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The small compound Icerguastat reduces muscle defects in oculopharyngeal muscular dystrophy through the PERK pathway of the unfolded protein response

Open biology, 2023-04, Vol.13 (4), p.230008-230008

2023

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Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells

Molecular cancer therapeutics, 2009-08, Vol.8 (8), p.2286-2295

2009

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Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy

Human molecular genetics, 2019-05, Vol.28 (10), p.1694-1708

2019

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A Rat Model of Clinically Relevant Extracorporeal Circulation Develops Early Organ Dysfunctions

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7338

2023

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Control of the Unfolded Protein Response in Health and Disease

SLAS Discovery, 2017-08, Vol.22 (7), p.787-800

2017

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Patented small molecule inhibitors in the ubiquitin proteasome system

BMC biochemistry, 2007-11, Vol.8 Suppl 1 (Suppl 1), p.S14-S14

2007

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Treatment with IFB-088 Improves Neuropathy in CMT1A and CMT1B Mice

Molecular neurobiology, 2022-07, Vol.59 (7), p.4159-4178

2022

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Gemini Surfactants: New Synthetic Vectors for Gene Transfection

Angewandte Chemie International Edition, 2003-04, Vol.42 (13), p.1448-1457

2003

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Synthesis and Biological Evaluation of 9-Oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile Analogues as Potential Inhibitors of Deubiquitinating Enzymes

ChemMedChem, 2010-04, Vol.5 (4), p.552-558

2010

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Sa1079 CVVS-732: A Conformational Modulator of NS5B Polymerase Acting a Potent HCV Inhibitor

Gastroenterology (New York, N.Y. 1943), 2012-05, Vol.142 (5), p.S-963-S-963

2012

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Abstract 2642: Identification and characterization of selective inhibitors of ubiquitin specific protease 7

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2642-2642

2010

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Abstract B193: Identification of selective inhibitors of ubiquitin specific proteases

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.B193-B193

2009

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The 3D-Screen Technology, an Innovative Cell-based Assay to Identify Modulators that Alter Target Protein Conformation: Example with HCV

Antiviral research, 2011-05, Vol.90 (2), p.A77-A77

2011

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Synthesis and Biological Evaluation of 9‐Oxo‐9 H ‐indeno[1,2‐ b ]pyrazine‐2,3‐dicarbonitrile Analogues as Potential Inhibitors of Deubiquitinating Enzymes

ChemMedChem, 2010-04, Vol.5 (4), p.552-558

2010

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Novel spermine-based cationic gemini surfactants for gene delivery

Chemical communications (Cambridge, England), 2001-11 (21), p.2234-2235

2001

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Inframolecular acid–base studies of the tris and tetrakis myo-inositol phosphates including the 1,2,3-trisphosphate motif

Journal of molecular structure, 2002-12, Vol.643 (1), p.171-181

2002

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A Conformationally Restricted Cyclic Phosphate Analogue of Inositol Trisphosphate: Synthesis and Physicochemical Properties

Journal of organic chemistry, 1998-01, Vol.63 (2), p.295-305

1998

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Synthesis, Acid−Base Behavior, and Binding Properties of 6-Modified myo-Inositol 1,4,5-Tris(phosphate)s

Journal of medicinal chemistry, 1999-11, Vol.42 (23), p.4824-4835

1999

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Patented Molecule Inhibitors in the UPS

Targeted Protein Database, 2007-08

Guédat, Philippe

2007

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Synthesis of (±)-4-deoxy-4-fluoro- myo-inositol

Tetrahedron letters, 1995-10, Vol.36 (41), p.7449-7450

1995

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Synthesis of (±) 1,2-dideoxy-1,2-diamino- myo-inositol

Tetrahedron letters, 1994-10, Vol.35 (40), p.7375-7378

1994

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Rapid synthesis and properties of (±)-6-Deoxy-6-fluoro- myo-inositol-1,4,5-tris(phosphate) an analogue of myo-inositol-1,4,5-tris(phosphate)

Bioorganic & medicinal chemistry letters, 1996-05, Vol.6 (10), p.1175-1178

1996

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ChemInform Abstract: Novel Spermine-Based Cationic Gemini Surfactants for Gene Delivery

ChemInform, 2002-03, Vol.33 (10), p.no-no

2002

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Investigation of the inframolecular acid–base properties of d-myo-inositol 1,3,4,5-tetrakisphosphate and dl-myo-inositol 1,2,4,5-tetrakisphosphate

Chemical communications (Cambridge, England), 1997 (6), p.625-626

1997

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Gemini-Tenside: neue synthetische Vektoren zur Gentransfektion

Angewandte Chemie, 2003-04, Vol.115 (13), p.1486-1496

2003

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The small compound Icerguastat reduces muscle defects in oculopharyngeal muscular dystrophy through the PERK pathway of the unfolded protein response

Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells

Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy

A Rat Model of Clinically Relevant Extracorporeal Circulation Develops Early Organ Dysfunctions

Control of the Unfolded Protein Response in Health and Disease

Patented small molecule inhibitors in the ubiquitin proteasome system

Treatment with IFB-088 Improves Neuropathy in CMT1A and CMT1B Mice

Gemini Surfactants: New Synthetic Vectors for Gene Transfection

Synthesis and Biological Evaluation of 9-Oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile Analogues as Potential Inhibitors of Deubiquitinating Enzymes

Sa1079 CVVS-732: A Conformational Modulator of NS5B Polymerase Acting a Potent HCV Inhibitor

Abstract 2642: Identification and characterization of selective inhibitors of ubiquitin specific protease 7

Abstract B193: Identification of selective inhibitors of ubiquitin specific proteases

The 3D-Screen Technology, an Innovative Cell-based Assay to Identify Modulators that Alter Target Protein Conformation: Example with HCV

Synthesis and Biological Evaluation of 9‐Oxo‐9 H ‐indeno[1,2‐ b ]pyrazine‐2,3‐dicarbonitrile Analogues as Potential Inhibitors of Deubiquitinating Enzymes

Novel spermine-based cationic gemini surfactants for gene delivery

Inframolecular acid–base studies of the tris and tetrakis myo-inositol phosphates including the 1,2,3-trisphosphate motif

A Conformationally Restricted Cyclic Phosphate Analogue of Inositol Trisphosphate: Synthesis and Physicochemical Properties

Synthesis, Acid−Base Behavior, and Binding Properties of 6-Modified myo-Inositol 1,4,5-Tris(phosphate)s

Patented Molecule Inhibitors in the UPS

Synthesis of (±)-4-deoxy-4-fluoro- myo-inositol

Synthesis of (±) 1,2-dideoxy-1,2-diamino- myo-inositol

Rapid synthesis and properties of (±)-6-Deoxy-6-fluoro- myo-inositol-1,4,5-tris(phosphate) an analogue of myo-inositol-1,4,5-tris(phosphate)

ChemInform Abstract: Novel Spermine-Based Cationic Gemini Surfactants for Gene Delivery

Investigation of the inframolecular acid–base properties of d-myo-inositol 1,3,4,5-tetrakisphosphate and dl-myo-inositol 1,2,4,5-tetrakisphosphate

Gemini-Tenside: neue synthetische Vektoren zur Gentransfektion

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