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High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease

Kidney international, 2005-08, Vol.68 (2), p.642-652

2005

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Impaired acidification in early endosomes of ClC-5 deficient proximal tubule

Biochemical and biophysical research communications, 2005-04, Vol.329 (3), p.941-946

2005

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Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion

The Journal of general physiology, 2010-01, Vol.135 (1), p.43-58

2010

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Extracellular Acidification Alters Lysosomal Trafficking in Human Breast Cancer Cells

Neoplasia (New York, N.Y.), 2003-11, Vol.5 (6), p.533-545

2003

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The Loss of the Chloride Channel, ClC-5, Delays Apical Iodide Efflux and Induces a Euthyroid Goiter in the Mouse Thyroid Gland

Endocrinology (Philadelphia), 2006-03, Vol.147 (3), p.1287-1296

2006

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ClC-5: role in endocytosis in the proximal tubule

American journal of physiology. Renal physiology, 2005-10, Vol.289 (4), p.F850-F862

2005

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A New Insight into Pathophysiological Mechanisms of Zinc in Diarrhea

Annals of the New York Academy of Sciences, 2009-05, Vol.1165 (1), p.279-284

2009

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Mechanisms of Disease: what can mouse models tell us about the molecular processes underlying Dent disease?

Nature clinical practice. Nephrology, 2007-08, Vol.3 (8), p.449-455

Guggino, Sandra E

2007

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NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity

American Journal of Physiology: Cell Physiology, 2011-04, Vol.300 (4), p.C771-C782

2011

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The ClC‐5 Knockout Mouse Model of Dent's Disease Has Renal Hypercalciuria and Increased Bone Turnover

Journal of bone and mineral research, 2003-04, Vol.18 (4), p.615-623

2003

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Chloride Channel (Clc)-5 Is Necessary for Exocytic Trafficking of Na+/H+ Exchanger 3 (NHE3)

The Journal of biological chemistry, 2011-07, Vol.286 (26), p.22833-22845

2011

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Can we generate new hypotheses about Dent's disease from gene analysis of a mouse model?

Experimental physiology, 2009-02, Vol.94 (2), p.191-196

Guggino, Sandra E.

2009

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Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins

Physiological genomics, 2004-01, Vol.16 (2), p.204-211

2004

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Expression of a Truncated Cystic Fibrosis Transmembrane Conductance Regulator with an AAV5-pseudotyped Vector in Primates

Molecular therapy, 2007-04, Vol.15 (4), p.756-763

2007

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L-type calcium channel activity in osteoblast cells is regulated by the actin cytoskeleton independent of protein trafficking

Journal of bone and mineral metabolism, 2011-09, Vol.29 (5), p.515-525

2011

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Clcn5 Knockout Mice Exhibit Novel Immunomodulatory Effects and Are More Susceptible to Dextran Sulfate Sodium-Induced Colitis

The Journal of immunology (1950), 2010-04, Vol.184 (7), p.3988-3996

2010

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Transcriptional adaptation to Clcn5 knockout in proximal tubules of mouse kidney

Physiological genomics, 2008-05, Vol.33 (3), p.341-354

2008

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Organic Solutes Rescue the Functional Defect in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator

The Journal of biological chemistry, 2003-12, Vol.278 (51), p.51232-51242

2003

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Absence of ClC5 in Knockout Mice Leads to Glycosuria, Impaired Renal Glucose Handling and Low Proximal Tubule GLUT2 Protein Expression

Cellular physiology and biochemistry, 2007-01, Vol.20 (5), p.455-464

2007

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The mRNA of L-Type Calcium Channel Elevated in Colon Cancer : Protein Distribution in Normal and Cancerous Colon

The American journal of pathology, 2000-11, Vol.157 (5), p.1549-1562

2000

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Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats

Journal of applied physiology (1985), 2001-04, Vol.90 (4), p.1489-1496

2001

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Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques

Molecular therapy, 2003-12, Vol.8 (6), p.918-926

2003

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983 Clc-5 Knockout Mice Are More Susceptible to Dextran Sulphate Sodium (DSS) Induced Colitis

Gastroenterology (New York, N.Y. 1943), 2009, Vol.136 (5), p.A-151-A-151

2009

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W1661 Reduced Stimulation of NHE3 Activity and Reduced Exocytosis with Knockdown of Clc-5, An Endosomal Chloride Channel

Gastroenterology (New York, N.Y. 1943), 2009, Vol.136 (5), p.A-712-A-712

2009

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Amiloride-Sensitive Sodium Channels Contribute to the Woes of the Flu

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (18), p.9827-9829

2000

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High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease

Impaired acidification in early endosomes of ClC-5 deficient proximal tubule

Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion

Extracellular Acidification Alters Lysosomal Trafficking in Human Breast Cancer Cells

The Loss of the Chloride Channel, ClC-5, Delays Apical Iodide Efflux and Induces a Euthyroid Goiter in the Mouse Thyroid Gland

ClC-5: role in endocytosis in the proximal tubule

A New Insight into Pathophysiological Mechanisms of Zinc in Diarrhea

Mechanisms of Disease: what can mouse models tell us about the molecular processes underlying Dent disease?

NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity

The ClC‐5 Knockout Mouse Model of Dent's Disease Has Renal Hypercalciuria and Increased Bone Turnover

Chloride Channel (Clc)-5 Is Necessary for Exocytic Trafficking of Na+/H+ Exchanger 3 (NHE3)

Can we generate new hypotheses about Dent's disease from gene analysis of a mouse model?

Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins

Expression of a Truncated Cystic Fibrosis Transmembrane Conductance Regulator with an AAV5-pseudotyped Vector in Primates

L-type calcium channel activity in osteoblast cells is regulated by the actin cytoskeleton independent of protein trafficking

Clcn5 Knockout Mice Exhibit Novel Immunomodulatory Effects and Are More Susceptible to Dextran Sulfate Sodium-Induced Colitis

Transcriptional adaptation to Clcn5 knockout in proximal tubules of mouse kidney

Organic Solutes Rescue the Functional Defect in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator

Absence of ClC5 in Knockout Mice Leads to Glycosuria, Impaired Renal Glucose Handling and Low Proximal Tubule GLUT2 Protein Expression

The mRNA of L-Type Calcium Channel Elevated in Colon Cancer : Protein Distribution in Normal and Cancerous Colon

Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats

Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques

983 Clc-5 Knockout Mice Are More Susceptible to Dextran Sulphate Sodium (DSS) Induced Colitis

W1661 Reduced Stimulation of NHE3 Activity and Reduced Exocytosis with Knockdown of Clc-5, An Endosomal Chloride Channel

Amiloride-Sensitive Sodium Channels Contribute to the Woes of the Flu

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