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Compartmentation of Glutathione: Implications for the Study of Toxicity and Disease

Toxicology and applied pharmacology, 1996-09, Vol.140 (1), p.1-12

1996

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Investigation of the role of the 2′,3′-epoxidation pathway in the bioactivation and genotoxicity of dietary allylbenzene analogs

Toxicology (Amsterdam), 2001-03, Vol.160 (1), p.47-58

2001

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Covalent binding to DNA in vitro of 2',3'-oxides derived from allylbenzene analogs

Drug metabolism and disposition, 1996-09, Vol.24 (9), p.1020

1996

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Detoxication of the 2',3'-epoxide metabolites of allylbenzene and estragole. Conjugation with glutathione

Drug metabolism and disposition, 1994-09, Vol.22 (5), p.731

1994

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Hydrolysis of the 2',3'-allylic epoxides of allylbenzene, estragole, eugenol, and safrole by both microsomal and cytosolic epoxide hydrolases

Drug metabolism and disposition, 1992-05, Vol.20 (3), p.440

1992

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Detection of human lung cytochromes P450 that are immunochemically related to cytochrome P450IIE1 and cytochrome P450IIIA

Biochemical pharmacology, 1992-07, Vol.44 (1), p.183-186

1992

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Direct measurement of melphalan conjugation with glutathione: studies with human melanoma cells and mammalian liver

The Journal of pharmacology and experimental therapeutics, 1992-03, Vol.260 (3), p.1331

1992

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Immunochemical analysis of a cytochrome P-450IA1 homologue in human lung microsomes

Molecular pharmacology, 1990-11, Vol.38 (5), p.634-643

1990

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Development of an in situ toxicity assay system using recombinant baculoviruses

Biochemical pharmacology, 1996-02, Vol.51 (4), p.503-515

1996

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Co-purification of microsomal epoxide hydrolase with the warfarin-sensitive vitamin K1 oxide reductase of the vitamin K cycle

Biochemical pharmacology, 1998-01, Vol.55 (2), p.169-175

1998

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Identification and characterization of a new epoxide hydrolase from mouse liver microsomes

The Journal of biological chemistry, 1983-12, Vol.258 (24), p.15054-15061

1983

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Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation

The Journal of biological chemistry, 1979-11, Vol.254 (22), p.11636-11648

1979

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Selective inhibition and selective induction of multiple microsomal epoxide hydrolases

Biochemical pharmacology, 1986-03, Vol.35 (5), p.839-845

Guenthner, Thomas M.

1986

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An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carbamazepine in vitro

Biochemical pharmacology, 1992-04, Vol.43 (8), p.1675-1682

1992

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Multiple epoxide hydrolases in human lung

Drug metabolism and disposition, 1986-03, Vol.14 (2), p.208

1986

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Cytosolic and microsomal epoxide hydrolases are immunologically distinguishable from each other in the rat and mouse

The Journal of biological chemistry, 1981-04, Vol.256 (7), p.3163-3166

1981

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Depletion of a discrete nuclear glutathione pool by oxidative stress, but not by buthionine sulfoximine: Correlation with enhanced alkylating agent cytotoxicity to human melanoma cells in vitro

Biochemical pharmacology, 1992-10, Vol.44 (7), p.1383-1393

1992

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32P-postlabeling analysis of adducts formed between DNA and safrole 2′,3′-epoxide: absence of adduct formation in vivo

Toxicology letters, 1995, Vol.75 (1), p.201-207

1995

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Characterization of multiple epoxide hydrolase activities in mouse liver nuclear envelope

Biochemical pharmacology, 1986-10, Vol.35 (19), p.3261-3266

Guenthner, Thomas M.

1986

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Inhibition of catalase and epoxide hydrolase by the renal cystogen 2-amino-4,5-diphenylthiazole and its metabolites

Toxicology (Amsterdam), 1990-03, Vol.60 (3), p.211-222

1990

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[33] Purification of warfarin-sensitive vitamin K epoxide reductase

Methods in Enzymology, 1997, Vol.282, p.395-408

1997

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Production of monospecific antiserum to a cytosolic epoxide hydrolase from human liver

Biochemical pharmacology, 1990-01, Vol.39 (2), p.293-300

1990

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Existence of multiple forms of microsomal epoxide hydrolases with radically different substrate specificities

Carcinogenesis (New York), 1984-01, Vol.5 (1), p.7-9

1984

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Focal elevation of liver microsomal epoxide hydrolase in early preneoplastic stages and its behaviour in the further course of hepatocarcinogenesis

Biochemical and biophysical research communications, 1981-01, Vol.98 (2), p.417-423

1981

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Metabolism of allylbenzene 2',3'-oxide and estragole 2',3'-oxide in the isolated perfused rat liver

The Journal of pharmacology and experimental therapeutics, 1995-02, Vol.272 (2), p.588

1995

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Compartmentation of Glutathione: Implications for the Study of Toxicity and Disease

Investigation of the role of the 2′,3′-epoxidation pathway in the bioactivation and genotoxicity of dietary allylbenzene analogs

Covalent binding to DNA in vitro of 2',3'-oxides derived from allylbenzene analogs

Detoxication of the 2',3'-epoxide metabolites of allylbenzene and estragole. Conjugation with glutathione

Hydrolysis of the 2',3'-allylic epoxides of allylbenzene, estragole, eugenol, and safrole by both microsomal and cytosolic epoxide hydrolases

Detection of human lung cytochromes P450 that are immunochemically related to cytochrome P450IIE1 and cytochrome P450IIIA

Direct measurement of melphalan conjugation with glutathione: studies with human melanoma cells and mammalian liver

Immunochemical analysis of a cytochrome P-450IA1 homologue in human lung microsomes

Development of an in situ toxicity assay system using recombinant baculoviruses

Co-purification of microsomal epoxide hydrolase with the warfarin-sensitive vitamin K1 oxide reductase of the vitamin K cycle

Identification and characterization of a new epoxide hydrolase from mouse liver microsomes

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation

Selective inhibition and selective induction of multiple microsomal epoxide hydrolases

An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carbamazepine in vitro

Multiple epoxide hydrolases in human lung

Cytosolic and microsomal epoxide hydrolases are immunologically distinguishable from each other in the rat and mouse

Depletion of a discrete nuclear glutathione pool by oxidative stress, but not by buthionine sulfoximine: Correlation with enhanced alkylating agent cytotoxicity to human melanoma cells in vitro

32P-postlabeling analysis of adducts formed between DNA and safrole 2′,3′-epoxide: absence of adduct formation in vivo

Characterization of multiple epoxide hydrolase activities in mouse liver nuclear envelope

Inhibition of catalase and epoxide hydrolase by the renal cystogen 2-amino-4,5-diphenylthiazole and its metabolites

[33] Purification of warfarin-sensitive vitamin K epoxide reductase

Production of monospecific antiserum to a cytosolic epoxide hydrolase from human liver

Existence of multiple forms of microsomal epoxide hydrolases with radically different substrate specificities

Focal elevation of liver microsomal epoxide hydrolase in early preneoplastic stages and its behaviour in the further course of hepatocarcinogenesis

Metabolism of allylbenzene 2',3'-oxide and estragole 2',3'-oxide in the isolated perfused rat liver

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