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Quinolinic acid, the inescapable neurotoxin

The FEBS journal, 2012-04, Vol.279 (8), p.1356-1365

Guillemin, Gilles J.

2012

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Age-associated changes in oxidative stress and NAD+ metabolism in human tissue

PloS one, 2012-07, Vol.7 (7), p.e42357-e42357

2012

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The non-protein amino acid BMAA is misincorporated into human proteins in place of L-serine causing protein misfolding and aggregation

PloS one, 2013-09, Vol.8 (9), p.e75376

2013

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Neuroinflammation and neuronal loss precede Aβ plaque deposition in the hAPP-J20 mouse model of Alzheimer's disease

PloS one, 2013-04, Vol.8 (4), p.e59586-e59586

2013

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Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats

PloS one, 2011-04, Vol.6 (4), p.e19194-e19194

2011

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Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

PloS one, 2015-06, Vol.10 (6), p.e0131389-e0131389

2015

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Molecular imaging of microglial activation in amyotrophic lateral sclerosis

PloS one, 2012-12, Vol.7 (12), p.e52941-e52941

2012

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A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression

PloS one, 2018-06, Vol.13 (6), p.e0198116-e0198116

2018

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Tryptophan Predicts the Risk for Future Type 2 Diabetes

PloS one, 2016-09, Vol.11 (9), p.e0162192-e0162192

2016

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Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain

PloS one, 2013-04, Vol.8 (4), p.e59749-e59749

2013

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Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases

Neuropharmacology, 2017-01, Vol.112 (Pt B), p.373-388

2017

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Effects of Exhaustive Aerobic Exercise on Tryptophan-Kynurenine Metabolism in Trained Athletes

PloS one, 2016-04, Vol.11 (4), p.e0153617-e0153617

2016

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Plasma kynurenines and prognosis in patients with heart failure

PloS one, 2020-01, Vol.15 (1), p.e0227365-e0227365

2020

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Dietary BMAA exposure in an amyotrophic lateral sclerosis cluster from southern France

PloS one, 2013-12, Vol.8 (12), p.e83406

2013

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Long-term dietary supplementation of pomegranates, figs and dates alleviate neuroinflammation in a transgenic mouse model of Alzheimer's disease

PloS one, 2015-03, Vol.10 (3), p.e0120964

2015

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The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

PloS one, 2009-07, Vol.4 (7), p.e6344

2009

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Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification

Journal of leukocyte biology, 2004-03, Vol.75 (3), p.388-397

2004

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The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

Oxidative medicine and cellular longevity, 2016-01, Vol.2016 (2016), p.1-15

2016

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The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?

Trends in molecular medicine, 2021-10, Vol.27 (10), p.946-954

2021

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Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia

Molecular psychiatry, 2020-11, Vol.25 (11), p.2860-2872

2020

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Importance of the dysregulation of the kynurenine pathway on cognition in schizophrenia: a systematic review of clinical studies

European archives of psychiatry and clinical neuroscience, 2023-09, Vol.273 (6), p.1317-1328

2023

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Involvement of the kynurenine pathway in human glioma pathophysiology

PloS one, 2014-11, Vol.9 (11), p.e112945

2014

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Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreased body weight without negative influence on densitometry and mandibular bone biomechanical endurance in young rats

PloS one, 2019-12, Vol.14 (12), p.e0226205-e0226205

2019

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The Other Side of the Coin: What Beneficial Microbes Can Teach Us about Pathogenic Potential

Journal of molecular biology, 2019-07, Vol.431 (16), p.2946-2956

2019

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Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease

Journal of neuroinflammation, 2009-12, Vol.6 (1), p.36-36, Article 36

2009

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Quinolinic acid, the inescapable neurotoxin

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue

The non-protein amino acid BMAA is misincorporated into human proteins in place of L-serine causing protein misfolding and aggregation

Neuroinflammation and neuronal loss precede Aβ plaque deposition in the hAPP-J20 mouse model of Alzheimer's disease

Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

Molecular imaging of microglial activation in amyotrophic lateral sclerosis

A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression

Tryptophan Predicts the Risk for Future Type 2 Diabetes

Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain

Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases

Effects of Exhaustive Aerobic Exercise on Tryptophan-Kynurenine Metabolism in Trained Athletes

Plasma kynurenines and prognosis in patients with heart failure

Dietary BMAA exposure in an amyotrophic lateral sclerosis cluster from southern France

Long-term dietary supplementation of pomegranates, figs and dates alleviate neuroinflammation in a transgenic mouse model of Alzheimer's disease

The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?

Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia

Importance of the dysregulation of the kynurenine pathway on cognition in schizophrenia: a systematic review of clinical studies

Involvement of the kynurenine pathway in human glioma pathophysiology

Chronic dietary supplementation with kynurenic acid, a neuroactive metabolite of tryptophan, decreased body weight without negative influence on densitometry and mandibular bone biomechanical endurance in young rats

The Other Side of the Coin: What Beneficial Microbes Can Teach Us about Pathogenic Potential

Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease

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