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Active Glycogen Synthase in the Liver Prevents High-Fat Diet-Induced Glucose Intolerance, Decreases Food Intake, and Lowers Body Weight

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2574

2023

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Suppression of glycogen synthesis as a treatment for Lafora disease: Establishing the window of opportunity

Neurobiology of disease, 2021-01, Vol.147, p.105173-105173, Article 105173

2021

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Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment

Cell metabolism, 2017-07, Vol.26 (1), p.256-266.e4

2017

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Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora disease

Glia, 2018-10, Vol.66 (10), p.2094-2107

2018

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Effects of hepatic glycogen on food intake and glucose homeostasis are mediated by the vagus nerve in mice

Diabetologia, 2017-06, Vol.60 (6), p.1076-1083

2017

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Exploring the elusive composition of corpora amylacea of human brain

Scientific reports, 2018-09, Vol.8 (1), p.13525-13, Article 13525

2018

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Impairment in Long-Term Memory Formation and Learning-Dependent Synaptic Plasticity in Mice Lacking Glycogen Synthase in the Brain

Journal of cerebral blood flow and metabolism, 2013-04, Vol.33 (4), p.550-556

2013

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AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Biochemical journal, 2012-04, Vol.443 (1), p.193-203

2012

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FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

Nature communications, 2016-04, Vol.7 (1), p.11199-11199, Article 11199

2016

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Liver glycogen reduces food intake and attenuates obesity in a high-fat diet-fed mouse model

Diabetes (New York, N.Y.), 2015-03, Vol.64 (3), p.796-807

2015

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Lack of Neuronal Glycogen Impairs Memory Formation and Learning-Dependent Synaptic Plasticity in Mice

Frontiers in cellular neuroscience, 2019-08, Vol.13, p.374-374

2019

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Hepatic overexpression of protein targeting to glycogen attenuates obesity and improves hyperglycemia in db/db mice

Frontiers in endocrinology (Lausanne), 2022-09, Vol.13, p.969924-969924

2022

Volltextzugriff (PDF)

A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data

Metabolites, 2012-10, Vol.2 (4), p.775-795

2012

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Structural basis for the recruitment of glycogen synthase by glycogenin

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.E2831-E2840

2014

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Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation

Cell reports (Cambridge), 2023-06, Vol.42 (6), p.112578-112578, Article 112578

2023

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Glucose-6-Phosphate―Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis

Diabetes (New York, N.Y.), 2013-12, Vol.62 (12), p.4070-4082

2013

Volltextzugriff (PDF)

Genetic models rule out a major role of beta cell glycogen in the control of glucose homeostasis

Diabetologia, 2016-05, Vol.59 (5), p.1012-1020

2016

Volltextzugriff (PDF)

HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data

PLoS computational biology, 2016-04, Vol.12 (4), p.e1004899-e1004899

2016

Volltextzugriff (PDF)

Brain glycogen in health and disease

Molecular aspects of medicine, 2015-12, Vol.46, p.70-77

2015

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Deleterious effects of neuronal accumulation of glycogen in flies and mice

EMBO molecular medicine, 2012-08, Vol.4 (8), p.719-729

2012

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Glucose and fructose have sugar-specific effects in both liver and skeletal muscle in vivo: a role for liver fructokinase

PloS one, 2014-10, Vol.9 (10), p.e109726-e109726

2014

Volltextzugriff (PDF)

Increased liver glycogen levels enhance exercise capacity in mice

The Journal of biological chemistry, 2021-08, Vol.297 (2), p.100976-100976, Article 100976

2021

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A new level of regulation in gluconeogenesis: metabolic state modulates the intracellular localization of aldolase B and its interaction with liver fructose-1,6-bisphosphatase

Biochemical journal, 2015-12, Vol.472 (2), p.225-237

2015

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Tungstate reduces the expression of gluconeogenic enzymes in STZ rats

PloS one, 2012-08, Vol.7 (8), p.e42305-e42305

2012

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Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice

The Journal of biological chemistry, 2021-01, Vol.296, p.100498-100498, Article 100498

2021

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Active Glycogen Synthase in the Liver Prevents High-Fat Diet-Induced Glucose Intolerance, Decreases Food Intake, and Lowers Body Weight

Suppression of glycogen synthesis as a treatment for Lafora disease: Establishing the window of opportunity

Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment

Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora disease

Effects of hepatic glycogen on food intake and glucose homeostasis are mediated by the vagus nerve in mice

Exploring the elusive composition of corpora amylacea of human brain

Impairment in Long-Term Memory Formation and Learning-Dependent Synaptic Plasticity in Mice Lacking Glycogen Synthase in the Brain

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

Liver glycogen reduces food intake and attenuates obesity in a high-fat diet-fed mouse model

Lack of Neuronal Glycogen Impairs Memory Formation and Learning-Dependent Synaptic Plasticity in Mice

Hepatic overexpression of protein targeting to glycogen attenuates obesity and improves hyperglycemia in db/db mice

A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data

Structural basis for the recruitment of glycogen synthase by glycogenin

Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation

Glucose-6-Phosphate―Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis

Genetic models rule out a major role of beta cell glycogen in the control of glucose homeostasis

HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data

Brain glycogen in health and disease

Deleterious effects of neuronal accumulation of glycogen in flies and mice

Glucose and fructose have sugar-specific effects in both liver and skeletal muscle in vivo: a role for liver fructokinase

Increased liver glycogen levels enhance exercise capacity in mice

A new level of regulation in gluconeogenesis: metabolic state modulates the intracellular localization of aldolase B and its interaction with liver fructose-1,6-bisphosphatase

Tungstate reduces the expression of gluconeogenic enzymes in STZ rats

Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice

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