C ring of trabectedin for transcription-coupled repair inhibition

Molecular cancer therapeutics, 2009-07, Vol.8 (7), p.2007-2014

2009

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AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers

Oncotarget, 2010-12, Vol.1 (8), p.691-699

2010

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Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells

In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection

Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks

53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks

Defects in XRCC4 and KU80 Differentially Affect the Joining of Distal Nonhomologous Ends

Noncanonical Roles of RAD51

Impact of the KU80 Pathway on NHEJ-Induced Genome Rearrangements in Mammalian Cells

A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining

Bcl-2 Inhibits Nuclear Homologous Recombination by Localizing BRCA1 to the Endomembranes

Von Hippel-Lindau–Coupled and Transcription-Coupled Nucleotide Excision Repair–Dependent Degradation of RNA Polymerase II in Response to Trabectedin

Is homologous recombination really an error-free process?

RAD51 protects against nonconservative DNA double-strand break repair through a nonenzymatic function

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways

A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner

Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor

Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ

WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer

Reconstitution of the Yeast RNA Polymerase III Transcription System with All Recombinant Factors

Control of alternative end joining by the chromatin remodeler p400 ATPase

RhoB Promotes γH2AX Dephosphorylation and DNA Double-Strand Break Repair

Homologous recombination, cancer and the ‘RAD51 paradox’

Combined therapy of colon carcinomas with an oncolytic adenovirus and valproic acid

Zalypsis (PM00104) is a potent inducer of γ-H2AX foci and reveals the importance of the C ring of trabectedin for transcription-coupled repair inhibition

AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers

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