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Notch signaling in development and disease

Clinical genetics, 2003-12, Vol.64 (6), p.461-472

2003

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V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors

Genes & development, 1996-08, Vol.10 (16), p.2038-2054

1996

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Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts

Leukemia, 2015-01, Vol.29 (1), p.177-187

2015

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Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

Molecular and Cellular Biology, 1996-10, Vol.16 (10), p.5507-5517

1996

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Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

Nature genetics, 1996-04, Vol.12 (4), p.448-451

1996

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Rescue of T Cell-Specific V(D)J Recombination in SCID Mice by DNA-Damaging Agents

Science (American Association for the Advancement of Science), 1994-10, Vol.266 (5184), p.450-455

1994

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Intrathymic Maturation of Murine T Lymphocytes from CD8+ Precursors

Proceedings of the National Academy of Sciences - PNAS, 1989-10, Vol.86 (19), p.7542-7546

1989

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Subversion of the T/B Lineage Decision in the Thymus by Lunatic Fringe-Mediated Inhibition of Notch-1

Immunity (Cambridge, Mass.), 2001-08, Vol.15 (2), p.225-236

2001

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Irradiation Promotes V(D)J Joining and RAG-Dependent Neoplastic Transformation in SCID T-Cell Precursors

Molecular and Cellular Biology, 2001-01, Vol.21 (2), p.400-413

2001

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Functions of notch signaling in the immune system: consensus and controversies

Annual review of immunology, 2010-01, Vol.28 (1), p.343-365

2010

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The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk : A severe combined immune deficiency (SCID) murine model

Cancer research (Chicago, Ill.), 1997-10, Vol.57 (19), p.4408-4413

1997

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The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice

Cancer cell, 2003, Vol.3 (1), p.37-50

2003

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Fyn Can Partially Substitute for Lck in T Lymphocyte Development

Immunity (Cambridge, Mass.), 1996-11, Vol.5 (5), p.417-428

1996

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Transgenic Expression of Numb Inhibits Notch Signaling in Immature Thymocytes But Does Not Alter T Cell Fate Specification

The Journal of immunology (1950), 2002-04, Vol.168 (7), p.3173-3180

2002

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Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

Nature communications, 2021-02, Vol.12 (1), p.1054-13, Article 1054

2021

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T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages

The Journal of experimental medicine, 1990-09, Vol.172 (3), p.835-845

1990

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Positive selection of CD4 + and CD8 + T cells

Current opinion in immunology, 1996-04, Vol.8 (2), p.225-232

Guidos, Cynthia J

1996

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Fine-tuning Notch1 activation by endocytosis and glycosylation

Seminars in immunology, 2003-04, Vol.15 (2), p.99-106

2003

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TCR engagement of CD4+CD8+ thymocytes in vitro induces early aspects of positive selection, but not apoptosis

The Journal of immunology (1950), 1997-01, Vol.158 (1), p.65-75

1997

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Requirement for Notch1 signals at sequential early stages of intrathymic T cell development

Nature Immunology, 2005-07, Vol.6 (7), p.671-679

2005

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Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway

The Journal of experimental medicine, 1995-03, Vol.181 (3), p.1187-1195

1995

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In vitro maturation of clonal CD4+CD8+ cell lines in response to TCR engagement

The Journal of immunology (1950), 1995-05, Vol.154 (10), p.5011-5022

1995

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Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor

The Journal of immunology (1950), 1989-06, Vol.142 (11), p.3773-3780

1989

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ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection

Immunological reviews, 2006-02, Vol.209 (1), p.142-158

2006

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Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions

Immunological reviews, 2006-02, Vol.209 (1), p.76-94

2006

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Notch signaling in development and disease

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors

Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

Rescue of T Cell-Specific V(D)J Recombination in SCID Mice by DNA-Damaging Agents

Intrathymic Maturation of Murine T Lymphocytes from CD8+ Precursors

Subversion of the T/B Lineage Decision in the Thymus by Lunatic Fringe-Mediated Inhibition of Notch-1

Irradiation Promotes V(D)J Joining and RAG-Dependent Neoplastic Transformation in SCID T-Cell Precursors

Functions of notch signaling in the immune system: consensus and controversies

The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk : A severe combined immune deficiency (SCID) murine model

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice

Fyn Can Partially Substitute for Lck in T Lymphocyte Development

Transgenic Expression of Numb Inhibits Notch Signaling in Immature Thymocytes But Does Not Alter T Cell Fate Specification

Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages

Positive selection of CD4 + and CD8 + T cells

Fine-tuning Notch1 activation by endocytosis and glycosylation

TCR engagement of CD4+CD8+ thymocytes in vitro induces early aspects of positive selection, but not apoptosis

Requirement for Notch1 signals at sequential early stages of intrathymic T cell development

Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway

In vitro maturation of clonal CD4+CD8+ cell lines in response to TCR engagement

Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor

ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection

Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions

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