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From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

Molecular biology of the cell, 2016-02, Vol.27 (3), p.424-433

2016

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Identification of a Urate Transporter, ABCG2, with a Common Functional Polymorphism Causing Gout

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (25), p.10338-10342

2009

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Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease

Kidney international, 2016-07, Vol.90 (1), p.90-99

2016

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Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (18), p.8440-8445

2010

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Drosophila TRPA1 Channel Is Required to Avoid the Naturally Occurring Insect Repellent Citronellal

Current biology, 2010-09, Vol.20 (18), p.1672-1678

2010

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Rescue of NBD2 mutants N1303K and S1235R of CFTR by small-molecule correctors and transcomplementation

PloS one, 2015-03, Vol.10 (3), p.e0119796-e0119796

2015

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Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR

Cellular physiology and biochemistry, 2018-01, Vol.51 (3), p.1489-1499

2018

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Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (13), p.5223-5228

2013

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Correcting the cystic fibrosis disease mutant, A455E CFTR

PloS one, 2014-01, Vol.9 (1), p.e85183-e85183

2014

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WNK4 Enhances the Degradation of NCC through a Sortilin-Mediated Lysosomal Pathway

Journal of the American Society of Nephrology, 2010, Vol.21 (1), p.82-92

2010

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Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator

Molecular biology of the cell, 2010-04, Vol.21 (7), p.1178-1187

2010

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Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway

Nature immunology, 2004-04, Vol.5 (4), p.388-392

2004

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Dexamethasone regulates CFTR expression in Calu-3 cells with the involvement of chaperones HSP70 and HSP90

PloS one, 2012-12, Vol.7 (12), p.e47405

2012

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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

Nature (London), 2000-12, Vol.408 (6815), p.990-994

2000

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High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease

Kidney international, 2005-08, Vol.68 (2), p.642-652

2005

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Impaired acidification in early endosomes of ClC-5 deficient proximal tubule

Biochemical and biophysical research communications, 2005-04, Vol.329 (3), p.941-946

2005

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CFTR Controls the Activity of NF-κB by Enhancing the Degradation of TRADD

Cellular physiology and biochemistry, 2016-12, Vol.40 (5), p.1063-1078

2016

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Loss of Chloride Channel ClC-5 Impairs Endocytosis by Defective Trafficking of Megalin and Cubilin in Kidney Proximal Tubules

Proceedings of the National Academy of Sciences - PNAS, 2003-07, Vol.100 (14), p.8472-8477

2003

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Gene Therapy for Cystic Fibrosis Paved the Way for the Use of Adeno-Associated Virus in Gene Therapy

Human gene therapy, 2020-05, Vol.31 (9-10), p.538-541

2020

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Polycystin 2 Interacts with Type I Inositol 1,4,5-Trisphosphate Receptor to Modulate Intracellular Ca2+ Signaling

The Journal of biological chemistry, 2005-12, Vol.280 (50), p.41298-41306

2005

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cAMP regulates cell proliferation and cyst formation in autosomal polycystic kidney disease cells

Journal of the American Society of Nephrology, 2000-07, Vol.11 (7), p.1179-1187

2000

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Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion

The Journal of general physiology, 2010-01, Vol.135 (1), p.43-58

2010

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Restoration of F508-del Function by Transcomplementation: The Partners Meet in the Endoplasmic Reticulum

Cellular physiology and biochemistry, 2019, Vol.52 (6), p.1267-1279

2019

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Amelioration of airway and GI disease in G551D-CF ferrets by AAV1 and AAV6

Gene therapy, 2024-09, Vol.31 (9-10), p.499-510

2024

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Adeno-Associated Virus (AAV) gene therapy for cystic fibrosis: current barriers and recent developments

Expert opinion on biological therapy, 2017-10, Vol.17 (10), p.1265-1273

2017

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From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

Identification of a Urate Transporter, ABCG2, with a Common Functional Polymorphism Causing Gout

Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease

Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons

Drosophila TRPA1 Channel Is Required to Avoid the Naturally Occurring Insect Repellent Citronellal

Rescue of NBD2 mutants N1303K and S1235R of CFTR by small-molecule correctors and transcomplementation

Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR

Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules

Correcting the cystic fibrosis disease mutant, A455E CFTR

WNK4 Enhances the Degradation of NCC through a Sortilin-Mediated Lysosomal Pathway

Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator

Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway

Dexamethasone regulates CFTR expression in Calu-3 cells with the involvement of chaperones HSP70 and HSP90

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease

Impaired acidification in early endosomes of ClC-5 deficient proximal tubule

CFTR Controls the Activity of NF-κB by Enhancing the Degradation of TRADD

Loss of Chloride Channel ClC-5 Impairs Endocytosis by Defective Trafficking of Megalin and Cubilin in Kidney Proximal Tubules

Gene Therapy for Cystic Fibrosis Paved the Way for the Use of Adeno-Associated Virus in Gene Therapy

Polycystin 2 Interacts with Type I Inositol 1,4,5-Trisphosphate Receptor to Modulate Intracellular Ca2+ Signaling

cAMP regulates cell proliferation and cyst formation in autosomal polycystic kidney disease cells

Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion

Restoration of F508-del Function by Transcomplementation: The Partners Meet in the Endoplasmic Reticulum

Amelioration of airway and GI disease in G551D-CF ferrets by AAV1 and AAV6

Adeno-Associated Virus (AAV) gene therapy for cystic fibrosis: current barriers and recent developments

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