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Chromatographic, Electrophoretic, and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals

Analytical chemistry (Washington), 2016-01, Vol.88 (1), p.480-507

2016

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Supercritical fluid chromatography – Mass spectrometry in metabolomics: Past, present, and future perspectives

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-12, Vol.1161, p.122444-122444, Article 122444

2020

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Multi‐dimensional technology – Recent advances and applications for biotherapeutic characterization

Journal of separation science, 2024-03, Vol.47 (5), p.e2300928-n/a

2024

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Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches

Analyst (London), 2021-02, Vol.146 (3), p.747-769

2021

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Recent Advances in Chromatography for Pharmaceutical Analysis

Analytical chemistry (Washington), 2019-01, Vol.91 (1), p.210-239

2019

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Metamorphosis of supercritical fluid chromatography: A viable tool for the analysis of polar compounds?

TrAC, Trends in analytical chemistry (Regular ed.), 2021-08, Vol.141, p.116304, Article 116304

2021

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Supercritical fluid chromatography – Mass spectrometry: Recent evolution and current trends

TrAC, Trends in analytical chemistry (Regular ed.), 2019-09, Vol.118, p.731-738

2019

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Analytical strategies for the determination of amino acids: Past, present and future trends

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019-11, Vol.1132, p.121819-121819, Article 121819

2019

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Ion-exchange chromatography for the characterization of biopharmaceuticals

Journal of pharmaceutical and biomedical analysis, 2015-09, Vol.113, p.43-55

2015

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Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis

Journal of pharmaceutical and biomedical analysis, 2014-01, Vol.87, p.105-119

2014

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Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017-10, Vol.1065-1066, p.119-128

2017

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Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part I: Salt gradient approach

Journal of pharmaceutical and biomedical analysis, 2015-01, Vol.102, p.33-44

2015

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Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017-10, Vol.1065-1066, p.35-43

2017

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Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products

Journal of pharmaceutical and biomedical analysis, 2016-10, Vol.130, p.3-18

2016

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Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part II: pH gradient approach

Journal of pharmaceutical and biomedical analysis, 2015-01, Vol.102, p.282-289

2015

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Therapeutic Fc‐fusion proteins: Current analytical strategies

Journal of separation science, 2021-01, Vol.44 (1), p.35-62

2021

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What are the current solutions for interfacing supercritical fluid chromatography and mass spectrometry?

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018-04, Vol.1083, p.160-170

2018

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Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody products

Journal of separation science, 2022-06, Vol.45 (12), p.1997-2007

2022

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Streamlined Characterization of an Antibody–Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry

Analytical chemistry (Washington), 2019-12, Vol.91 (23), p.14896-14903

2019

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Unraveling the mysteries of modern size exclusion chromatography - the way to achieve confident characterization of therapeutic proteins

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018-08, Vol.1092, p.368-378

2018

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Comparison of the most recent chromatographic approaches applied for fast and high resolution separations: Theory and practice

Journal of Chromatography A, 2015-08, Vol.1408, p.1-14

2015

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A simple mathematical treatment for predicting linear solvent strength behavior in gradient elution: Application to biomolecules

Journal of separation science, 2022-09, Vol.45 (17), p.3276-3285

2022

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Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography

Journal of pharmaceutical and biomedical analysis, 2013-10, Vol.84, p.215-223

2013

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A generic workflow for the characterization of therapeutic monoclonal antibodies—application to daratumumab

Analytical and bioanalytical chemistry, 2019-07, Vol.411 (19), p.4615-4627

2019

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Expanding the range of sub/supercritical fluid chromatography: Advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis

Journal of Chromatography A, 2021-04, Vol.1642, p.462048, Article 462048

2021

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Chromatographic, Electrophoretic, and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals

Supercritical fluid chromatography – Mass spectrometry in metabolomics: Past, present, and future perspectives

Multi‐dimensional technology – Recent advances and applications for biotherapeutic characterization

Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches

Recent Advances in Chromatography for Pharmaceutical Analysis

Metamorphosis of supercritical fluid chromatography: A viable tool for the analysis of polar compounds?

Supercritical fluid chromatography – Mass spectrometry: Recent evolution and current trends

Analytical strategies for the determination of amino acids: Past, present and future trends

Ion-exchange chromatography for the characterization of biopharmaceuticals

Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis

Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies

Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part I: Salt gradient approach

Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation

Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products

Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part II: pH gradient approach

Therapeutic Fc‐fusion proteins: Current analytical strategies

What are the current solutions for interfacing supercritical fluid chromatography and mass spectrometry?

Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody products

Streamlined Characterization of an Antibody–Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry

Unraveling the mysteries of modern size exclusion chromatography - the way to achieve confident characterization of therapeutic proteins

Comparison of the most recent chromatographic approaches applied for fast and high resolution separations: Theory and practice

A simple mathematical treatment for predicting linear solvent strength behavior in gradient elution: Application to biomolecules

Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography

A generic workflow for the characterization of therapeutic monoclonal antibodies—application to daratumumab

Expanding the range of sub/supercritical fluid chromatography: Advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis

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