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Oxidation of Endogenous N-Arachidonoylserotonin by Human Cytochrome P450 2U1

The Journal of biological chemistry, 2014-04, Vol.289 (15), p.10476-10487

2014

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Oxidation of Dihydrotestosterone by Human Cytochromes P450 19A1 and 3A4

The Journal of biological chemistry, 2012-08, Vol.287 (35), p.29554-29567

2012

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Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

Chemico-Biological Interactions, 1997-10, Vol.106 (3), p.161-182

Guengerich, F.Peter

1997

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Roles of NADPH-P450 Reductase and Apo- and Holo-Cytochrome b5 on Xenobiotic Oxidations Catalyzed by 12 Recombinant Human Cytochrome P450s Expressed in Membranes of Escherichia coli

Protein expression and purification, 2002-04, Vol.24 (3), p.329-337

2002

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Translesion Synthesis across 1,N6-(2-Hydroxy-3-hydroxymethylpropan-1,3-diyl)-2′-deoxyadenosine (1,N6-γ-HMHP-dA) Adducts by Human and Archebacterial DNA Polymerases

The Journal of biological chemistry, 2012-11, Vol.287 (46), p.38800-38811

2012

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Etheno adducts : from tRNA modifications to DNA adducts and back to miscoding ribonucleotides

Genes and Environment, 2021, Vol.43 (24), p.1-23

2021

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Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development

DRUG METABOLISM AND PHARMACOKINETICS, 2011-01, Vol.26 (1), p.3-14

Guengerich, F. Peter

2011

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Expression of Human Cytochrome P450 2B6 in Escherichia coli: Characterization of Catalytic Activity and Expression Levels in Human Liver

Archives of biochemistry and biophysics, 2000-04, Vol.376 (1), p.206-216

2000

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Functional characterization of four allelic variants of human cytochrome P450 1A2

Archives of biochemistry and biophysics, 2004-02, Vol.422 (1), p.23-30

2004

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Comparative Studies on the Catalytic Roles of Cytochrome P450 2C9 and Its Cys- and Leu-Variants in the Oxidation of Warfarin, Flurbiprofen, and Diclofenac by Human Liver Microsomes

Biochemical pharmacology, 1998-07, Vol.56 (2), p.243-251

1998

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Formation of Indigo by Recombinant Mammalian Cytochrome P450

Biochemical and biophysical research communications, 1999-11, Vol.265 (2), p.469-472

1999

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Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications

The Journal of biological chemistry, 2020-01, Vol.295 (3), p.833-849

2020

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Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

Carcinogenesis (New York), 1992-10, Vol.13 (10), p.1789-1794

1992

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Xenobiotic-metabolizing Cytochromes P450 Convert Prostaglandin Endoperoxide to Hydroxyheptadecatrienoic Acid and the Mutagen, Malondialdehyde

The Journal of biological chemistry, 2000-04, Vol.275 (16), p.11784-11790

2000

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Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase

Mutation research, 2001-05, Vol.492 (1), p.81-90

2001

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Colchicine biotransformation by human liver microsomes

Biochemical pharmacology, 1997-01, Vol.53 (1), p.111-116

1997

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Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains

Mutagenesis, 2006-11, Vol.21 (6), p.411-416

2006

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The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines

Carcinogenesis (New York), 2001-06, Vol.22 (6), p.943-950

2001

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7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes

Biochemical pharmacology, 1996-02, Vol.51 (3), p.313-319

1996

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Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate

Carcinogenesis (New York), 1996-04, Vol.17 (4), p.809-813

1996

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Human Cytochrome P450 2E1 Mutations That Alter Mitochondrial Targeting Efficiency and Susceptibility to Ethanol-induced Toxicity in Cellular Models

The Journal of biological chemistry, 2013-05, Vol.288 (18), p.12627-12644

2013

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Translesion Synthesis across O6-Alkylguanine DNA Adducts by Recombinant Human DNA Polymerases

The Journal of biological chemistry, 2006-12, Vol.281 (50), p.38244-38256

2006

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On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO

Journal of lipid research, 2014-06, Vol.55 (6), p.1165-1172

2014

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Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η

The Journal of biological chemistry, 2016-07, Vol.291 (27), p.14134-14145

2016

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Adduct Size Limits Efficient and Error-free Bypass Across Bulky N 2-Guanine DNA Lesions by Human DNA Polymerase η

Journal of molecular biology, 2005-09, Vol.352 (1), p.72-90

2005

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Oxidation of Endogenous N-Arachidonoylserotonin by Human Cytochrome P450 2U1

Oxidation of Dihydrotestosterone by Human Cytochromes P450 19A1 and 3A4

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

Roles of NADPH-P450 Reductase and Apo- and Holo-Cytochrome b5 on Xenobiotic Oxidations Catalyzed by 12 Recombinant Human Cytochrome P450s Expressed in Membranes of Escherichia coli

Translesion Synthesis across 1,N6-(2-Hydroxy-3-hydroxymethylpropan-1,3-diyl)-2′-deoxyadenosine (1,N6-γ-HMHP-dA) Adducts by Human and Archebacterial DNA Polymerases

Etheno adducts : from tRNA modifications to DNA adducts and back to miscoding ribonucleotides

Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development

Expression of Human Cytochrome P450 2B6 in Escherichia coli: Characterization of Catalytic Activity and Expression Levels in Human Liver

Functional characterization of four allelic variants of human cytochrome P450 1A2

Comparative Studies on the Catalytic Roles of Cytochrome P450 2C9 and Its Cys- and Leu-Variants in the Oxidation of Warfarin, Flurbiprofen, and Diclofenac by Human Liver Microsomes

Formation of Indigo by Recombinant Mammalian Cytochrome P450

Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

Xenobiotic-metabolizing Cytochromes P450 Convert Prostaglandin Endoperoxide to Hydroxyheptadecatrienoic Acid and the Mutagen, Malondialdehyde

Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase

Colchicine biotransformation by human liver microsomes

Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains

The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines

7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate

Human Cytochrome P450 2E1 Mutations That Alter Mitochondrial Targeting Efficiency and Susceptibility to Ethanol-induced Toxicity in Cellular Models

Translesion Synthesis across O6-Alkylguanine DNA Adducts by Recombinant Human DNA Polymerases

On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO

Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η

Adduct Size Limits Efficient and Error-free Bypass Across Bulky N 2-Guanine DNA Lesions by Human DNA Polymerase η

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