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Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation

Drug metabolism and disposition, 2014-10, Vol.42 (10), p.1675-1683

2014

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Probenecid‐Boosted Tenofovir: A Physiologically‐Based Pharmacokinetic Model‐Informed Strategy for On‐Demand HIV Preexposure Prophylaxis

CPT: pharmacometrics and systems pharmacology, 2020-01, Vol.9 (1), p.40-47

2020

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Mass balance and pharmacokinetics of an oral dose of 14C‐napabucasin in healthy adult male subjects

Pharmacology research & perspectives, 2021-02, Vol.9 (1), p.n/a

2021

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Influence of CYP2B6 Pharmacogenetics on Stereoselective Inhibition and Induction of Bupropion Metabolism by Efavirenz in Healthy Volunteers

The Journal of pharmacology and experimental therapeutics, 2022-09, Vol.382 (3), p.313-326

2022

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A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies

Drug metabolism and disposition, 2020-10, Vol.48 (10), p.1104-1112

2020

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A phase 1 study of triple‐targeted therapy with BRAF, MEK, and AKT inhibitors for patients with BRAF‐mutated cancers

Cancer, 2024-05, Vol.130 (10), p.1784-1796

2024

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Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors

Drug metabolism and disposition, 2019-05, Vol.47 (5), p.535-544

2019

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Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo

Drug metabolism and disposition, 2016-04, Vol.44 (4), p.544-553

2016

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Circulating miRNAs as Biomarkers for CYP2B6 Enzyme Activity

Clinical pharmacology and therapeutics, 2021-02, Vol.109 (2), p.485-493

2021

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A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2R,6R)‐Hydroxynorketamine in Healthy Volunteers

Clinical pharmacology and therapeutics, 2024-11, Vol.116 (5), p.1314-1324

2024

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Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers

The Journal of pharmacology and experimental therapeutics, 2016-08, Vol.358 (2), p.230-238

2016

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Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product-Drug Interaction

Drug metabolism and disposition, 2015-09, Vol.43 (9), p.1353-1359

2015

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Variants in the CYP2B6 3′UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs

Clinical pharmacology and therapeutics, 2018-07, Vol.104 (1), p.130-138

2018

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The INGENIOUS trial: Impact of pharmacogenetic testing on adverse events in a pragmatic clinical trial

The pharmacogenomics journal, 2023-11, Vol.23 (6), p.169-177

2023

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Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs

Clinical pharmacology and therapeutics, 2018-07, Vol.104 (1), p.130

2018

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Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On‐Demand HIV Preexposure Prophylaxis

Clinical pharmacology and therapeutics, 2020-05, Vol.107 (5), p.1200-1208

2020

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Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers

Drug metabolism and disposition, 2020-03, Vol.48 (3), p.169-175

2020

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Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial

Pharmacogenomics, 2019-04, Vol.20 (6), p.397-408

2019

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Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial

Pharmacogenomics, 2017-06, Vol.18 (9), p.835-841

2017

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Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides

Drug metabolism and disposition, 2015-11, Vol.43 (11), p.1734-1743

2015

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Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (13), p.3919-3926

2013

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Rifampin modulation of xeno‐ and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes

Pharmacology research & perspectives, 2018-04, Vol.6 (2), p.e00386-n/a

2018

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Pharmacogenetics and Practice: Tailoring Prescribing for Safety and Effectiveness

Journal for nurse practitioners, 2018-11, Vol.14 (10), p.697-704.e1

2018

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Mass balance and pharmacokinetics of an oral dose of 14 C-napabucasin in healthy adult male subjects

Pharmacology research & perspectives, 2021-02, Vol.9 (1), p.e00722

2021

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Developing User Personas to Aid in the Design of a User-Centered Natural Product-Drug Interaction Information Resource for Researchers

AMIA ... Annual Symposium proceedings, 2018, Vol.2018, p.279-287

2018

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Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation

Probenecid‐Boosted Tenofovir: A Physiologically‐Based Pharmacokinetic Model‐Informed Strategy for On‐Demand HIV Preexposure Prophylaxis

Mass balance and pharmacokinetics of an oral dose of 14C‐napabucasin in healthy adult male subjects

Influence of CYP2B6 Pharmacogenetics on Stereoselective Inhibition and Induction of Bupropion Metabolism by Efavirenz in Healthy Volunteers

A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies

A phase 1 study of triple‐targeted therapy with BRAF, MEK, and AKT inhibitors for patients with BRAF‐mutated cancers

Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors

Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo

Circulating miRNAs as Biomarkers for CYP2B6 Enzyme Activity

A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2R,6R)‐Hydroxynorketamine in Healthy Volunteers

Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers

Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product-Drug Interaction

Variants in the CYP2B6 3′UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs

The INGENIOUS trial: Impact of pharmacogenetic testing on adverse events in a pragmatic clinical trial

Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs

Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On‐Demand HIV Preexposure Prophylaxis

Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers

Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial

Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial

Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides

Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle

Rifampin modulation of xeno‐ and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes

Pharmacogenetics and Practice: Tailoring Prescribing for Safety and Effectiveness

Mass balance and pharmacokinetics of an oral dose of 14 C-napabucasin in healthy adult male subjects

Developing User Personas to Aid in the Design of a User-Centered Natural Product-Drug Interaction Information Resource for Researchers

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