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Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

Nature communications, 2020-12, Vol.11 (1), p.6363-15, Article 6363

2020

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Mycolactone subverts immunity by selectively blocking the Sec61 translocon

The Journal of experimental medicine, 2016-12, Vol.213 (13), p.2885-2896

2016

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Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature

Molecular & cellular proteomics, 2018-09, Vol.17 (9), p.1750-1765

2018

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Preclinical proof of principle for orally delivered Th17 antagonist miniproteins

Cell, 2024-08, Vol.187 (16), p.4305-4317.e18

2024

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Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone

Frontiers in pharmacology, 2021-09, Vol.12, p.733496-733496

2021

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De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

eLife, 2021-12, Vol.10

2021

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Synthetic Variants of Mycolactone Bind and Activate Wiskott–Aldrich Syndrome Proteins

Journal of medicinal chemistry, 2014-09, Vol.57 (17), p.7382-7395

2014

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Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation

The Journal of clinical investigation, 2013-04, Vol.123 (4), p.1501-1512

2013

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A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

Chemistry : a European journal, 2011-12, Vol.17 (51), p.14413-14419

2011

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Mycolactone displays anti-inflammatory effects on the nervous system

PLoS neglected tropical diseases, 2017-11, Vol.11 (11), p.e0006058-e0006058

2017

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Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

PLoS neglected tropical diseases, 2020-12, Vol.14 (12), p.e0008878

2020

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Shaping mycolactone for therapeutic use against inflammatory disorders

Science translational medicine, 2015-05, Vol.7 (289), p.289ra85

2015

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Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (31), p.12833-12838

2011

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Immunosuppressive Signature of Cutaneous Mycobacterium ulcerans Infection in the Peripheral Blood of Patients with Buruli Ulcer Disease

The Journal of infectious diseases, 2009-12, Vol.200 (11), p.1675-1684

2009

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Dysregulation of tryptophan catabolism at the host-skin microbiota interface in hidradenitis suppurativa

JCI insight, 2020-10, Vol.5 (20)

2020

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Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring

PLoS neglected tropical diseases, 2011-07, Vol.5 (7), p.e1237-e1237

2011

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Cover Picture: A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins (Chem. Eur. J. 51/2011)

Chemistry : a European journal, 2011-12, Vol.17 (51), p.14305-14305

2011

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Mycolactone Suppresses T Cell Responsiveness by Altering Both Early Signaling and Posttranslational Events

The Journal of immunology (1950), 2010-02, Vol.184 (3), p.1436-1444

2010

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Modular total syntheses of mycolactone A/B and its [ 2 H]-isotopologue

Organic & biomolecular chemistry, 2017-09, Vol.15 (36), p.7518-7522

2017

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Pathogenesis of skin ulcers: lessons from the Mycobacterium ulcerans and Leishmania spp. pathogens

Cellular and molecular life sciences : CMLS, 2014-07, Vol.71 (13), p.2443-2450

2014

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Lipids of Pathogenic Mycobacteria: Contributions to Virulence and Host Immune Suppression

Transboundary and emerging diseases, 2009-08, Vol.56 (6-7), p.255-268

2009

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Mycolactone Purification from M. ulcerans Cultures and HPLC-Based Approaches for Mycolactone Quantification in Biological Samples

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2387, p.117

2022

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Mycolactone: More than Just a Cytotoxin

Buruli Ulcer, 2019, p.117-134

2019

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Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease

Scientific reports, 2015-12, Vol.5 (1), p.17693-17693, Article 17693

2015

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Host immunomodulation by mycolactone, the Mycobacterium ulcerans toxin

Toxicon (Oxford), 2018-07, Vol.149, p.91-91

2018

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Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

Mycolactone subverts immunity by selectively blocking the Sec61 translocon

Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature

Preclinical proof of principle for orally delivered Th17 antagonist miniproteins

Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone

De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

Synthetic Variants of Mycolactone Bind and Activate Wiskott–Aldrich Syndrome Proteins

Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation

A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

Mycolactone displays anti-inflammatory effects on the nervous system

Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

Shaping mycolactone for therapeutic use against inflammatory disorders

Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression

Immunosuppressive Signature of Cutaneous Mycobacterium ulcerans Infection in the Peripheral Blood of Patients with Buruli Ulcer Disease

Dysregulation of tryptophan catabolism at the host-skin microbiota interface in hidradenitis suppurativa

Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring

Cover Picture: A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins (Chem. Eur. J. 51/2011)

Mycolactone Suppresses T Cell Responsiveness by Altering Both Early Signaling and Posttranslational Events

Modular total syntheses of mycolactone A/B and its [ 2 H]-isotopologue

Pathogenesis of skin ulcers: lessons from the Mycobacterium ulcerans and Leishmania spp. pathogens

Lipids of Pathogenic Mycobacteria: Contributions to Virulence and Host Immune Suppression

Mycolactone Purification from M. ulcerans Cultures and HPLC-Based Approaches for Mycolactone Quantification in Biological Samples

Mycolactone: More than Just a Cytotoxin

Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease

Host immunomodulation by mycolactone, the Mycobacterium ulcerans toxin

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